A Qualitative Investigation of Long-Term Zopiclone Use and Sleep Quality Among Vietnam War Veterans with PTSD

2009 ◽  
Vol 43 (10) ◽  
pp. 1576-1582 ◽  
Author(s):  
Christopher P Alderman ◽  
Andrew L Gilbert
Keyword(s):  
Sleep Quality ◽  
Vietnam War ◽  
Qualitative Investigation ◽  
War Veterans ◽  
Vietnam War Veterans

scholarly journals Sleep and Tau Pathology in Vietnam War Veterans with Preclinical and Prodromal Alzheimer’s Disease

2020 ◽  
Author(s):  
Murray John Andrews ◽  
Ryan Ross ◽  
Atul Malhotra ◽  
Sonia Ancoli-Israel ◽  
James Brewer ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Sleep Quality ◽  
Vietnam War ◽  
Standardized Uptake Value ◽  
Post Traumatic Stress ◽  
War Veterans ◽  
Cross Sectional ◽  
Amyloid Pathology ◽  
Vietnam War Veterans

Abstract Background The increasing prevalence of Alzheimer’s Disease (AD) and lack of effective medications has led to a need to identify modifiable risk factors as targets for interventions. In this cross-sectional study, we sought to determine whether worse sleep quality is associated with increased pathological tau, and whether this relationship is affected by amyloid pathology. Methods 66 male participants underwent Florbetapir (AV45) Positron Emission Tomography (PET), Flortaucipir (FTP) PET and completed the Pittsburgh Sleep Quality Index questionnaire (PSQI) as part of the Department of Defense Alzheimer’s Disease Neuroimaging Initiative, a multicenter study collecting data from Vietnam War veterans, some of whom have a history of Post-Traumatic Stress Disorder (PTSD), or non-penetrating Traumatic Brain Injury (TBI). AV45 PET was used to determine the presence of significant amyloid pathology, and t-tests were used to assess differences in tau deposition in Braak regions associated with AD progression between amyloid positive and amyloid negative individuals. We used regression models to determine the effects of amyloid pathology and PSQI on tau deposition in Braak regions. Results Among the 66 participants, the average (SD) age was 71.04 (0.99) years. 14 individuals were amyloid positive (21%), and 52 were amyloid negative (79%). The amyloid positive and amyloid negative groups did not differ in tau in the regions investigated. There were no significant main effects of amyloid status or PSQI on FTP Standardized Uptake Value ratio (SUVr) in any of the regions investigated. However, in Braak stages III-IV, there was a significant interaction of amyloid status on PSQI (β = 0.039, p = 0.035) with higher PSQI correlating with higher FTP SUVr in amyloid-positive individuals only (β = 0.031, p = 0.017). Conclusions Our study found that an AD profile of tau deposition was associated with an interaction between self-reported sleep quality and amyloid pathology such that worse self-reported sleep was related to higher tau in regions associated with AD progression, but only in individuals with high cerebral amyloid deposition. Our study suggests that sleep quality may be a modifiable risk factor in preclinical and prodromal populations of AD.

scholarly journals Sleep and Tau Pathology in Vietnam War Veterans with Preclinical and Prodromal Alzheimer’s Disease

2021 ◽  
pp. 1-8
Author(s):  
Murray Andrews ◽  
Ryan Ross ◽  
Atul Malhotra ◽  
Sonia Ancoli-Israel ◽  
James Brewer ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Sleep Quality ◽  
Vietnam War ◽  
Brain Regions ◽  
Post Traumatic Stress ◽  
War Veterans ◽  
Cross Sectional ◽  
Amyloid Pathology ◽  
Vietnam War Veterans

Background: The increasing prevalence of Alzheimer’s disease (AD) and lack of effective medications has led to a need to identify modifiable risk factors as targets for interventions. Objective: In this cross-sectional study, we sought to determine whether worse sleep quality is associated with increased pathological tau, and whether this relationship is affected by amyloid pathology. Methods: 66 male participants underwent Florbetapir (AV45) positron emission tomography (PET) and Flortaucipir (FTP) PET and completed the Pittsburgh Sleep Quality Index questionnaire (PSQI) as part of the Department of Defense Alzheimer’s Disease Neuroimaging Initiative, a multicenter study collecting data from Vietnam War veterans, some of whom have a history of post-traumatic stress disorder, or non-penetrating traumatic brain injury. AV45 PET was used to determine the presence of significant amyloid pathology. We used regression models to determine the effects of amyloid pathology and PSQI on tau deposition in brain regions associated with Braak stages. Results: Among the 66 participants, 14 individuals were amyloid positive (21%) and 52 were amyloid negative (79%). In regions associated with Braak stages III-IV, there was a significant interaction of amyloid status on PSQI (β= 0.04, p = 0.003) with higher PSQI correlating with higher FTP SUVr in amyloid-positive individuals only (β= 0.031, p = 0.005). Conclusion: Our study found that an AD profile of tau deposition was associated with an interaction between self-reported sleep quality and amyloid pathology such that worse self-reported sleep was related to higher tau in regions usually associated with AD progression, but only in individuals with high cerebral amyloid deposition.

