scholarly journals Optical coherence tomography and fluorescence microscopy dual-modality imaging for in vivo single-cell tracking with nanowire lasers

2020 ◽  
Vol 11 (7) ◽  
pp. 3659
Author(s):  
Xuzhou Li ◽  
Wei Zhang ◽  
William Y. Wang ◽  
Xiaoqin Wu ◽  
Yanxiu Li ◽  
...  
2020 ◽  
Vol 245 (4) ◽  
pp. 342-347 ◽  
Author(s):  
Arash Dadkhah ◽  
Shuliang Jiao

We have developed a multimodal imaging system, which integrated optical resolution photoacoustic microscopy, optical coherence tomography, optical coherence tomography angiography, and confocal fluorescence microscopy in one platform. The system is able to image complementary features of a biological sample by combining different contrast mechanisms. We achieved fast imaging and large field of view by combining optical scanning with mechanical scanning, similar to our previous publication. We have demonstrated the capability of the multimodal imaging system by imaging a mouse ear in vivo. Impact statement Photoacoustic microscopy-based multimodal imaging technology can provide high-resolution complementary information for biological tissues in vivo. It will potentially bring significant impact on the research and diagnosis of diseases by providing combined structural and functional information.


2015 ◽  
Vol 6 (9) ◽  
pp. 3163 ◽  
Author(s):  
Behrooz Zabihian ◽  
Jessika Weingast ◽  
Mengyang Liu ◽  
Edward Zhang ◽  
Paul Beard ◽  
...  

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