scholarly journals Super-resolution: 3-D Imaging, Multiparticle Parallel Tracking, and Time-resolved Imaging

2017 ◽  
Author(s):  
Junle Qu
Keyword(s):  
Super Resolution ◽  
Time Resolved ◽  
Time Resolved Imaging

scholarly journals Giant enhancement of THz-frequency optical nonlinearity by phonon polariton in ionic crystals

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Yao Lu ◽  
Qi Zhang ◽  
Qiang Wu ◽  
Zhigang Chen ◽  
Xueming Liu ◽  
...  
Keyword(s):  
Near Infrared ◽  
Optical Nonlinearity ◽  
Ionic Crystals ◽  
Nonlinear Optical Susceptibility ◽  
Time Resolved ◽  
Light Coupling ◽  
Tremendous Progress ◽  
Fundamental Research ◽  
Ionic Contribution ◽  
Time Resolved Imaging

AbstractThe field of nonlinear optics has grown substantially in past decades, leading to tremendous progress in fundamental research and revolutionized applications. Traditionally, the optical nonlinearity for a light wave at frequencies beyond near-infrared is observed with very high peak intensity, as in most materials only the electronic nonlinearity dominates while ionic contribution is negligible. However, it was shown that the ionic contribution to nonlinearity can be much larger than the electronic one in microwave experiments. In the terahertz (THz) regime, phonon polariton may assist to substantially trigger the ionic nonlinearity of the crystals, so as to enhance even more the nonlinear optical susceptibility. Here, we experimentally demonstrate a giant second-order optical nonlinearity at THz frequency, orders of magnitude higher than that in the visible and microwave regimes. Different from previous work, the phonon-light coupling is achieved under a phase-matching setting, and the dynamic process of nonlinear THz generation is directly observed in a thin-film waveguide using a time-resolved imaging technique. Furthermore, a nonlinear modification to the Huang equations is proposed to explain the observed nonlinearity enhancement. This work brings about an effective approach to achieve high nonlinearity in ionic crystals, promising for applications in THz nonlinear technologies.

scholarly journals Super-resolution time-resolved imaging using computational sensor fusion

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
C. Callenberg ◽  
A. Lyons ◽  
D. den Brok ◽  
A. Fatima ◽  
A. Turpin ◽  
...  
Keyword(s):  
Sensor Fusion ◽  
Spatial Resolution ◽  
Temporal Resolution ◽  
Single Photon ◽  
Super Resolution ◽  
Numerical Data ◽  
Data Cube ◽  
Fluorescence Lifetime Imaging ◽  
Time Resolved ◽  
Temporal Precision

AbstractImaging across both the full transverse spatial and temporal dimensions of a scene with high precision in all three coordinates is key to applications ranging from LIDAR to fluorescence lifetime imaging. However, compromises that sacrifice, for example, spatial resolution at the expense of temporal resolution are often required, in particular when the full 3-dimensional data cube is required in short acquisition times. We introduce a sensor fusion approach that combines data having low-spatial resolution but high temporal precision gathered with a single-photon-avalanche-diode (SPAD) array with data that has high spatial but no temporal resolution, such as that acquired with a standard CMOS camera. Our method, based on blurring the image on the SPAD array and computational sensor fusion, reconstructs time-resolved images at significantly higher spatial resolution than the SPAD input, upsampling numerical data by a factor $$12 \times 12$$ 12 × 12 , and demonstrating up to $$4 \times 4$$ 4 × 4 upsampling of experimental data. We demonstrate the technique for both LIDAR applications and FLIM of fluorescent cancer cells. This technique paves the way to high spatial resolution SPAD imaging or, equivalently, FLIM imaging with conventional microscopes at frame rates accelerated by more than an order of magnitude.

scholarly journals Time-resolved imaging refractometry of microbicidal films using quantitative phase microscopy

2011 ◽  
Vol 16 (12) ◽  
pp. 120510 ◽  
Author(s):  
Matthew T. Rinehart ◽  
Tyler K. Drake ◽  
Francisco E. Robles ◽  
Lisa C. Rohan ◽  
David Katz ◽  
...  
Keyword(s):  
Time Resolved ◽  
Quantitative Phase ◽  
Phase Microscopy ◽  
Quantitative Phase Microscopy ◽  
Time Resolved Imaging

scholarly journals Time-Resolved Imaging of Electrochemical Switching in Nanoscale Resistive Memory Elements

