Investigation on the effect of peptides mixture from tumor cells inducing anti-tumor specific immune response

2002 ◽  
Vol 45 (4) ◽  
pp. 361 ◽  
Author(s):  
Zuohua FENG
Keyword(s):  
Immune Response ◽  
Tumor Cells ◽  
Specific Immune Response ◽  
Tumor Specific Immune Response

Human Tumor Cells Killed by Anthracyclines Induce a Tumor-Specific Immune Response

2011 ◽  
Vol 71 (14) ◽  
pp. 4821-4833 ◽  
Author(s):  
Jitka Fucikova ◽  
Petra Kralikova ◽  
Anna Fialova ◽  
Tomas Brtnicky ◽  
Lukas Rob ◽  
...  
Keyword(s):  
Immune Response ◽  
Tumor Cells ◽  
Human Tumor ◽  
Specific Immune Response ◽  
Human Tumor Cells ◽  
Tumor Specific Immune Response

Analysis of mixed lymphocyte-tumor culture in patients with malignant brain tumor

1989 ◽  
Vol 71 (3) ◽  
pp. 398-402 ◽  
Author(s):  
Seiichi Yoshida ◽  
Ryuichi Tanaka ◽  
Masashi Ono ◽  
Nobuyuki Takai ◽  
Takafumi Saito
Keyword(s):  
Immune Response ◽  
Brain Tumor ◽  
Brain Tumors ◽  
Tumor Cells ◽  
Tumor Infiltrating Lymphocytes ◽  
Peripheral Blood Lymphocytes ◽  
Malignant Brain Tumor ◽  
Specific Immune Response ◽  
Content Type ◽  
Tumor Specific Immune Response

✓ To ascertain whether tumor-specific immune response occurs in patients with malignant brain tumors, lymphocyte blastogenetic responses to tumor cells were examined in 18 patients prior to operation and other treatment. Among 12 patients with malignant glioma, the peripheral blood lymphocytes (PBL's) showed a positive blastogenetic response to their own glioma cells in seven (58.3%), whereas the tumor-infiltrating lymphocytes (TIL's) showed a positive response in only three (25%). In four (66.7%) of six patients with metastatic brain tumors, however, both the PBL's and TIL's showed a positive blastogenetic response to their own tumor cells. In these four patients, this lymphocyte blastogenetic response to tumor cells were at a much lower level compared with phytohemagglutinin P or allogeneic lymphocyte stimulation. Furthermore, these responses were increased when the cells were cultured with interferon-γ (500 U). Other lymphokines had no effect on the response. This method appears to be useful in identifying the tumor-specific immune response in patients with malignant brain tumor.

scholarly journals The tumor specific immune response of experimental active-specific immunotherapy

Cancer ◽  
1977 ◽  
Vol 39 (2) ◽  
pp. 565-569
Author(s):  
Anthony A. Meyer ◽  
Warren E. Enker ◽  
Janet L. Jacobitz ◽  
Robert W. Wissler ◽  
Karen Craft
Keyword(s):  
Immune Response ◽  
Specific Immunotherapy ◽  
Specific Immune Response ◽  
Active Specific Immunotherapy ◽  
Tumor Specific Immune Response

scholarly journals Exosomes Isolated from Ascites of T-Cell Lymphoma-Bearing Mice Expressing Surface CD24 and HSP-90 Induce a Tumor-Specific Immune Response

2017 ◽  
Vol 8 ◽  
Author(s):  
Florencia Menay ◽  
Leticia Herschlik ◽  
Julieta De Toro ◽  
Federico Cocozza ◽  
Rodrigo Tsacalian ◽  
...  
Keyword(s):  
Immune Response ◽  
T Cell ◽  
Cell Lymphoma ◽  
T Cell Lymphoma ◽  
Specific Immune Response ◽  
Hsp 90 ◽  
Tumor Specific Immune Response

scholarly journals ANTIGENIC SPECIFICITIES ON MURINE SARCOMA CELLS

1971 ◽  
Vol 133 (6) ◽  
pp. 1171-1187 ◽  
Author(s):  
Gerald R. Haywood ◽  
Charles F. McKhann
Keyword(s):  
Immune Response ◽  
Inverse Relationship ◽  
Specific Immune Response ◽  
Antigenic Specificity ◽  
Surface Representation ◽  
Low Levels ◽  
Sarcoma Cells ◽  
Individual Specificity ◽  
Murine Sarcoma ◽  
Tumor Specific Immune Response

Five methylcholanthrene-induced sarcomas were compared for their capacity to (a) absorb monospecific H-2 antisera, (b) induce tumor-specific immunity in syngeneic mice, and (c) metastasize early to the lungs. Comparison of the uptakes of monospecific H-2 antisera by the five different tumors showed that each of the tumors had a high, intermediate, or low surface representation of all of the seven specificities tested. No antigenic specificity was completely absent from any tumor, and no tumor had an unusually large or small amount of any individual specificity. The tumors could be placed in the sequence from one to five with respect to their H-2 antigenicity. The same five tumors were also ranked with respect to their capacity to induce a tumor-specific immune response in syngeneic mice. The tumor-specific immunogenicity had an inverse relationship to the H-2 antigenicity in that highly immunogenic tumors were those that had quantitatively less H-2 antigen on their surface and vice versa. Early metastases to the lung was associated with low levels of tumor-specific immunogenicity and high levels of H-2 antigenicity.

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