scholarly journals Towards next-generation time-domain diffuse optics for extreme depth penetration and sensitivity

2015 ◽  
Vol 6 (5) ◽  
pp. 1749 ◽  
Author(s):  
Alberto Dalla Mora ◽  
Davide Contini ◽  
Simon Arridge ◽  
Fabrizio Martelli ◽  
Alberto Tosi ◽  
...  
Keyword(s):  
Time Domain ◽  
Generation Time ◽  
Next Generation ◽  
Diffuse Optics

scholarly journals Towards next generation time-domain diffuse optics devices

2015 ◽  
Author(s):  
Alberto Dalla Mora ◽  
Davide Contini ◽  
Simon R. Arridge ◽  
Fabrizio Martelli ◽  
Alberto Tosi ◽  
...  
Keyword(s):  
Time Domain ◽  
Generation Time ◽  
Next Generation ◽  
Diffuse Optics

Time-domain diffuse optics: towards next generation devices

2015 ◽  
Author(s):  
Davide Contini ◽  
Alberto Dalla Mora ◽  
Simon Arridge ◽  
Fabrizio Martelli ◽  
Alberto Tosi ◽  
...  
Keyword(s):  
Time Domain ◽  
Next Generation ◽  
Diffuse Optics

Time-domain diffuse optics: towards next generation devices

2015 ◽  
Author(s):  
Davide Contini ◽  
Alberto Dalla Mora ◽  
Simon Arridge ◽  
Fabrizio Martelli ◽  
Alberto Tosi ◽  
...  
Keyword(s):  
Time Domain ◽  
Next Generation ◽  
Diffuse Optics

scholarly journals Single-Photon Detection Module Based on Large-Area Silicon Photomultipliers for Time-Domain Diffuse Optics

Instruments ◽  
2021 ◽  
Vol 5 (2) ◽  
pp. 18
Author(s):  
Fabio Acerbi ◽  
Anurag Behera ◽  
Alberto Dalla Mora ◽  
Laura Di Sieno ◽  
Alberto Gola
Keyword(s):  
Time Resolution ◽  
Time Domain ◽  
Single Photon ◽  
Building Blocks ◽  
The Body ◽  
Single Photon Detection ◽  
Silicon Photomultipliers ◽  
Photon Detection ◽  
Instrument Response Function ◽  
Diffuse Optics

Silicon photomultipliers (SiPM) are pixelated single-photon detectors combining high sensitivity, good time resolution and high dynamic range. They are emerging in many fields, such as time-domain diffuse optics (TD-DO). This is a promising technique in neurology, oncology, and quality assessment of food, wood, and pharmaceuticals. SiPMs can have very large areas and can significantly increase the sensitivity of TD-DO in tissue investigation. However, such improvement is currently limited by the high detector noise and the worsening of SiPM single-photon time resolution due to the large parasitic capacitances. To overcome such limitation, in this paper, we present two single-photon detection modules, based on 6 × 6 mm2 and 10 × 10 mm2 SiPMs, housed in vacuum-sealed TO packages, cooled to −15 °C and −36 °C, respectively. They integrate front-end amplifiers and temperature controllers, being very useful instruments for TD-DO and other biological and physical applications. The signal extraction from the SiPM was improved. The noise is reduced by more than two orders of magnitude compared to the room temperature level. The full suitability of the proposed detectors for TD-DO measurements is outside the scope of this work, but preliminary tests were performed analyzing the shape and the stability of the Instrument Response Function. The proposed modules are thus fundamental building blocks to push the TD-DO towards deeper investigations inside the body.

scholarly journals LSST and the Epoch of Reionization Experiments

2017 ◽  
Vol 12 (S333) ◽  
pp. 222-227
Author(s):  
Željko Ivezić
Keyword(s):  
Dark Matter ◽  
Dark Energy ◽  
Time Domain ◽  
Point Sources ◽  
Field Of View ◽  
Next Generation ◽  
Imaging Data ◽  
Primary Mirror ◽  
Scientific Investigations ◽  
Near Earth Asteroids

