Spatially resolved surface topography retrieved from far-field intensity scattering measurements

2014 ◽  
Vol 53 (4) ◽  
pp. A297 ◽  
Author(s):  
Myriam Zerrad ◽  
Michel Lequime ◽  
Claude Amra
Keyword(s):  
Surface Topography ◽  
Field Intensity ◽  
Far Field ◽  
Spatially Resolved ◽  
Scattering Measurements

Surface roughness and substrate induced symmetry-breaking: influence on the plasmonic properties of aluminum nanostructure arrays

Nanoscale ◽  
2020 ◽  
Author(s):  
Feifei ZHANG ◽  
Jérôme Plain ◽  
Davy Gerard ◽  
Jérôme Martin
Keyword(s):  
Surface Roughness ◽  
Optical Properties ◽  
Symmetry Breaking ◽  
Surface Topography ◽  
Metallic Nanoparticles ◽  
Far Field ◽  
Al Nanoparticles ◽  
Nanostructure Arrays

The surface topography is known to play an important role on the near- and far- field optical properties of metallic nanoparticles. In particular, aluminum (Al) nanoparticles are commonly fabricated through...

Small-phase retrieval using single focused far-field intensity

Optik ◽  
2020 ◽  
Vol 218 ◽  
pp. 164904
Author(s):  
Qian Ye ◽  
Dafei Xiao
Keyword(s):  
Field Intensity ◽  
Phase Retrieval ◽  
Far Field ◽  
Small Phase

scholarly journals Variations in Cell Surfaces of Estrogen Treated Breast Cancer Cells Detected by A Combined Instrument for Far-Field and Near-Field Microscopy

2002 ◽  
Vol 24 (2-3) ◽  
pp. 89-100 ◽  
Author(s):  
P. Perner ◽  
A. Rapp ◽  
C. Dressler ◽  
L. Wollweber ◽  
J. Beuthan ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Cells ◽  
Surface Topography ◽  
Breast Cancer Cells ◽  
Light Transmission ◽  
Single Cells ◽  
Near Field ◽  
Far Field ◽  
Breast Cancers ◽  
General Behaviour

The response of single breast cancer cells (cell line T‐47D) to 17β‐estradiol (E2) under different concentrations was studied by using an instrument that allows to combine far‐field light microscopy with high resolution scanning near‐field (AFM/SNOM) microscopy on the same cell. Different concentrations of E2induce clearly different effects as well on cellular shape (in classical bright‐field imaging) as on surface topography (atomic force imaging) and absorbance (near‐field light transmission imaging). The differences range from a polygonal shape at zero via a roughly spherical shape at physiological up to a spindle‐like shape at un‐physiologically high concentrations. The surface topography of untreated control cells was found to be regular and smooth with small overall height modulations. At physiological E2concentrations the surfaces became increasingly jagged as detected by an increase in membrane height. After application of the un‐physiological high E2concentration the cell surface structures appeared to be smoother again with an irregular fine structure. The general behaviour of dose dependent differences was also found in the near‐field light transmission images. In order to quantify the treatment effects, line scans through the normalised topography images were drawn and a rate of co‐localisation between high topography and high transmission areas was calculated. The cell biological aspects of these observations are, so far, not studied in detail but measurements on single cells offer new perspectives to be empirically used in diagnosis and therapy control of breast cancers.

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