scholarly journals Signal properties of split-spectrum amplitude decorrelation angiography for quantitative optical coherence tomography-based velocimetry

2021 ◽  
Vol 12 (10) ◽  
pp. 5955
Author(s):  
Yu Nakamichi ◽  
Kai-shih Chiu ◽  
Chia-Wei Sun
Keyword(s):  
Optical Coherence Tomography ◽  
Optical Coherence ◽  
Split Spectrum ◽  
Spectrum Amplitude

scholarly journals Split-spectrum amplitude-decorrelation angiography with optical coherence tomography

2012 ◽  
Vol 20 (4) ◽  
pp. 4710 ◽  
Author(s):  
Yali Jia ◽  
Ou Tan ◽  
Jason Tokayer ◽  
Benjamin Potsaid ◽  
Yimin Wang ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Optical Coherence ◽  
Split Spectrum ◽  
Spectrum Amplitude

Choriocapillaris and retinal vascular plexus density of diabetic eyes using split-spectrum amplitude decorrelation spectral-domain optical coherence tomography angiography

2018 ◽  
Vol 103 (4) ◽  
pp. 452-456 ◽  
Author(s):  
Felipe F Conti ◽  
Vivian L Qin ◽  
Eduardo B Rodrigues ◽  
Sumit Sharma ◽  
Aleksandra V Rachitskaya ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Diabetic Retinopathy ◽  
Proliferative Diabetic Retinopathy ◽  
Optical Coherence Tomography Angiography ◽  
Spectral Domain ◽  
Foveal Avascular Zone ◽  
Optical Coherence ◽  
Split Spectrum ◽  
Perfusion Density ◽  
Spectrum Amplitude

Background/aimsSplit-spectrum amplitude decorrelation angiography for spectral-domain optical coherence tomography has enabled detailed, non-invasive assessment of vascular flow. This study evaluates choriocapillaris and retinal capillary perfusion density (CPD) in diabetic eyes using optical coherence tomography angiography (OCTA).MethodsRecords of 136 eyes that underwent OCTA imaging at a single institution were reviewed. Eyes were grouped as non-diabetic controls (37 eyes), patients with diabetes mellitus (DM) without diabetic retinopathy (DM without DR, 31 eyes), non-proliferative diabetic retinopathy (NPDR, 41 eyes) and proliferative diabetic retinopathy (PDR, 27 eyes). Quantitative CPD analyses were performed on OCTA images for assessing perfusion density of the choriocapillaris and retinal plexus for all patients and compared between groups.ResultsEyes with NPDR and PDR showed significantly decreased choriocapillaris CPD compared with controls, while DM eyes without DR did not show significant change. Choriocapillaris whole-image CPD was decreased by 8.3% in eyes with NPDR (p<0.01) and decreased by 7.1% in eyes with PDR (p<0.01). Choriocapillaris parafoveal CPD was decreased by 8.9% in eyes with NPDR (p<0.01) and decreased by 8.2% in eyes with PDR (p<0.01). Compared with controls, only eyes with PDR showed significantly decreased retinal CPD, as well as significantly increased foveal avascular zone (FAZ) area. In those patients, retinal whole-image CPD was decreased by 9.7% (p<0.01), retinal foveal CPD was decreased by 20.5% (p<0.01) and retinal parafoveal CPD was decreased by 11.4% (p<0.01). FAZ area was increased by 50.9% (p<0.01).ConclusionsChoriocapillaris and retinal CPD are reduced in diabetic retinopathy, while FAZ area is increased in eyes with PDR. Vascular changes captured by new imaging modalities can further characterise diabetic choroidopathy.

scholarly journals Optical Coherence Tomography Angiography in Retinal Vascular Diseases and Choroidal Neovascularization

2015 ◽  
Vol 2015 ◽  
pp. 1-8 ◽  
Author(s):  
Rodolfo Mastropasqua ◽  
Luca Di Antonio ◽  
Silvio Di Staso ◽  
Luca Agnifili ◽  
Angela Di Gregorio ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Choroidal Neovascularization ◽  
Healthy Subjects ◽  
Optical Coherence Tomography Angiography ◽  
Vascular Diseases ◽  
Age Related Macular Degeneration ◽  
Foveal Avascular Zone ◽  
Optical Coherence ◽  
Age Related ◽  
Split Spectrum

Purpose. To assess the ability of optical coherence tomography-angiography (OCT-A) to show and analyze retinal vascular patterns and the choroidal neovascularization (CNV) in retinal vascular diseases.Methods. Seven eyes of seven consecutive patients with retinal vascular diseases were examined. Two healthy subjects served as controls. All eyes were scanned with the SD-OCT XR Avanti (Optovue Inc, Fremont CA, USA). Split spectrum amplitude decorrelation angiography algorithm was used to identify the blood flow within the tissue. Fluorescein angiography (FA) and indocyanine green angiography (ICGA) with Spectralis HRA + OCT (Heidelberg Engineering GmbH) were performed.Results. In healthy subjects OCT-A visualized major macular vessels and detailed capillary networks around the foveal avascular zone. Patients were affected with myopic CNV (2 eyes), age-related macular degeneration related (2), branch retinal vein occlusion (BRVO) (2), and branch retinal artery occlusion (BRAO) (1). OCT-A images provided distinct vascular patterns, distinguishing perfused and nonperfused areas in BRVO and BRAO and recognizing the presence, location, and size of CNV.Conclusions. OCT-A provides detailed images of retinal vascular plexuses and quantitative data of pathologic structures. Further studies are warranted to define the role of OCT-A in the assessment of retinovascular diseases, with respect to conventional FA and ICG-A.

scholarly journals High speed, wide velocity dynamic range Doppler optical coherence tomography (Part IV): split spectrum processing in rotary catheter probes

2014 ◽  
Vol 22 (7) ◽  
pp. 7399 ◽  
Author(s):  
Barry Vuong ◽  
Anthony M.D. Lee ◽  
Timothy W.H. Luk ◽  
Cuiru Sun ◽  
Stephen Lam ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
High Speed ◽  
Dynamic Range ◽  
Optical Coherence ◽  
Doppler Optical Coherence Tomography ◽  
Split Spectrum
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