scholarly journals Phase-sensitive imaging of the outer retina using optical coherence tomography and adaptive optics

2011 ◽  
Vol 3 (1) ◽  
pp. 104 ◽  
Author(s):  
Ravi S. Jonnal ◽  
Omer P. Kocaoglu ◽  
Qiang Wang ◽  
Sangyeol Lee ◽  
Donald T. Miller
Keyword(s):  
Optical Coherence Tomography ◽  
Adaptive Optics ◽  
Optical Coherence ◽  
Outer Retina ◽  
Phase Sensitive

scholarly journals Interpretation of anatomic correlates of outer retinal bands in optical coherence tomography

2021 ◽  
pp. 153537022110226
Author(s):  
Xincheng Yao ◽  
Taeyoon Son ◽  
Tae-Hoon Kim ◽  
David Le
Keyword(s):  
Optical Coherence Tomography ◽  
Adaptive Optics ◽  
Outer Segment ◽  
Pigment Epithelium ◽  
Retinal Pigment ◽  
Disease Diagnosis ◽  
Eye Disease ◽  
Optical Coherence ◽  
Outer Retina ◽  
The Third

By providing the sectioning capability to differentiate individual retinal layers, optical coherence tomography (OCT) is revolutionizing eye disease diagnosis and treatment evaluation. A better understanding of the hyper- and hypo-reflective bands in retinal OCT is essential for accurate interpretation of clinical outcomes. In this article, we summarize the interpretations of clinical OCT and adaptive optics (AO) OCT (AO-OCT) of the outer retina in the human eye, and briefly review OCT investigation of the outer retina in animal models. Quantitative analysis of outer retinal OCT bands is compared to established parameters of retinal histology. The literature review and comparative analysis support that both inner/outer segment (IS/OS) junction and IS ellipsoid zone nonexclusively contribute to the second band; and OS, OS tips, and retinal pigment epithelium apical processes contribute to the third band in conventional OCT. In contrast, AO-OCT might predominantly detect the IS/OS junction and OS tip signals at the second and third bands due to its improved sectioning capability and possible AO effect on the sensitivities for recording ballistic and diffusive photons from different regions of the outer retina.

scholarly journals Inter-relationship between retinal and choroidal vasculatures using optical coherence tomography angiography in normal eyes

2018 ◽  
Vol 30 (1) ◽  
pp. 48-57 ◽  
Author(s):  
Jaeryung Oh ◽  
Daniel Jinhag Baik ◽  
Jaemoon Ahn
Keyword(s):  
Optical Coherence Tomography ◽  
Layer Thickness ◽  
Optical Coherence Tomography Angiography ◽  
Macular Thickness ◽  
Vascular Density ◽  
Inner Plexiform Layer ◽  
Central Macular Thickness ◽  
Optical Coherence ◽  
Outer Retina ◽  
Capillary Plexus

Purpose: To quantify vascular and structural macular variables in healthy eyes and to investigate correlations between these variables and age using optical coherence tomography angiography. Materials and methods: A total of 261 eyes of 261 subjects with normal fundus were included. Central macular thickness, ganglion cell layer to inner plexiform layer thickness, outer retina layer thickness, subfoveal choroidal thickness, and choroidal vascularity index were measured using optical coherence tomography. Foveal avascular zone area, vascular density, and flow void area were measured using optical coherence tomography angiography. Results: Vascular density in the superficial capillary plexus was correlated with central macular thickness, ganglion cell layer to inner plexiform layer thickness, and outer retina layer thickness ( P < 0.001, P = 0.004, and P < 0.001, respectively). Vascular density in the deep capillary plexus was correlated with central macular thickness and outer retina layer thickness ( P = 0.003 and P = 0.001, respectively). Vascular density of choriocapillaris was correlated with vascular density of superficial capillary plexus and deep capillary plexus ( P < 0.001 and P = 0.001, respectively). Conclusion: Vascular density of choriocapillaris varies with retinal vascular density rather than the structure of choroid using optical coherence tomography angiography. In contrast, retinal vascular density changes as the retinal structure. Our results provide more information about the relationship between retina and choroid.

scholarly journals Depth profiling of photothermal compound concentrations using phase sensitive optical coherence tomography

2011 ◽  
Vol 16 (12) ◽  
pp. 126003 ◽  
Author(s):  
Guangying Guan ◽  
Roberto Reif ◽  
Zhihong Huang ◽  
Ruikang K. Wang
Keyword(s):  
Optical Coherence Tomography ◽  
Depth Profiling ◽  
Optical Coherence ◽  
Phase Sensitive

Phase-sensitive interferometry in optical coherence tomography

2001 ◽  
Author(s):  
Maciej Wojtkowski ◽  
Adolf F. Fercher ◽  
Rainer Leitgeb
Keyword(s):  
Optical Coherence Tomography ◽  
Optical Coherence ◽  
Phase Sensitive

scholarly journals Bulk-phase-error correction for phase-sensitive signal processing of optical coherence tomography

2020 ◽  
Vol 11 (10) ◽  
pp. 5886
Author(s):  
Kensuke Oikawa ◽  
Daisuke Oida ◽  
Shuichi Makita ◽  
Yoshiaki Yasuno
Keyword(s):  
Signal Processing ◽  
Optical Coherence Tomography ◽  
Error Correction ◽  
Phase Error ◽  
Bulk Phase ◽  
Optical Coherence ◽  
Phase Sensitive

Optical Coherence Tomography and Glaucoma

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Alexi Geevarghese ◽  
Gadi Wollstein ◽  
Hiroshi Ishikawa ◽  
Joel S. Schuman
Keyword(s):  
Optical Coherence Tomography ◽  
Adaptive Optics ◽  
Imaging Modality ◽  
Annual Review ◽  
Publication Date ◽  
Optical Coherence ◽  
Swept Source ◽  
Diagnosis And Management ◽  
Spectral Domain Oct ◽  
Glaucoma Diagnosis

Early detection and monitoring are critical to the diagnosis and management of glaucoma, a progressive optic neuropathy that causes irreversible blindness. Optical coherence tomography (OCT) has become a commonly utilized imaging modality that aids in the detection and monitoring of structural glaucomatous damage. Since its inception in 1991, OCT has progressed through multiple iterations, from time-domain OCT, to spectral-domain OCT, to swept-source OCT, all of which have progressively improved the resolution and speed of scans. Even newer technological advancements and OCT applications, such as adaptive optics, visible-light OCT, and OCT-angiography, have enriched the use of OCT in the evaluation of glaucoma. This article reviews current commercial and state-of-the-art OCT technologies and analytic techniques in the context of their utility for glaucoma diagnosis and management, as well as promising future directions. Expected final online publication date for the Annual Review of Vision Science, Volume 7 is September 2021. Please see http://www.annualreviews.org/page/journal/pubdates for revised estimates.

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