AbstractThe Large Synoptic Survey Telescope (LSST), a next generation astronomical survey, sited on Cerro Pachon in Chile, will provide an unprecedented amount of imaging data for studies of the faint optical sky. The LSST system includes an 8.4m (6.7m effective) primary mirror and a 3.2 Gigapixel camera with a 9.6 sq. deg. field of view. This system will enable about 10,000 sq. deg. of sky to be covered twice per night, every three to four nights on average, with typical 5-sigma depth for point sources ofr= 24.5 (AB). With over 800 observations in theugrizybands over a 10-year period, these data will enable coadded images reachingr= 27.5 (about 5 magnitudes deeper than SDSS) as well as studies of faint time-domain astronomy. The measured properties of newly discovered and known astrometric and photometric transients will be publicly reported within 60 sec after closing the shutter. The resulting hundreds of petabytes of imaging data for about 40 billion objects will be used for scientific investigations ranging from the properties of near-Earth asteroids to characterizations of dark matter and dark energy. For example, simulations estimate that LSST will discover about 1,000 quasars at redshifts exceeding 7; this sample will place tight constraints on the cosmic environment at the end of the reionization epoch. In addition to a brief introduction to LSST, I review the value of LSST data in support of epoch of reionization experiments and discuss how international participants can join LSST.

Next Generation of Soil-Structure Interaction Models for Design of Nuclear Power Plants

2014 ◽  
Vol 9 (1) ◽  
pp. 3-16 ◽  
Author(s):  
Alexander G. Tyapin ◽  
Keyword(s):  
Time Domain ◽  
Soil Structure ◽  
Power Plants ◽  
Near Field ◽  
Soil Structure Interaction ◽  
Current Status ◽  
Computational Techniques ◽  
Next Generation ◽  
Structure Interaction ◽  
Wave Effects

The author here shares his vision of next-generation models for seismic soil-structure interaction (SSI) analysis. These models should combine reasonable considerations of wave effects in half-infinite soil with a correct representation of nonlinearity in the structure, and in both the so-called near field, i.e., in that part of soil near a base mat, and in the soil-structure contact surface. The far field, i.e., all of the soil except for the near field, is treated as a linear horizontally layered medium, as is currently done in the well-known program SASSI. The importance of considering nonlinear effects even in very stiff structures like NPPs was shown by the March 2011 Great East Japan Earthquake that hit northeastern Japan’s Pacific coast. Although the idea of calculating SSI wave effects in the time domain has been around for several decades ago, current NPP design practices are linear. Next-generation SSI models should enable practical time-domain analysis. The author suggests a road map – the sequence of problems to be solved to achieve a proposed level. Some of these problems have already been solved, at least in principle, but other solutions are yet to be found. The author describes the current status of his research and ideas about implementing modern computational techniques such as parallel computation.

scholarly journals Study of optimal measurement conditions for time-domain diffuse optics systems

2018 ◽  
Author(s):  
Anurag Behera ◽  
Laura Di Sieno ◽  
Antonio Pifferi ◽  
Fabrizio Martelli ◽  
Alberto Dalla Mora
Keyword(s):  
Time Domain ◽  
Diffuse Optics ◽  
Optimal Measurement

scholarly journals Performance of 6x6 mm$^2$ SiPM module for time-domain diffuse optics

2021 ◽  
pp. 1-1
Author(s):  
Anurag Behera ◽  
Fabio Acerbi ◽  
Alberto Gola ◽  
Alberto Dalla Mora ◽  
Laura Disieno
Keyword(s):  
Time Domain ◽  
Diffuse Optics

scholarly journals Coherent fluctuations in time-domain diffuse optics

APL Photonics ◽  
2020 ◽  
Vol 5 (7) ◽  
pp. 071301
Author(s):  
Lorenzo Colombo ◽  
Saeed Samaei ◽  
Pranav Lanka ◽  
Daniele Ancora ◽  
Marco Pagliazzi ◽  
...  
Keyword(s):  
Time Domain ◽  
Diffuse Optics
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