scholarly journals Articular cartilage optical properties in the near-infrared (NIR) spectral range vary with depth and tissue integrity

2021 ◽  
Author(s):  
Bilour Khan ◽  
Iman Kafian-Attari ◽  
Ervin Nippolainen ◽  
Rubina Shaikh ◽  
Dmitry Semenov ◽  
...  
Keyword(s):  
Optical Properties ◽  
Articular Cartilage ◽  
Spectral Range ◽  
Near Infrared ◽  
Tissue Integrity

Optical properties of articular cartilage in the near-Infrared spectral range are related to its proteoglycan content

2020 ◽  
Author(s):  
Iman Kafan Attari ◽  
Dmitry V. Semenov ◽  
Ervin Nippolainen ◽  
Markku Hauta-Kasari ◽  
Juha Töyräs ◽  
...  
Keyword(s):  
Optical Properties ◽  
Articular Cartilage ◽  
Spectral Range ◽  
Near Infrared ◽  
Infrared Spectral Range ◽  
Infrared Spectral ◽  
Proteoglycan Content

Optical properties of selected native and coagulated human brain tissues in vitro in the visible and near infrared spectral range

2002 ◽  
Vol 47 (12) ◽  
pp. 2059-2073 ◽  
Author(s):  
A N Yaroslavsky ◽  
P C Schulze ◽  
I V Yaroslavsky ◽  
R Schober ◽  
F Ulrich ◽  
...  
Keyword(s):  
Optical Properties ◽  
Human Brain ◽  
Spectral Range ◽  
Near Infrared ◽  
Infrared Spectral Range ◽  
Infrared Spectral ◽  
Brain Tissues

Optical properties of normal and cancerous human skin in the visible and near-infrared spectral range

2006 ◽  
Vol 11 (6) ◽  
pp. 064026 ◽  
Author(s):  
Elena Salomatina ◽  
Brian Jiang ◽  
John Novak ◽  
Anna N. Yaroslavsky
Keyword(s):  
Optical Properties ◽  
Human Skin ◽  
Spectral Range ◽  
Near Infrared ◽  
Infrared Spectral Range ◽  
Infrared Spectral

scholarly journals Spectral Optical Properties of Rabbit Brain Cortex Between 200 and 1000 nm

2021 ◽  
Author(s):  
Tânia Gonçalves ◽  
Inês Soraia Martins ◽  
Hugo Silva ◽  
Valery Tuchin ◽  
Luís Oliveira
Keyword(s):  
Optical Properties ◽  
Spectral Range ◽  
Brain Cortex ◽  
Near Infrared ◽  
Ex Vivo ◽  
Biological Tissues ◽  
Rabbit Brain ◽  
Rabbit Brain Cortex ◽  
Infrared Spectral ◽  
The Brain

The knowledge of the optical properties of biological tissues in a wide spectral range is highly important for the development of noninvasive diagnostic or treatment procedures. The absorption coefficient is one of those properties, from which various information about tissue components can be retrieved. Using transmittance and reflectance spectral measurements acquired from ex vivo rabbit brain cortex samples, allowed to calculate its optical properties in the ultraviolet to the near infrared spectral range. Melanin and lipofuscin, the two pigments that are related to the ageing of tissues and cells were identified in the cortex absorption. By subtracting the absorption of these pigments from the absorption of the brain cortex, it was possible to evaluate the true ratios for the DNA/RNA and hemoglobin bands in the cortex – 12.33 fold (at 260 nm), 12.02 fold (at 411 nm) and 4.47 fold (at 555 nm). Due to the fact that the accumulation of melanin and lipofuscin increases with the ageing of the brain tissues and are related to the degeneration of neurons and their death, further studies should be performed to evaluate the evolution of pigment accumulation in the brain to prevent the development of Alzheimer, Parkinson and stroke pathologies in the brain.

scholarly journals Spectral Optical Properties of Rabbit Brain Cortex between 200 and 1000 nm

