scholarly journals Spectroscopic photoacoustic imaging of radiofrequency ablation in the left atrium

2018 ◽  
Vol 9 (3) ◽  
pp. 1309 ◽  
Author(s):  
Sophinese Iskander-Rizk ◽  
Pieter Kruizinga ◽  
Antonius F. W. van der Steen ◽  
Gijs van Soest
Author(s):  
Carolyn G. Norwood ◽  
W. David Merryman

The mitral valve (MV), located between the left atrium and left ventricle of the heart, is responsible for preventing retrograde blood flow by closing during systole. There are two MV leaflets, anterior and posterior. The anterior is the larger of the two and semicircular; the posterior leaflet is more rectangular and can be subdivided into three scallops, the middle scallop being the largest in most human hearts. The two leaflets are anchored to the wall of the left ventricle by the chordae tendinae. The MV annulus forms a complete fibrous ring anchored along the anterior leaflet (1).


Circulation ◽  
2005 ◽  
Vol 112 (4) ◽  
pp. 459-464 ◽  
Author(s):  
Jennifer E. Cummings ◽  
Robert A. Schweikert ◽  
Walid I. Saliba ◽  
J. David Burkhardt ◽  
Johannes Brachmann ◽  
...  

2017 ◽  
Vol 17 (1) ◽  
Author(s):  
Vilius Kviesulaitis ◽  
Aras Puodziukynas ◽  
Dainius Haroldas Pauza ◽  
Vytautas Zabiela ◽  
Tomas Kazakevicius ◽  
...  

2001 ◽  
Vol 22 (3) ◽  
pp. 204-209 ◽  
Author(s):  
I.H. Law ◽  
P.S. Fischbach ◽  
S. LeRoy ◽  
T.R. Lloyd ◽  
A.P. Rocchini ◽  
...  

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Xiaowei Zhao ◽  
Ohad Ziv ◽  
Reza Mohammadpour ◽  
Benjamin Crosby ◽  
Walter J. Hoyt ◽  
...  

AbstractRadiofrequency ablation (RFA) is commonly used to treat atrial fibrillation (AF). However, the outcome is often compromised due to the lack of direct real-time feedback to assess lesion transmurality. In this work, we evaluated the ability of polarization-sensitive optical coherence tomography (PSOCT) to measure cardiac wall thickness and assess RF lesion transmurality during left atrium (LA) RFA procedures. Quantitative transmural lesion criteria using PSOCT images were determined ex vivo using an integrated PSOCT-RFA catheter and fresh swine hearts. LA wall thickness of living swine was measured with PSOCT and validated with a micrometer after harvesting the heart. A total of 38 point lesions were created in the LA of 5 living swine with the integrated PSOCT-RFA catheter using standard clinical RFA procedures. For all lesions with analyzable PSOCT images, lesion transmurality was assessed with a sensitivity of 89% (17 of 19 tested positive) and a specificity of 100% (5 of 5 tested negative) using the quantitative transmural criteria. This is the first report of using PSOCT to assess LA RFA lesion transmurality in vivo. The results indicate that PSOCT may potentially provide direct real-time feedback for LA wall thickness and lesion transmurality.


EP Europace ◽  
2020 ◽  
Vol 22 (Supplement_1) ◽  
Author(s):  
T Zolotarova

Abstract Introduction. Randomized controlled trials and meta-analyzes have shown high efficacy of the radiofrequency ablation (RFA) for both initial and secondary strategies after unsuccessful drug therapy (DT) to maintain sinus rhythm (SR) and improve functional and morphological quality of life; in patients with chronic heart failure (CHF), RFA were associated with a significant relative reduction in the risk of overall mortality, atrial fibrillation (AF) recurrence, and hospitalization for cardiac pathology (compared with DT). High risk of arrhythmia recurrence (up to 45% within 6 - 12 months after intervention) remains a major RFA problem. Purpose. to evaluate predictive properties of demographic, hemodynamic and electrocardiographic parameters for recurrence after atrial fibrillation ablation in patients with chronic heart failure with preserved ejection fraction. Methods. We included 120 patients, aged 59.80 ± 10.08 years with CHF with preserved ejection fraction (EF) of left ventricle (LV) who underwent first time RFA for AF with LV EF(> 40%) I-III FC NYHA. Baseline clinical data, ECG before and after the procedure, ECHO parameters were collected Results Thirty-two patients had AF recurrence after a mean follow-up of twelve months. Those experiencing recurrence were more female (50% vs.39%, p <0,01), had a longer QTc interval before ablation than those without recurrence (387,23 ± 2,31 vs. 341,22 ± 8,91 ms, p < 0,01) and after ablation (439,01 ± 4,73 vs. 373,21 ± 7,92 ms, p < 0,001), lower LV EF (59% vs. 63%, p < 0,05), higher left atrium diameter (4,59 ± 0,45 vs. 4,08 ± 0,61 cm, p < 0,001) and higher mean pulmonary artery gradient (32,86 ± 9,67 vs. 25,15 ± 9,73, p < 0,01). Conclusions. QTc duration to radiofrequency ablation and its prolongation after intervention are independent predictors of arrhythmia recurrence in patients with chronic heart failure with a preserved left ventricular ejection fraction. The size of the left atrium before ablation is a highly sensitive predictor of recurrence of arrhythmia


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