scholarly journals Improved bioluminescence and fluorescence reconstruction algorithms using diffuse optical tomography, normalized data, and optimized selection of the permissible source region

2010 ◽  
Vol 2 (1) ◽  
pp. 169 ◽  
Author(s):  
Mohamed A. Naser ◽  
Michael S. Patterson
Keyword(s):  
Source Region ◽  
Optical Tomography ◽  
Diffuse Optical Tomography ◽  
Reconstruction Algorithms ◽  
Selection Of

scholarly journals Improvement of absorption and scattering discrimination by selection of sensitive points on temporal profile in diffuse optical tomography

2011 ◽  
Vol 19 (13) ◽  
pp. 12843 ◽  
Author(s):  
Farouk Nouizi ◽  
Murielle Torregrossa ◽  
Renee Chabrier ◽  
Patrick Poulet
Keyword(s):  
Optical Tomography ◽  
Diffuse Optical Tomography ◽  
Temporal Profile ◽  
Selection Of

Optimal selection of frequencies for Diffuse Optical Tomography

2000 ◽  
Author(s):  
Vasilis Ntziachristos ◽  
Joe Culver ◽  
Monica Holboke ◽  
A.G. Yodh ◽  
Britton Chance
Keyword(s):  
Optical Tomography ◽  
Diffuse Optical Tomography ◽  
Optimal Selection ◽  
Selection Of

scholarly journals Near-Infrared Diffuse Optical Tomography

2002 ◽  
Vol 18 (5-6) ◽  
pp. 313-337 ◽  
Author(s):  
A. H. Hielscher ◽  
A. Y. Bluestone ◽  
G. S. Abdoulaev ◽  
A. D. Klose ◽  
J. Lasker ◽  
...  
Keyword(s):  
Near Infrared ◽  
Imaging Modality ◽  
Low Cost ◽  
Optical Tomography ◽  
Diffuse Optical Tomography ◽  
Biological Tissues ◽  
Body Parts ◽  
Reconstruction Algorithms ◽  
Cross Sectional ◽  
Magnetic Resonance Imaging Mri

Diffuse optical tomography (DOT) is emerging as a viable new biomedical imaging modality. Using near-infrared (NIR) light, this technique probes absorption as well as scattering properties of biological tissues. First commercial instruments are now available that allow users to obtain cross-sectional and volumetric views of various body parts. Currently, the main applications are brain, breast, limb, joint, and fluorescence/bioluminescence imaging. Although the spatial resolution is limited when compared with other imaging modalities, such as magnetic resonance imaging (MRI) or X-ray computerized tomography (CT), DOT provides access to a variety of physiological parameters that otherwise are not accessible, including sub-second imaging of hemodynamics and other fast-changing processes. Furthermore, DOT can be realized in compact, portable instrumentation that allows for bedside monitoring at relatively low cost. In this paper, we present an overview of current state-of-the -art technology, including hardware and image-reconstruction algorithms, and focus on applications in brain and joint imaging. In addition, we present recent results of work on optical tomographic imaging in small animals.

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