scholarly journals Epidural needle with embedded optical fibers for spectroscopic differentiation of tissue: ex vivo feasibility study

2011 ◽  
Vol 2 (6) ◽  
pp. 1452 ◽  
Author(s):  
Adrien E. Desjardins ◽  
Benno H.W. Hendriks ◽  
Marjolein van der Voort ◽  
Rami Nachabé ◽  
Walter Bierhoff ◽  
...  
Keyword(s):  
Feasibility Study ◽  
Optical Fibers ◽  
Ex Vivo ◽  
Epidural Needle

scholarly journals A New Technique to Assist Epidural Needle Placement

2010 ◽  
Vol 112 (5) ◽  
pp. 1128-1135 ◽  
Author(s):  
Chien-Kun Ting ◽  
Mei-Yung Tsou ◽  
Pin-Tarng Chen ◽  
Kuang-Yi Chang ◽  
M. Susan Mandell ◽  
...  
Keyword(s):  
Real Time ◽  
Optical Fibers ◽  
Epidural Space ◽  
Optical Method ◽  
Porcine Model ◽  
Ligamentum Flavum ◽  
Ex Vivo ◽  
Epidural Needle ◽  
Time Data ◽  
532 Nm

Background Up to 10% of epidurals fail due to incorrect catheter placement. We describe a novel optical method to assist epidural catheter insertion in a porcine model. Methods Optical emissions were tested on ex vivo tissues from porcine paravertebral tissues to identify optical reflective spectra. The wavelengths of 650 and 532 nm differentiated epidural space from the ligamentum flavum. We then used a hollow stylet that contained optical fibers to place epidural needles in anesthetized pigs. Real-time data were displayed on an oscilloscope and stored for analysis. A total of 50 punctures were done in four laboratory pigs. Data were expressed as mean +/- SD. Results Paired t test shows significant optical differences between the epidural space and the ligamentum flavum at both 650 nm (P < 0.001) and 532 nm (P = 0.014). Mean magnitudes for 650 nm, 532 nm, and their ratio were 3.565 +/- 0.194, 2.542 +/- 0.145, and 0.958 +/- 0.172 at epidural space and 3.842 +/- 0.191, 2.563 +/- 0.131, and 1.228 +/- 0.244 at ligamentum flavum, respectively. There were no differences in the optical characteristics of the ligamentum flavum and epidural space at different levels in the lumbar and thoracic region (two-way ANOVA P > 0.05). Conclusions This is the first study to introduce a new optical method to localize epidural space in a porcine model. Epidural space could be identified by the changes in the reflective pattern of light emitted at 650 nm, which were specific for the ligamentum flavum and dural tissue. Real-time optical information successfully guided a modified Tuohy needle into the epidural space.

Endoscopic slipknot clip suturing method: an ex vivo feasibility study (with video)

2016 ◽  
Vol 83 (2) ◽  
pp. 447-450 ◽  
Author(s):  
Toshihiro Nishizawa ◽  
Toshio Uraoka ◽  
Seiji Sagara ◽  
Hidekazu Suzuki ◽  
Teppei Akimoto ◽  
...  
Keyword(s):  
Feasibility Study ◽  
Ex Vivo

scholarly journals Trans-cranial focused ultrasound without hair shaving: feasibility study in an ex vivo cadaver model

2013 ◽  
Vol 1 (1) ◽  
pp. 24 ◽  
Author(s):  
Matthew DC Eames ◽  
Arik Hananel ◽  
John W Snell ◽  
Neal F Kassell ◽  
Jean-Francois Aubry
Keyword(s):  
Feasibility Study ◽  
Focused Ultrasound ◽  
Ex Vivo

Shape sensing of an epidural needle through a network of nanoparticles-doped optical fibers

2021 ◽  
Author(s):  
Aizhan Issatayeva ◽  
Aida Amantayeva ◽  
Wilfried Blanc ◽  
Carlo Molardi ◽  
Daniele Tosi
Keyword(s):  
Optical Fibers ◽  
Epidural Needle ◽  
Shape Sensing

