scholarly journals Development of a multi-wavelength diffuse optical tomography system for early diagnosis of rheumatoid arthritis: simulation, phantoms and healthy human studies

2016 ◽  
Vol 7 (11) ◽  
pp. 4769 ◽  
Author(s):  
Hao Yang Wu ◽  
Andrew Filer ◽  
Iain Styles ◽  
Hamid Dehghani
Keyword(s):  
Rheumatoid Arthritis ◽  
Early Diagnosis ◽  
Optical Tomography ◽  
Diffuse Optical Tomography ◽  
Human Studies ◽  
Healthy Human ◽  
Tomography System ◽  
Multi Wavelength

scholarly journals Design and implementation of a multifrequency near-infrared diffuse optical tomography system

2006 ◽  
Vol 11 (1) ◽  
pp. 014020 ◽  
Author(s):  
Gultekin Gulsen ◽  
Bin Xiong ◽  
Ozlem Birgul ◽  
Orhan Nalcioglu
Keyword(s):  
Near Infrared ◽  
Optical Tomography ◽  
Diffuse Optical Tomography ◽  
Design And Implementation ◽  
Tomography System

scholarly journals Functional imaging of the human brain using a modular, fibre-less, high-density diffuse optical tomography system

2016 ◽  
Vol 7 (10) ◽  
pp. 4275 ◽  
Author(s):  
Danial Chitnis ◽  
Robert J. Cooper ◽  
Laura Dempsey ◽  
Samuel Powell ◽  
Simone Quaggia ◽  
...  
Keyword(s):  
Human Brain ◽  
Functional Imaging ◽  
Optical Tomography ◽  
Diffuse Optical Tomography ◽  
High Density ◽  
Tomography System

scholarly journals Real-Time Dual-Wavelength Time-Resolved Diffuse Optical Tomography System for Functional Brain Imaging Based on Probe-Hosted Silicon Photomultipliers

Sensors ◽  
2020 ◽  
Vol 20 (10) ◽  
pp. 2815
Author(s):  
David Orive-Miguel ◽  
Laura Di Sieno ◽  
Anurag Behera ◽  
Edoardo Ferocino ◽  
Davide Contini ◽  
...  
Keyword(s):  
Brain Imaging ◽  
Near Infrared ◽  
Optical Tomography ◽  
Diffuse Optical Tomography ◽  
Brain Activation ◽  
Functional Brain Imaging ◽  
Dual Wavelength ◽  
Silicon Photomultipliers ◽  
Functional Brain ◽  
Tomography System

Near-infrared diffuse optical tomography is a non-invasive photonics-based imaging technology suited to functional brain imaging applications. Recent developments have proved that it is possible to build a compact time-domain diffuse optical tomography system based on silicon photomultipliers (SiPM) detectors. The system presented in this paper was equipped with the same eight SiPM probe-hosted detectors, but was upgraded with six injection fibers to shine the sample at several points. Moreover, an automatic switch was included enabling a complete measurement to be performed in less than one second. Further, the system was provided with a dual-wavelength (670 n m and 820 n m ) light source to quantify the oxy- and deoxy-hemoglobin concentration evolution in the tissue. This novel system was challenged against a solid phantom experiment, and two in-vivo tests, namely arm occlusion and motor cortex brain activation. The results show that the tomographic system makes it possible to follow the evolution of brain activation over time with a 1 s -resolution.

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