scholarly journals Polarimetric imaging of the human brain to determine the orientation and degree of alignment of nerve fiber bundles

2021 ◽  
Author(s):  
Arushi Jain ◽  
Leonie Ulrich ◽  
Michael Jaeger ◽  
PHILIPPE SCHUCHT ◽  
Martin Frenz ◽  
...  
Keyword(s):  
Human Brain ◽  
Nerve Fiber ◽  
Fiber Bundles ◽  
Polarimetric Imaging

Localization of nerve fiber bundles by polarization-sensitive optical coherence tomography

2008 ◽  
Vol 174 (1) ◽  
pp. 82-90 ◽  
Author(s):  
Haruo Nakaji ◽  
Nobuo Kouyama ◽  
Yoshihiro Muragaki ◽  
Yoriko Kawakami ◽  
Hiroshi Iseki
Keyword(s):  
Optical Coherence Tomography ◽  
Nerve Fiber ◽  
Fiber Bundles ◽  
Optical Coherence

scholarly journals Scatterometry Measurements With Scattered Light Imaging Enable New Insights Into the Nerve Fiber Architecture of the Brain

2021 ◽  
Vol 15 ◽  
Author(s):  
Miriam Menzel ◽  
Marouan Ritzkowski ◽  
Jan A. Reuter ◽  
David Gräßel ◽  
Katrin Amunts ◽  
...  
Keyword(s):  
Human Brain ◽  
Nerve Fiber ◽  
Brain Tissue ◽  
Scattered Light ◽  
Polar Angle ◽  
Nerve Fibers ◽  
Fiber Architecture ◽  
Whole Brain ◽  
Tissue Samples ◽  
The Brain

The correct reconstruction of individual (crossing) nerve fibers is a prerequisite when constructing a detailed network model of the brain. The recently developed technique Scattered Light Imaging (SLI) allows the reconstruction of crossing nerve fiber pathways in whole brain tissue samples with micrometer resolution: the individual fiber orientations are determined by illuminating unstained histological brain sections from different directions, measuring the transmitted scattered light under normal incidence, and studying the light intensity profiles of each pixel in the resulting image series. So far, SLI measurements were performed with a fixed polar angle of illumination and a small number of illumination directions, providing only an estimate of the nerve fiber directions and limited information about the underlying tissue structure. Here, we use a display with individually controllable light-emitting diodes to measure the full distribution of scattered light behind the sample (scattering pattern) for each image pixel at once, enabling scatterometry measurements of whole brain tissue samples. We compare our results to coherent Fourier scatterometry (raster-scanning the sample with a non-focused laser beam) and previous SLI measurements with fixed polar angle of illumination, using sections from a vervet monkey brain and human optic tracts. Finally, we present SLI scatterometry measurements of a human brain section with 3 μm in-plane resolution, demonstrating that the technique is a powerful approach to gain new insights into the nerve fiber architecture of the human brain.

Imaging retinal nerve fiber bundles at ultrahigh-speed and ultrahigh-resolution using OCT with adaptive optics

2010 ◽  
Author(s):  
Omer Pars Kocaoglu ◽  
Barry Cense ◽  
Qiang Wang ◽  
Jeremy Bruestle ◽  
Jason Besecker ◽  
...  
Keyword(s):  
Nerve Fiber ◽  
Adaptive Optics ◽  
Fiber Bundles ◽  
Ultrahigh Resolution ◽  
Retinal Nerve Fiber

scholarly journals Imaging retinal nerve fiber bundles using optical coherence tomography with adaptive optics

2011 ◽  
Vol 51 (16) ◽  
pp. 1835-1844 ◽  
Author(s):  
Omer P. Kocaoglu ◽  
Barry Cense ◽  
Ravi S. Jonnal ◽  
Qiang Wang ◽  
Sangyeol Lee ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Nerve Fiber ◽  
Adaptive Optics ◽  
Fiber Bundles ◽  
Optical Coherence ◽  
Retinal Nerve Fiber

scholarly journals Adaptive Optics Imaging of Healthy and Abnormal Regions of Retinal Nerve Fiber Bundles of Patients With Glaucoma

2015 ◽  
Vol 56 (1) ◽  
pp. 674-681 ◽  
Author(s):  
M. F. Chen ◽  
T. Y. P. Chui ◽  
P. Alhadeff ◽  
R. B. Rosen ◽  
R. Ritch ◽  
...  
Keyword(s):  
Nerve Fiber ◽  
Adaptive Optics ◽  
Fiber Bundles ◽  
Adaptive Optics Imaging ◽  
Retinal Nerve Fiber

scholarly journals Customizing Perimetric Locations Based on En Face Images of Retinal Nerve Fiber Bundles With Glaucomatous Damage

2018 ◽  
Vol 7 (2) ◽  
pp. 5 ◽  
Author(s):  
Muhammed S. Alluwimi ◽  
William H. Swanson ◽  
Victor E. Malinovsky ◽  
Brett J. King
Keyword(s):  
Nerve Fiber ◽  
Fiber Bundles ◽  
Glaucomatous Damage ◽  
Face Images ◽  
En Face ◽  
Retinal Nerve Fiber

scholarly journals High-Resolution Imaging of Retinal Nerve Fiber Bundles in Glaucoma Using Adaptive Optics Scanning Laser Ophthalmoscopy

2013 ◽  
Vol 155 (5) ◽  
pp. 870-881.e3 ◽  
Author(s):  
Kohei Takayama ◽  
Sotaro Ooto ◽  
Masanori Hangai ◽  
Naoko Ueda-Arakawa ◽  
Sachiko Yoshida ◽  
...  
Keyword(s):  
High Resolution ◽  
Nerve Fiber ◽  
Adaptive Optics ◽  
Fiber Bundles ◽  
Scanning Laser ◽  
High Resolution Imaging ◽  
Scanning Laser Ophthalmoscopy ◽  
Resolution Imaging ◽  
Retinal Nerve Fiber
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