512 Stem cell sampling from the first trimester fetus for prenatal ex-vivo gene therapy: Feasibility study

2001 ◽  
Vol 185 (6) ◽  
pp. S221
Author(s):  
Daniel Surbek ◽  
Alan Young ◽  
Andreina Schoeberlein ◽  
Enrico Danzer ◽  
Lisbeth Dudler ◽  
...  
Keyword(s):  
Gene Therapy ◽  
Stem Cell ◽  
Feasibility Study ◽  
Ex Vivo ◽  
First Trimester ◽  
Ex Vivo Gene Therapy

Feasibility study for distributed dose monitoring in ionizing radiation environments with standard and custom-made optical fibers

2002 ◽  
Author(s):  
Marco Van Uffelen ◽  
Francis Berghmans ◽  
Benoit Brichard ◽  
Paul Borgermans ◽  
Marc C. Decreton
Keyword(s):  
Ionizing Radiation ◽  
Feasibility Study ◽  
Optical Fibers ◽  
Dose Monitoring ◽  
Custom Made

scholarly journals Real‐time ex vivo perfusion of human lymph nodes invaded by cancer (REPLICANT): a feasibility study

2019 ◽  
Vol 250 (3) ◽  
pp. 262-274 ◽  
Author(s):  
Rachel Barrow‐McGee ◽  
Julia Procter ◽  
Julie Owen ◽  
Natalie Woodman ◽  
Cristina Lombardelli ◽  
...  
Keyword(s):  
Lymph Nodes ◽  
Real Time ◽  
Feasibility Study ◽  
Ex Vivo ◽  
Ex Vivo Perfusion

Wireless Robotic Capsule for Releasing Bioadhesive Patches in the Gastrointestinal Tract

2013 ◽  
Vol 8 (1) ◽  
Author(s):  
Claudio Quaglia ◽  
Selene Tognarelli ◽  
Edoardo Sinibaldi ◽  
Nicodemo Funaro ◽  
Paolo Dario ◽  
...  
Keyword(s):  
Gastrointestinal Tract ◽  
Minimally Invasive ◽  
Adhesion Strength ◽  
Feasibility Study ◽  
Ex Vivo ◽  
Release Mechanism ◽  
Present System ◽  
Gi Tract ◽  
Main Application ◽  
Porcine Tissue

A novel, miniature wireless robotic capsule for releasing bioadhesive patches in the gastrointestinal (GI) tract was designed, fabricated, and preliminarily tested. In particular, the assembled prototype was successfully navigated in a GI phantom, up to a target site where the release mechanism was verified. Then, deployment of a bioadhesive patch onto ex vivo porcine tissue was accomplished, and patch adhesion strength was verified. The main application of the present system is the deployment of anchoring patches for miniature robotic modules to be operated in the targeted anatomical domain. Such an innovative application stems from the wise blend of robotics and bioadhesion. Obtained results, which are consistent with previous investigations by the group, confirm the viability of the adopted bioadhesives for the envisaged anchoring tasks. The present feasibility study complies with the spirit of minimally invasive, wireless diagnosis, and therapy, and provides a preliminary contribution for their advancement.

Detection of Hepatic Fibrosis in Ex Vivo Liver Samples Using an Open-Photoacoustic-Cell Method: Feasibility Study

2015 ◽  
Vol 36 (9) ◽  
pp. 2410-2416
Author(s):  
S. Stolik ◽  
D. A. Fabila ◽  
J. M. de la Rosa ◽  
G. Escobedo ◽  
K. Suárez-Álvarez ◽  
...  
Keyword(s):  
Hepatic Fibrosis ◽  
Feasibility Study ◽  
Ex Vivo ◽  
Photoacoustic Cell ◽  
Open Photoacoustic Cell ◽  
Cell Method
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