scholarly journals Determination of best Raman spectroscopy spatial offsets for transcutaneous bone quality assessments in human hands

2021 ◽  
Author(s):  
Keren Chen ◽  
Christine Massie ◽  
Hani Awad ◽  
Andrew Berger
Keyword(s):  
Raman Spectroscopy ◽  
Bone Quality ◽  
Quality Assessments ◽  
Human Hands

scholarly journals Determination of best Raman spectroscopy spatial offsets for transcutaneous bone quality assessments in human hands

2021 ◽  
Author(s):  
Keren Chen ◽  
Christine Massie ◽  
Hani A Awad ◽  
Andrew J Berger
Keyword(s):  
Raman Spectroscopy ◽  
Bone Quality ◽  
Bone Fracture ◽  
Signal To Noise Ratio ◽  
Spectral Unmixing ◽  
Absolute Amount ◽  
Signal To Noise ◽  
Noise Ratio ◽  
Quality Assessments

Spatially offset Raman spectroscopy (SORS) is able to detect bone signal transcutaneously and could assist in predicting bone fracture risk. Criteria for optimal source-detector offsets for transcutaneous human measurements, however, are not well-established. Although larger offsets yield a higher percentage of bone signal, the absolute amount of bone signal decreases. Spectral unmixing into bone, adipose, and non-adipose components was employed to quantify changes in bone signal to noise ratio across a range of offsets, and optimal offsets for phalanx and metacarpal measurements were determined. The bone signal to noise ratio was maximized at offsets ranging from 4-6 mm.

Determination of Human Coronary Artery Composition by Raman Spectroscopy

Circulation ◽  
1997 ◽  
Vol 96 (1) ◽  
pp. 99-105 ◽  
Author(s):  
James F. Brennan ◽  
Tjeerd J. Römer ◽  
Robert S. Lees ◽  
Anna M. Tercyak ◽  
John R. Kramer ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Coronary Artery ◽  
Human Coronary Artery

Multivariate Analysis Aided Surface-Enhanced Raman Spectroscopy (MVA-SERS) Multiplex Quantitative Detection of Trace Fentanyl in Illicit Drug Mixtures Using a Handheld Raman Spectrometer

2021 ◽  
pp. 000370282110329
Author(s):  
Ling Wang ◽  
Mario O. Vendrell-Dones ◽  
Chiara Deriu ◽  
Sevde Doğruer ◽  
Peter de B. Harrington ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Principal Component ◽  
Surface Enhanced Raman Spectroscopy ◽  
Quantitative Detection ◽  
Least Squares Regression ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Sers Detection ◽  
Current Screening

Recently there has been upsurge in reports that illicit seizures of cocaine and heroin have been adulterated with fentanyl. Surface-enhanced Raman spectroscopy (SERS) provides a useful alternative to current screening procedures that permits detection of trace levels of fentanyl in mixtures. Samples are solubilized and allowed to interact with aggregated colloidal nanostars to produce a rapid and sensitive assay. In this study, we present the quantitative determination of fentanyl in heroin and cocaine using SERS, using a point-and-shoot handheld Raman system. Our protocol is optimized to detect pure fentanyl down to 0.20 ± 0.06 ng/mL and can also distinguish pure cocaine and heroin at ng/mL levels. Multiplex analysis of mixtures is enabled by combining SERS detection with principal component analysis and super partial least squares regression discriminate analysis (SPLS-DA), which allow for the determination of fentanyl as low as 0.05% in simulated seized heroin and 0.10% in simulated seized cocaine samples.

Determination of ferroelastic phase transition temperature in BiVO4 by Raman spectroscopy

2021 ◽  
Vol 291 ◽  
pp. 129519
Author(s):  
Yuwaraj K. Kshetri ◽  
Bina Chaudhary ◽  
Takashi Kamiyama ◽  
Tae-Ho Kim ◽  
Federico Rosei ◽  
...  
Keyword(s):  
Phase Transition ◽  
Raman Spectroscopy ◽  
Transition Temperature ◽  
Phase Transition Temperature ◽  
Ferroelastic Phase Transition

Raman spectroscopy as a method of determination of the charge on BO in its complexes

2001 ◽  
Vol 120 (1-3) ◽  
pp. 739-740 ◽  
Author(s):  
O. Drozdova ◽  
H. Yamochi ◽  
K. Yakushi ◽  
M. Uruichi ◽  
S. Horiuchi ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Method Of Determination
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