scholarly journals Development of an integrated optical coherence tomography-gas nozzle system for surgical laser ablation applications: preliminary findings of in situ spinal cord deformation due to gas flow effects

2014 ◽  
Vol 6 (1) ◽  
pp. 43 ◽  
Author(s):  
Ronnie Wong ◽  
Jamil Jivraj ◽  
Barry Vuong ◽  
Joel Ramjist ◽  
Nicole A. Dinn ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Optical Coherence Tomography ◽  
Laser Ablation ◽  
Gas Flow ◽  
Optical Coherence ◽  
Integrated Optical ◽  
Flow Effects ◽  
Gas Nozzle ◽  
Surgical Laser

Spinal cord deformation due to nozzle gas flow effects using optical coherence tomography

2015 ◽  
Author(s):  
Ronnie J. Wong ◽  
Jamil Jivraj ◽  
Barry Vuong ◽  
Joel Ramjist ◽  
Cuiru Sun ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Optical Coherence Tomography ◽  
Gas Flow ◽  
Optical Coherence ◽  
Flow Effects

In-situ Observation of Tissue Laser Ablation Using Optical Coherence Tomography

2005 ◽  
Vol 37 (13-15) ◽  
pp. 1175-1183 ◽  
Author(s):  
Masato Ohmi ◽  
Manabu Tanizawa ◽  
Atsushi Fukunaga ◽  
Masamitsu Haruna
Keyword(s):  
Optical Coherence Tomography ◽  
Laser Ablation ◽  
In Situ Observation ◽  
Optical Coherence

scholarly journals In Situ Volumetric Imaging and Analysis of FRESH 3D Bioprinted Constructs Using Optical Coherence Tomography

2021 ◽  
Author(s):  
Joshua W Tashman ◽  
Daniel J Shiwarski ◽  
Alexander Ruesch ◽  
Frederick Lanni ◽  
Jana Kainerstorfer ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Error Detection ◽  
Soft Tissues ◽  
Optical Coherence ◽  
3D Bioprinting ◽  
Volumetric Imaging ◽  
Integrated Optical ◽  
3D Architecture ◽  
3D Volume

As 3D bioprinting has grown as a fabrication technology, so too has the need for improved analytical methods to characterize these engineered constructs. This is especially challenging for soft tissues composed of hydrogels and cells as these materials readily deform, posing a barrier when trying to assess print fidelity and other properties non-destructively. Indeed, given the importance of structure-function relationships in most tissue types, establishing that the 3D architecture of the bioprinted construct matches its intended anatomic design is critical. Here we report development of a multimaterial bioprinting platform with integrated optical coherence tomography (OCT) for in situ volumetric imaging, error detection, and 3D reconstruction. While generally applicable to extrusion-based 3D bioprinting, we also report improvements to the Freeform Reversible Embedding of Suspended Hydrogels (FRESH) bioprinting process through new collagen bioink compositions, support bath optical clearing, and machine pathing. This enables high-fidelity 3D volumetric imaging with micron scale resolution over centimeter length scales, the ability to detect a range of print defect types within a 3D volume, and real-time imaging of the printing process at each print layer. These advances provide FRESH and other extrusion-based 3D bioprinting approaches with a comprehensive methodology for quality assessment that has been absent in the field to date, paving the way for translation of these engineered tissues to the clinic and ultimately to achieving regulatory approval.

scholarly journals Speckle variance optical coherence tomography of the rodent spinal cord: in vivo feasibility

2012 ◽  
Vol 3 (5) ◽  
pp. 911 ◽  
Author(s):  
David W. Cadotte ◽  
Adrian Mariampillai ◽  
Adam Cadotte ◽  
Kenneth K. C. Lee ◽  
Tim-Rasmus Kiehl ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Optical Coherence Tomography ◽  
Optical Coherence

Optical Coherence Tomography for the Detection of Laser In Situ Keratomileusis in Donor Corneas

Cornea ◽  
2003 ◽  
Vol 22 (1) ◽  
pp. 46-50 ◽  
Author(s):  
Siegfried G. Priglinger ◽  
Aljoscha S. Neubauer ◽  
Christian-Albrecht May ◽  
Claudia S. Alge ◽  
Armin H. Wolf ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Laser In Situ Keratomileusis ◽  
Optical Coherence ◽  
Donor Corneas
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