scholarly journals Centimeter-scale wide-field-of-view laser-scanning photoacoustic microscopy for subcutaneous microvasculature in vivo

2021 ◽  
Author(s):  
Tangyun Liao ◽  
Yuan Liu ◽  
Junwei Wu ◽  
Lijun Deng ◽  
yu deng ◽  
...  
Keyword(s):  
Laser Scanning ◽  
Field Of View ◽  
Wide Field ◽  
Photoacoustic Microscopy ◽  
Wide Field Of View

3D wide field-of-view Gabor-domain optical coherence microscopy advancing real-time in-vivo imaging and metrology

2017 ◽  
Author(s):  
Cristina Canavesi ◽  
Andrea Cogliati ◽  
Adam Hayes ◽  
Patrice Tankam ◽  
Anand Santhanam ◽  
...  
Keyword(s):  
Real Time ◽  
In Vivo Imaging ◽  
Field Of View ◽  
Wide Field ◽  
Optical Coherence ◽  
Optical Coherence Microscopy ◽  
Wide Field Of View ◽  
Gabor Domain

Mosaicing for fast wide-field-of-view optical-resolution photoacoustic microscopy

2012 ◽  
Author(s):  
Peng Shao ◽  
Wei Shi ◽  
Ryan K. Chee ◽  
Alexander Forbrich ◽  
Roger J. Zemp
Keyword(s):  
Optical Resolution ◽  
Field Of View ◽  
Wide Field ◽  
Photoacoustic Microscopy ◽  
Wide Field Of View

scholarly journals Performance Comparison of Feature Generation Algorithms for Mosaic Photoacoustic Microscopy

Photonics ◽  
2021 ◽  
Vol 8 (9) ◽  
pp. 352
Author(s):  
Thanh Dat Le ◽  
Seong Young Kwon ◽  
Changho Lee
Keyword(s):  
Performance Comparison ◽  
Field Of View ◽  
Successful Implementation ◽  
Wide Field ◽  
Photoacoustic Microscopy ◽  
Feature Generation ◽  
Wide Field Of View ◽  
Matching Efficiency ◽  
Merging Process ◽  
Mouse Ear

Mosaic imaging is a computer vision process that is used for merging multiple overlapping imaging patches into a wide-field-of-view image. To achieve a wide-field-of-view photoacoustic microscopy (PAM) image, the limitations of the scan range of PAM require a merging process, such as marking the location of patches or merging overlapping areas between adjacent images. By using the mosaic imaging process, PAM shows a larger field view of targets and preserves the quality of the spatial resolution. As an essential process in mosaic imaging, various feature generation methods have been used to estimate pairs of image locations. In this study, various feature generation algorithms were applied and analyzed using a high-resolution mouse ear PAM image dataset to achieve and optimize a mosaic imaging process for wide-field PAM imaging. We compared the performance of traditional and deep learning feature generation algorithms by estimating the processing time, the number of matches, good matching ratio, and matching efficiency. The analytic results indicate the successful implementation of wide-field PAM images, realized by applying suitable methods to the mosaic PAM imaging process.

Adaptive glasses wavefront sensorless full-field OCT for high-resolution in-vivo retinal imaging over a wide field-of-view

2021 ◽  
Author(s):  
Yao Cai ◽  
Jules Scholler ◽  
Kassandra Groux ◽  
Olivier Thouvenin ◽  
Claude Boccara ◽  
...  
Keyword(s):  
High Resolution ◽  
Retinal Imaging ◽  
Field Of View ◽  
Wide Field ◽  
Full Field ◽  
Wide Field Of View

scholarly journals High-resolution wide-field human brain tumor margin detection and in vivo murine neuroimaging

2018 ◽  
Author(s):  
Derek Yecies ◽  
Orly Liba ◽  
Elliott SoRelle ◽  
Rebecca Dutta ◽  
Edwin Yuan ◽  
...  
Keyword(s):  
Brain Tumor ◽  
White Matter ◽  
Ex Vivo ◽  
Field Of View ◽  
Low Grade ◽  
Wide Field ◽  
Tumor Margin ◽  
Wide Field Of View ◽  
Margin Detection

AbstractCurrent in vivo neuroimaging techniques provide limited field of view or spatial resolution and often require exogenous contrast. These limitations prohibit detailed structural imaging across wide fields of view and hinder intraoperative tumor margin detection. Here we present a novel neuroimaging technique, speckle-modulating optical coherence tomography (SM-OCT), which allows us to image the brains of live mice and ex vivo human samples with unprecedented resolution and wide field of view using only endogenous contrast. The increased effective resolution provided by speckle elimination reveals white matter fascicles and cortical layer architecture in the brains of live mice. To our knowledge, the data reported herein represents the highest resolution imaging of murine white matter structure achieved in vivo across a wide field of view of several millimeters. When applied to an orthotopic murine glioblastoma xenograft model, SM-OCT readily identifies brain tumor margins with near single-cell resolution. SM-OCT of ex vivo human temporal lobe tissue reveals fine structures including cortical layers and myelinated axons. Finally, when applied to an ex vivo sample of a low-grade glioma resection margin, SM-OCT is able to resolve the brain tumor margin. Based on these findings, SM-OCT represents a novel approach for intraoperative tumor margin detection and in vivo neuroimaging.

STM studies of crystal growth

1991 ◽  
Vol 49 ◽  
pp. 374-375
Author(s):  
M. G. Lagally
Keyword(s):  
Crystal Growth ◽  
Molecular Beam ◽  
Chemical Vapor ◽  
Sputter Deposition ◽  
Field Of View ◽  
Scanning Tunneling ◽  
Wide Field ◽  
Tunneling Microscopy ◽  
Wide Field Of View ◽  
The One

It has been recognized since the earliest days of crystal growth that kinetic processes of all Kinds control the nature of the growth. As the technology of crystal growth has become ever more refined, with the advent of such atomistic processes as molecular beam epitaxy, chemical vapor deposition, sputter deposition, and plasma enhanced techniques for the creation of “crystals” as little as one or a few atomic layers thick, multilayer structures, and novel materials combinations, the need to understand the mechanisms controlling the growth process is becoming more critical. Unfortunately, available techniques have not lent themselves well to obtaining a truly microscopic picture of such processes. Because of its atomic resolution on the one hand, and the achievable wide field of view on the other (of the order of micrometers) scanning tunneling microscopy (STM) gives us this opportunity. In this talk, we briefly review the types of growth kinetics measurements that can be made using STM. The use of STM for studies of kinetics is one of the more recent applications of what is itself still a very young field.

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