Demographics of Meningitis-Induced Hearing Impairment: Implications for Immunization of Children Against Hemophilus Influenzae Type B

1987 ◽  
Vol 132 (1) ◽  
pp. 26-30 ◽  
Author(s):  
Anthony B. Wolff ◽  
Scott Campbell Brown
Keyword(s):  
Hearing Impairment ◽  
Type B ◽  
Hemophilus Influenzae ◽  
Hemophilus Influenzae Type B

RESPONSES OF CHILDREN IMMUNIZED WITH THE CAPSULAR POLYSACCHARIDE OF HEMOPHILUS INFLUENZAE, TYPE b

PEDIATRICS ◽  
1973 ◽  
Vol 52 (5) ◽  
pp. 637-644
Author(s):  
David H. Smith ◽  
Georges Peter ◽  
David L. Ingram ◽  
A. Lynn Harding ◽  
Porter Anderson
Keyword(s):  
Capsular Polysaccharide ◽  
Geometric Mean ◽  
Antibody Concentration ◽  
Antibody Activity ◽  
Antigen Binding ◽  
Type B ◽  
Intramuscular Dose ◽  
Hemophilus Influenzae ◽  
Age Dependent ◽  
Hemophilus Influenzae Type B

One hundred forty-one children of 5 to 59 months of age were immunized with a single intramuscular dose of 0.67, 3.3, 17, or 67µg polyribophosphate (PRP), the capsular antigen of Hemophilus influenzae, type b. The immunizations were well tolerated, particularly at doses of .67 to 17µg. Antibody activity was measured by radioactive antigen binding, using 3H-labelled PRP. Doses of 3.3 and 17µg produced significant antibody rises in nearly 90% of recipients; 0.67 and 67µg in approximately half. The geometric mean titers were similar at three and six weeks after immunization and were greater with the middle doses. The net antibody increase in responding children was strongly age dependent, but was not related to the preimmunization antibody concentration. Rises in serum bactericidal activity against H. influenzae type b generally accompanied rises in antibody concentration as measured by the antigen-binding assay.

Prevention of Hemophilus influenzae type b disease

JAMA ◽  
1984 ◽  
Vol 251 (18) ◽  
pp. 2381-2386 ◽  
Author(s):  
J. D. Band
Keyword(s):  
Type B ◽  
Hemophilus Influenzae ◽  
Hemophilus Influenzae Type B

Prophylaxis of Hemophilus influenzae type b disease

JAMA ◽  
1984 ◽  
Vol 252 (23) ◽  
pp. 3249b-3250 ◽  
Author(s):  
J. D. Band
Keyword(s):  
Type B ◽  
Hemophilus Influenzae ◽  
Hemophilus Influenzae Type B

Bacteremic Epididymo-Orchitis Due to Hemophilus Influenzae Type B

1981 ◽  
Vol 126 (6) ◽  
pp. 832-833 ◽  
Author(s):  
Dolly Thomas ◽  
Kenneth Simpson ◽  
Hilde Ostojic ◽  
Aditya Kaul
Keyword(s):  
Type B ◽  
Hemophilus Influenzae ◽  
Hemophilus Influenzae Type B
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