scholarly journals Endocrine disruption in wildlife: The future?

2003 ◽  
Vol 75 (11-12) ◽  
pp. 2355-2360 ◽  
Author(s):  
J. P. Sumpter
Keyword(s):  
Endocrine Disruption ◽  
Sewage Treatment ◽  
Population Level ◽  
Paper Mill ◽  
Individual Organism ◽  
Paper Mill Effluent ◽  
The Future ◽  
Over Exploitation ◽  
The Individual ◽  
The Impact

Probably the only thing that can be said with certainty about the future of this field of ecotoxicology is that predicting it is foolish; the chances of being right are very slim. Instead, it seems to me likely that unexpected discoveries will probably have more influence on the field of endocrine disruption than the outcomes of all the planned experiments. It is certainly true that chance discoveries, such as masculinized fish in rivers receiving paper-mill effluent, imposex in molluscs due to exposure to tributyltin and feminized fish in rivers receiving effluent from sewage-treatment works, have been pivotal in the development of the field of endocrine disruption in wildlife. I consider that further such discoveries are likely, but I do not know which species will be affected, what effects will be found, what chemical(s) will be the cause, or what endocrine mechanism(s) will underlie the effects. The recent realization that many pharmaceuticals are present in the aquatic environment only underscores the range of effects that could, in theory at least, occur in exposed wildlife. What is somewhat easier to predict is the research that will be conducted in the immediate future, which will build upon what is known already. For example, it is clear that wildlife is rarely, if ever, exposed to single chemicals, but instead is exposed to highly complex, ill-defined mixtures of chemicals, including many that are endocrine active in various ways. We need to understand much better how chemicals interact, and what overall effects will occur upon exposure to such mixtures. We also need to move from assessing effects at the individual organism level, to understanding the consequences of these effects at the population level. Then, we need to determine the significance of any population-level effects due to endocrine disruption in comparison with the impact of many other significant stressors (e.g., over-exploitation, habitat loss, climate change) that also negatively impact wildlife. Such research will be difficult, and time-consuming, and will probably produce many surprises. All I can be fairly certain about is that the next few years are likely to be as interesting and exciting as the last few have been.

scholarly journals The impact of forms of unemployment on the social conditions in the Palestinian society from the point of view of the Palestinian youth in the current period between 2015 – 2019: تأثير أشكال البطالة على الأوضاع الاجتماعية في المجتمع الفلسطيني من وجهة نظر الشباب الفلسطيني في الفترة الزمنية الحالية ما بين 2015 – 2019م

2019 ◽  
Vol 3 (12) ◽  
Author(s):  
Abdelmajid Nayif Alawneh
Keyword(s):  
Low Income ◽  
Point Of View ◽  
Social Conditions ◽  
The Social ◽  
The Family ◽  
Palestinian Society ◽  
Individual Family ◽  
The Future ◽  
The Individual ◽  
The Impact

    The research aims to study the impact of unemployment on the social conditions in the Palestinian society from the point of view of the unemployed youth, especially in the current time period (2019), the researcher used the descriptive analytical method, and the research community consists of young people in the governorate of Ramallah. The researcher used the questionnaire tool, and the data were analyzed by the analysis program (SPSS). It was found that the majority of youth are unemployed, they are middle age, single and large families, urban residents, people with specialties and low income. As for the results of the research, there was an increase in the impact of the forms of unemployment on the social conditions of the individual, family and society and their outlook towards the future, came the highest degree on the social conditions of the individual (6. 90%) and then the social conditions of the family (3. 83%), Followed by the societal conditions to reach the value (78%), came the lowest values ​​for the outlook for the future, which amounted to (67%). Some of the features of the impact of unemployment, including the tension, anxiety and frustration of the young group. As for the nature of the relationship between the variables of the study, there was a statistically significant relationship between the combined unemployment and the low income, between the apparent, persuasive and compulsory unemployment, and the individual, family and societal situations and the outlook for them. At the end of the research a number of recommendations were made, most notably the need to balance the types of education and activate the social and cultural role of the family.  

scholarly journals Projecting Climate Change Impacts on Mediterranean Finfish Production: A Case Study in Greece.