Photochem ◽  
2021 ◽  
Vol 1 (2) ◽  
pp. 190-208
Author(s):  
Tânia M. Gonçalves ◽  
Inês S. Martins ◽  
Hugo F. Silva ◽  
Valery V. Tuchin ◽  
Luís M. Oliveira
Keyword(s):  
Optical Properties ◽  
Spectral Range ◽  
Brain Cortex ◽  
Near Infrared ◽  
Biological Tissues ◽  
Optical Methods ◽  
Brain Diseases ◽  
Rabbit Brain ◽  
Rabbit Brain Cortex ◽  
The Brain

The knowledge of the optical properties of biological tissues in a wide spectral range is highly important for the development of noninvasive diagnostic or treatment procedures. The absorption coefficient is one of those properties, from which various information about tissue components can be retrieved. Using transmittance and reflectance spectral measurements acquired from ex vivo rabbit brain cortex samples allowed to calculate its optical properties in the ultraviolet to the near infrared spectral range. Melanin and lipofuscin, the two pigments that are related to the aging of tissues and cells were identified in the cortex absorption. By subtracting the absorption of these pigments from the absorption of the brain cortex, it was possible to evaluate the true ratios for the DNA/RNA and hemoglobin bands in the cortex—12.33-fold (at 260 nm), 12.02-fold (at 411 nm) and 4.47-fold (at 555 nm). Since melanin and lipofuscin accumulation increases with the aging of the brain tissues and are related to the degeneration of neurons and their death, further studies should be performed to evaluate the evolution of pigment accumulation in the brain, so that new optical methods can be developed to aid in the diagnosis and monitoring of brain diseases.

Optical properties of blood in the near-infrared spectral range

1996 ◽  
Author(s):  
Anna N. Yaroslavsky ◽  
Ilya V. Yaroslavsky ◽  
Thomas Goldbach ◽  
Hans-Joachim Schwarzmaier
Keyword(s):  
Optical Properties ◽  
Spectral Range ◽  
Near Infrared ◽  
Infrared Spectral Range ◽  
Infrared Spectral

Resolving the Near-Infrared Spectrum of Articular Cartilage

Cartilage ◽  
2021 ◽  
pp. 194760352110354
Author(s):  
Isaac O. Afara ◽  
Adekunle Oloyede
Keyword(s):  
Articular Cartilage ◽  
Spectral Range ◽  
Near Infrared ◽  
Physiological State ◽  
Arthroscopic Surgery ◽  
Unmet Need ◽  
Solid Matrix ◽  
Spectroscopic Techniques ◽  
Native Cartilage ◽  
Matrix Components

Objective Spectroscopic techniques, such as near-infrared (NIR) spectroscopy, are gaining significant research interest for characterizing connective tissues, particularly articular cartilage, because there is still a largely unmet need for rapid, accurate and objective methods for assessing tissue integrity in real-time during arthroscopic surgery. This study aims to identify the NIR spectral range that is optimal for characterizing cartilage integrity by ( a) identifying the contribution of its major constituents (collagen and proteoglycans) to its overall spectrum using proxy constituent models and ( b) determining constituent-specific spectral contributions that can be used for assessment of cartilage in its physiological state. Design The NIR spectra of cartilage matrix constituent models were measured and compared with specific molecular components of organic compounds in the NIR spectral range in order to identify their bands and molecular assignments. To verify the identified bands, spectra of the model compounds were compared with those of native cartilage. Since water obscures some bands in the NIR range, spectral measurements of the native cartilage were conducted under conditions of decreasing water content to amplify features of the solid matrix components. The identified spectral bands were then compared and examined in the resulting spectra of the intact cartilage samples. Results As water was progressively eliminated from cartilage, the specific contribution of the different matrix components was observed to correspond with those identified from the proxy cartilage component models. Conclusion Spectral peaks in the regions 5500 to 6250 cm−1 and 8100 to 8600 cm−1 were identified to be effective for characterizing cartilage proteoglycan and collagen contents, respectively.

scholarly journals Optical properties of native and coagulated lamb brain tissues in vitro in the visible and near-infrared spectral range

2006 ◽  
Author(s):  
Korhan Özer ◽  
Özgüncem Bozkulak ◽  
Haşim Özgür Tabakoğlu ◽  
Adnan Kurt ◽  
Murat Gülsoy
Keyword(s):  
Optical Properties ◽  
Spectral Range ◽  
Near Infrared ◽  
Infrared Spectral Range ◽  
Infrared Spectral ◽  
Brain Tissues
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