2015 ◽  
Vol 21 (S3) ◽  
pp. 1911-1912
Author(s):  
William A. Hubbard ◽  
E. R. White ◽  
Alexander Kerelsky ◽  
G. Jasmin ◽  
Jared J. Lodico ◽  
...  
Keyword(s):  
Resistive Memory ◽  
Time Resolved ◽  
Time Resolved Imaging

scholarly journals Two-Photon Time-Gated In Vivo Imaging of Dihydrolipoic-Acid-Decorated Gold Nanoclusters

Materials ◽  
2021 ◽  
Vol 14 (24) ◽  
pp. 7744
Author(s):  
Ye Tian ◽  
Ming Wei ◽  
Lijun Wang ◽  
Yuankai Hong ◽  
Dan Luo ◽  
...  
Keyword(s):  
In Vivo Imaging ◽  
Gold Nanoclusters ◽  
Photon Absorption ◽  
Gold Nanocluster ◽  
Time Resolved ◽  
Dihydrolipoic Acid ◽  
Two Photon Absorption ◽  
Two Photon ◽  
Time Resolved Imaging

Due to the unique advantages of two-photon technology and time-resolved imaging technology in the biomedical field, attention has been paid to them. Gold clusters possess excellent physicochemical properties and low biotoxicity, which make them greatly advantageous in biological imaging, especially for in vivo animal imaging. A gold nanocluster was coupled with dihydrolipoic acid to obtain a functionalized nanoprobe; the material displayed significant features, including a large two-photon absorption cross-section (up to 1.59 × 105 GM) and prolonged fluorescence lifetime (>300 ns). The two-photon and time-resolution techniques were used to perform cell imaging and in vivo imaging.

scholarly journals The C-terminal helix 9 motif in rat cannabinoid receptor type 1 regulates axonal trafficking and surface expression

eLife ◽  
2019 ◽  
Vol 8 ◽  
Author(s):  
Alexandra Fletcher-Jones ◽  
Keri L Hildick ◽  
Ashley J Evans ◽  
Yasuko Nakamura ◽  
Kevin A Wilkinson ◽  
...  
Keyword(s):  
Hippocampal Neurons ◽  
Secretory Pathway ◽  
Cannabinoid Receptor ◽  
Surface Expression ◽  
Surface Polarity ◽  
Time Resolved ◽  
Surface Stability ◽  
C Terminus ◽  
Time Resolved Imaging ◽  
Dual Mechanism

Cannabinoid type one receptor (CB1R) is only stably surface expressed in axons, where it downregulates neurotransmitter release. How this tightly regulated axonal surface polarity is established and maintained is unclear. To address this question, we used time-resolved imaging to determine the trafficking of CB1R from biosynthesis to mature polarised localisation in cultured rat hippocampal neurons. We show that the secretory pathway delivery of CB1R is axonally biased and that surface expressed CB1R is more stable in axons than in dendrites. This dual mechanism is mediated by the CB1R C-terminus and involves the Helix 9 (H9) domain. Removal of the H9 domain increases secretory pathway delivery to dendrites and decreases surface stability. Furthermore, CB1RΔH9 is more sensitive to agonist-induced internalisation and less efficient at downstream signalling than CB1RWT. Together, these results shed new light on how polarity of CB1R is mediated and indicate that the C-terminal H9 domain plays key roles in this process.

Time-Resolved Imaging Study of Jetting Dynamics during Laser Printing of Viscoelastic Alginate Solutions

Langmuir ◽  
2015 ◽  
Vol 31 (23) ◽  
pp. 6447-6456 ◽  
Author(s):  
Zhengyi Zhang ◽  
Ruitong Xiong ◽  
Renwei Mei ◽  
Yong Huang ◽  
Douglas B. Chrisey
Keyword(s):  
Imaging Study ◽  
Time Resolved ◽  
Laser Printing ◽  
Time Resolved Imaging
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