2021 ◽  
Author(s):  
Orestis Stavrakidis-Zachou ◽  
Konstadia Lika ◽  
Panagiotis Anastasiadis ◽  
Nikos Papandroulakis
Keyword(s):  
Climate Change ◽  
Climate Change Impacts ◽  
Population Level ◽  
Extreme Weather ◽  
Extreme Weather Events ◽  
Mediterranean Country ◽  
Farm Level ◽  
Weather Events ◽  
The Future ◽  
The Individual

Abstract Finfish aquaculture in the Mediterranean Sea faces increasing challenges due to climate change while potential adaptation requires a robust assessment of the arising threats and opportunities. This paper presents an approach developed to investigate effects of climate drivers on Greek aquaculture, a representative Mediterranean country with a leading role in the sector. Using a farm level approach, Dynamic Energy Budget models for European seabass and meagre were developed and environmental forcing was used to simulate changes in production and farm profitability under IPCC scenarios RCP45 and RCP85. The effects of temperature and extreme weather events at the individual and farm level were considered along with that of husbandry parameters such as stocking timing, market size, and farm location (inshore, offshore) for nine regions. The simulations suggest that at the individual level fish may benefit from warmer temperatures in the future in terms of growth, thus reaching commercial sizes faster, while the husbandry parameters may have as large an effect on growth as the projected shifts in climatic cues. However, this benefit will be largely offset by the adverse effects of extreme weather events at the population level. Such events will be more frequent in the future and, depending on the intensity one assigns to them, they could cause losses in biomass and farm profits that range from mild to detrimental for the industry. Overall, these results provide quantification of some of the potential threats for an important aquaculture sector while suggesting possibilities to benefit from emerging opportunities. Therefore, they could contribute to improving the sector’s readiness for tackling important challenges in the future.

scholarly journals Analyzing 24-Hour Blood Pressure Measurements with a Novel Cuffless Pulse Transit Time Device in Clinical Practice—Does the Software for Heartbeat Detection Matter?

Diagnostics ◽  
2020 ◽  
Vol 10 (6) ◽  
pp. 361
Author(s):  
Leo Kilian ◽  
Philipp Krisai ◽  
Thenral Socrates ◽  
Christian Arranto ◽  
Otmar Pfister ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Transit Time ◽  
Pulse Transit Time ◽  
Population Level ◽  
Raw Data ◽  
Invasive Blood Pressure ◽  
Individual Level ◽  
Non Invasive ◽  
The Individual ◽  
The Impact

Background: The Somnotouch-Non-Invasive-Blood-Pressure (NIBP) device delivers raw data consisting of electrocardiography and photoplethysmography for estimating blood pressure (BP) over 24 h using pulse-transit-time. The study’s aim was to analyze the impact on 24-hour BP results when processing raw data by two different software solutions delivered with the device. Methods: We used data from 234 participants. The Somnotouch-NIBP measurements were analyzed using the Domino-light and Schiller software and compared. BP values differing >5 mmHg were regarded as relevant and explored for their impact on BP classification (normotension vs. hypertension). Results: Mean (±standard deviation) absolute systolic/diastolic differences for 24-hour mean BP were 1.5 (±1.7)/1.1 (±1.3) mm Hg. Besides awake systolic BP (p = 0.022), there were no statistically significant differences in systolic/diastolic 24-hour mean, awake, and asleep BP. Twenty four-hour mean BP agreement (number (%)) between the software solutions within 5, 10, and 15 mmHg were 222 (94.8%), 231 (98.7%), 234 (100%) for systolic and 228 (97.4%), 232 (99.1%), 233 (99.5%) for diastolic measurements, respectively. A BP difference of >5 mmHg was present in 24 (10.3%) participants leading to discordant classification in 4–17%. Conclusion: By comparing the two software solutions, differences in BP are negligible at the population level. However, at the individual level there are, in a minority of cases, differences that lead to different BP classifications, which can influence the therapeutic decision.

scholarly journals A big data analysis of the relationship between future thinking and decision-making

2018 ◽  
Vol 115 (8) ◽  
pp. E1740-E1748 ◽  
Author(s):  
Robert Thorstad ◽  
Phillip Wolff
Keyword(s):  
Decision Making ◽  
Big Data ◽  
Population Level ◽  
Future Thinking ◽  
Individual Level ◽  
The Future ◽  
The Individual ◽  
Near Future ◽  
The Relationship ◽  
Far Future

We use big data methods to investigate how decision-making might depend on future sightedness (that is, on how far into the future people’s thoughts about the future extend). In study 1, we establish a link between future thinking and decision-making at the population level in showing that US states with citizens having relatively far future sightedness, as reflected in their tweets, take fewer risks than citizens in states having relatively near future sightedness. In study 2, we analyze people’s tweets to confirm a connection between future sightedness and decision-making at the individual level in showing that people with long future sightedness are more likely to choose larger future rewards over smaller immediate rewards. In study 3, we show that risk taking decreases with increases in future sightedness as reflected in people’s tweets. The ability of future sightedness to predict decisions suggests that future sightedness is a relatively stable cognitive characteristic. This implication was supported in an analysis of tweets by over 38,000 people that showed that future sightedness has both state and trait characteristics (study 4). In study 5, we provide evidence for a potential mechanism by which future sightedness can affect decisions in showing that far future sightedness can make the future seem more connected to the present, as reflected in how people refer to the present, past, and future in their tweets over the course of several minutes. Our studies show how big data methods can be applied to naturalistic data to reveal underlying psychological properties and processes.

scholarly journals IMAGE OF THE FUTURE: DESIGN AND REPRESENTATION

2020 ◽  
pp. 84-95
Author(s):  
M. K. Kremenchutska ◽  
І. V. Dobrynina
Keyword(s):  
Mental Representations ◽  
Holistic View ◽  
Future Design ◽  
The World ◽  
The Future ◽  
The Individual ◽  
The Mind ◽  
Images Of The Future ◽  
The Impact ◽  
World Image

Problem statement. It is shown that the main scientific vectors of the study of the personality image of the future can be considered philosophical, sociological, psychophysiological and psychological. In psychology, the future is revealed as a property of the mental. It is determined that the psychological phenomenology of the image of the future is that it is a holistic view of the individual about the future. It is in the mind and constantly affects behavior, activities, and its emotional state. The ability of an individual to construct his own future is due to the peculiarities of his individual psychological representations. This aspect is little studied in psychological science.  The purpose of the article is to present methods and techniques of research of representations and designing the world image of the future by the person. Results of the research. It is noted that the process of forming the image of the future is not only a vision of the end result, but also the impact on the assessment of behavior, consolidation of moral, volitional, intellectual efforts to realize their own expectations. This emphasizes the subjective nature of this process. In the framework of the research of mental representations and the peculiarities of constructing personality images of the future in a particular individual context were identified the mediative and moderative components that influence this phenomenon. The author’s method of assessing the world image of the future is presented. It is a technique of subjective scaling — that is, it shows how the individual imagines his future. To assess the relationship between the studied indicators, which are operationalized as concepts of psychosemantic analysis, a multidimensional deployment was used. Conclusions and prospects for further research. It is concluded that the psychosemantic approach is the most informative in the identified abilities of the individual to construct images of their own future. It is noted that the prospects for further research will be to identify the re lationship between forms and strategies for building mental representations of the image of the future with strategies for individual behavior in difficult life situations.

scholarly journals The Normative Underpinnings of Population-Level Alcohol Use: An Individual-Level Simulation Model

2020 ◽  
Vol 47 (2) ◽  
pp. 224-234
Author(s):  
Charlotte Probst ◽  
Tuong Manh Vu ◽  
Joshua M. Epstein ◽  
Alexandra E. Nielsen ◽  
Charlotte Buckley ◽  
...  
Keyword(s):  
Alcohol Use ◽  
Social Norms ◽  
Drinking Behavior ◽  
Population Level ◽  
Drinking Patterns ◽  
Individual Level ◽  
Behavioral Rules ◽  
Level Model ◽  
The Individual ◽  
The Impact

Background. By defining what is “normal,” appropriate, expected, and unacceptable, social norms shape human behavior. However, the individual-level mechanisms through which social norms impact population-level trends in health-relevant behaviors are not well understood. Aims. To test the ability of social norms mechanisms to predict changes in population-level drinking patterns. Method. An individual-level model was developed to simulate dynamic normative mechanisms and behavioral rules underlying drinking behavior over time. The model encompassed descriptive and injunctive drinking norms and their impact on frequency and quantity of alcohol use. A microsynthesis initialized in 1979 was used as a demographically representative synthetic U.S. population. Three experiments were performed in order to test the modelled normative mechanisms. Results. Overall, the experiments showed limited influence of normative interventions on population-level alcohol use. An increase in the desire to drink led to the most meaningful changes in the population’s drinking behavior. The findings of the experiments underline the importance of autonomy, that is, the degree to which an individual is susceptible to normative influence. Conclusion. The model was able to predict theoretically plausible changes in drinking patterns at the population level through the impact of social mechanisms. Future applications of the model could be used to plan norms interventions pertaining to alcohol use as well as other health behaviors.

scholarly journals African Gene Flow Reduces Beta-Ionone Anosmia/Hyposmia Prevalence in Admixed Malagasy Populations

2021 ◽  
Vol 11 (11) ◽  
pp. 1405
Author(s):  
Harilanto Razafindrazaka ◽  
Veronica Pereda-Loth ◽  
Camille Ferdenzi ◽  
Margit Heiske ◽  
Omar Alva ◽  
...  
Keyword(s):  
Gene Flow ◽  
African Ancestry ◽  
Sensory Perception ◽  
Population Level ◽  
P Value ◽  
Individual Level ◽  
Specific Anosmia ◽  
Odorant Molecule ◽  
The Individual ◽  
The Impact

While recent advances in genetics make it possible to follow the genetic exchanges between populations and their phenotypic consequences, the impact of the genetic exchanges on the sensory perception of populations has yet to be explored. From this perspective, the present study investigated the consequences of African gene flow on odor perception in a Malagasy population with a predominantly East Asian genetic background. To this end, we combined psychophysical tests with genotype data of 235 individuals who were asked to smell the odorant molecule beta-ionone (βI). Results showed that in this population the ancestry of the OR5A1 gene significantly influences the ability to detect βI. At the individual level, African ancestry significantly protects against specific anosmia/hyposmia due to the higher frequency of the functional gene (OR ratios = 14, CI: 1.8–110, p-value = 0.012). At the population level, African introgression decreased the prevalence of specific anosmia/hyposmia to this odorous compound. Taken together, these findings validate the conjecture that in addition to cultural exchanges, genetic transfer may also influence the sensory perception of the population in contact.

Russian Religious Philosopher K.N. Leontiev: Personality Transformation in the Space of the Orthodox Culture of Athos

2017 ◽  
Vol 6 (3) ◽  
pp. 32-37
Author(s):  
С. Дивногорцева ◽  
S. Divnogorceva
Keyword(s):  
Early Childhood ◽  
Spiritual Transformation ◽  
Russian Society ◽  
Special Role ◽  
Monastic Life ◽  
The Future ◽  
Russian Intelligentsia ◽  
The Individual ◽  
The Impact

Athos has always played a special role in the life of Russian society. She was always an example of the proper organization of monastic life for many Russian ascetics. Important trail she left in the life of the Russian intelligentsia. Its dispensation has transformed their attitude towards life and aspirations. This article describes the part of the life of the Russian religious philosopher K.N. Leontiev in the context of the impact space of the Orthodox culture of Athos. The author considers the question of spiritual transformation of the personality of the philosopher, examines the origins of several of his works, religious and philosophical views. The author pays special attention to the formation of the individual of K.N.Leontiev in early childhood and traces the impact of this in the future writer's biography. The author dwells in detail on the characteristics of the personality of the philosopher, as he believes that it is inseparable from his books.

scholarly journals A multi-scale epidemic model of Salmonella infection with heterogeneous shedding

2020 ◽  
Vol 67 ◽  
pp. 261-284
Author(s):  
Simon Labarthe ◽  
Béatrice Laroche ◽  
Thi Nhu Tao Nguyen ◽  
Bastien Polizzi ◽  
Florian Patout ◽  
...  
Keyword(s):  
Control Strategies ◽  
Food Poisoning ◽  
Population Level ◽  
Pathogen Transmission ◽  
Modeling Framework ◽  
Multi Scale ◽  
Multiscale Modeling Framework ◽  
The Individual ◽  
Random Fluctuations ◽  
The Impact

Salmonella strains colonize the digestive tract of farm livestock, such as chickens or pigs, without affecting them, and potentially infect food products, representing a threat for human health ranging from food poisoning to typhoid fever. It has been shown that the ability to excrete the pathogen in the environment and contaminate other animals is variable. This heterogeneity in pathogen carriage and shedding results from interactions between the host’s immune response, the pathogen and the commensal intestinal microbiota. In this paper we propose a novel generic multiscale modeling framework of heterogeneous pathogen transmission in an animal population. At the intra-host level, the model describes the interaction between the commensal microbiota, the pathogen and the inflammatory response. Random fluctuations in the ecological dynamics of the individual microbiota and transmission at between-host scale are added to obtain a drift-diffusion PDE model of the pathogen distribution at the population level. The model is further extended to represent transmission between several populations. The asymptotic behavior as well as the impact of control strategies including cleaning and antimicrobial administration are investigated through numerical simulation.

Endocrine disruption, parasites and pollutants in wild freshwater fish

Parasitology ◽  
2003 ◽  
Vol 126 (7) ◽  
pp. S103-S107 ◽  
Author(s):  
S. JOBLING ◽  
C. R. TYLER
Keyword(s):  
Freshwater Fish ◽  
Endocrine Disruption ◽  
Health Effect ◽  
Sewage Treatment ◽  
Environmental Pollutants ◽  
Gonad Development ◽  
Endocrine System ◽  
Population Level ◽  
Adverse Environmental Conditions ◽  
Treated Sewage Effluent

Disruption of the endocrine system has been shown to occur in wild freshwater fish populations across the globe. Effects range from subtle changes in the physiology and sexual behaviour of fish to permanently altered sexual differentiation, impairment of gonad development and/or altered fertility. A wide variety of adverse environmental conditions may induce endocrine disruption, including sub-optimal temperatures, restricted food supply, low pH, environmental pollutants, and/or parasites. Furthermore, it is conceivable that any/all of these factors could act simultaneously to cause a range of disparate or inter-related effects. Some of the strongest evidence for a link between an adverse health effect, as a consequence of endocrine disruption, and a causative agent(s) is between the condition of intersex in wild roach (Rutlius rutilus) in UK rivers and exposure to effluents from sewage treatment works. The evidence to indicate that intersex in roach (and other cyprinid fish living in these rivers) is caused by chemicals that mimic and/or disrupt hormone function/balance in treated sewage effluent is substantial. There are a few parasites that affect the endocrine system directly in fish, including the tape worm Ligula intestinalis and a few parasites from the micropsora phylum. L. intestinalis acts at the level of the hypothalamus restricting GnRH secretion (resulting in poorly developed gonads) and is one of the very few examples where an endocrine disrupting event has been shown to result in a population-level effect (reducing it). It is well established that many parasites affect the immune system and thus the most common effect of parasites on the endocrine system in fish is likely to be an indirect one.

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