scholarly journals Classification of Mental Health among Korean Vietnam War Veterans: A Latent Profile Analysis

2020 ◽  
Vol 4 (Supplement_1) ◽  
pp. 637-637
Author(s):  
Hyunyup Lee ◽  
Carolyn Aldwin ◽  
Sungrok Kang ◽  
Xyle Ku
Keyword(s):  
Mental Health ◽  
Vietnam War ◽  
Military Service ◽  
Latent Profile Analysis ◽  
Service Providers ◽  
Profile Analysis ◽  
Well Being ◽  
War Veterans ◽  
Vietnam War Veterans ◽  
Latent Profile

Abstract We investigated the dimensional structure of mental health among aging Korean Veterans using latent profile analysis (LPA) on posttraumatic stress disorder symptoms (PTSD), late onset stress symptomology (LOSS), and psychosocial well-being (PWB). The Korean Vietnam War Veterans Study consists of 367 men (Mage=72, SD=2.66). LPA identified five classes of mental health as best fitting the data. Most men were in the normal (38%) and moderate distress (31%) groups, while smaller proportions were in the low affect (13%) and severe distress (7%) groups. The resilient group (12%) had low PTSD, medium LOSS, and high PWB, and were highest on optimism, positive appraisals of military service, and social support. Negative and positive aspects of mental health outcomes were on separate dimensions rather than on a single bipolar dimension. Service providers should attempt to both reduce Veterans’ negative psychological symptoms and increase psychosocial well-being. Part of a symposium sponsored by the Aging Veterans: Effects of Military Service across the Life Course Interest Group.

The Colonized Colonizers: Korean Experiences of the Vietnam War

1998 ◽  
Vol 7 (3-4) ◽  
pp. 217-240
Author(s):  
Jinim Park
Keyword(s):  
Vietnam War ◽  
Health Effects ◽  
Agent Orange ◽  
District Court ◽  
The South ◽  
War Veterans ◽  
South Korean ◽  
The Vietnam War ◽  
Vietnam War Veterans

AbstractOn 15 February 1997, the South Korean newspaper Chosun Ilbo reported that the Seoul District Court had rejected an appeal by the Korean Vietnam War veterans who had asked for compensation relating to the health effects of having been exposed to Agent Orange during their service in Vietnam.

Return to Vietnam

2021 ◽  
Author(s):  
Mia Martin Hobbs
Keyword(s):  
Oral History ◽  
Vietnam War ◽  
Sense Of Belonging ◽  
Historical Study ◽  
Viet Nam ◽  
War Veterans ◽  
War Memory ◽  
War Narratives ◽  
Vietnam War Veterans

Between 1981 and 2016, thousands of American and Australian Vietnam War veterans returned to Việt Nam. This comparative, transnational oral history offers the first historical study of these return journeys. It shows how veterans returned in search of resolution, or peace, manifesting in shifting nostalgic visions of 'Vietnam.' Different national war narratives shaped their returns: Australians followed the 'Anzac' pilgrimage tradition, whereas for Americans the return was an anti-war act. Veterans met former enemies, visited battlefields, mourned friends, found new relationships, and addressed enduring legacies of war. Many found their memories of war eased by witnessing Việt Nam at peace. Yet this peacetime reality also challenged veterans' wartime connection to Vietnamese spaces. The place they were nostalgic for was Vietnam, a space in war memory, not Việt Nam, the country. Veterans drew from wartime narratives to negotiate this displacement, performing nostalgic practices to reclaim their sense of belonging.

Sleep Diaries of Vietnam War Veterans With Chronic PTSD: The Relationships Among Insomnia Symptoms, Psychosocial Stress, and Nightmares

2014 ◽  
Vol 13 (3) ◽  
pp. 255-264 ◽  
Author(s):  
Philip R. Gehrman ◽  
Gerlinde C. Harb ◽  
Joan M. Cook ◽  
Holly Barilla ◽  
Richard J. Ross
Keyword(s):  
Vietnam War ◽  
Psychosocial Stress ◽  
War Veterans ◽  
Sleep Diaries ◽  
Chronic Ptsd ◽  
Vietnam War Veterans ◽  
Insomnia Symptoms

[IC-P-134]: TAU, Aβ-AMYLOID, AND COGNITIVE FUNCTION FOLLOWING SERVICE-RELATED TRAUMATIC BRAIN INJURY IN VIETNAM WAR VETERANS

2017 ◽  
Vol 13 (7S_Part_2) ◽  
pp. P101-P101
Author(s):  
Tia L. Cummins ◽  
Alby Elias ◽  
Mal Hopwood ◽  
Jeffrey V. Rosenfeld ◽  
Vincent Dore ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Cognitive Function ◽  
Vietnam War ◽  
War Veterans ◽  
Aβ Amyloid ◽  
Vietnam War Veterans

scholarly journals Agent Orange exposure, Vietnam War veterans, and the risk of prostate cancer

Cancer ◽  
2008 ◽  
Vol 113 (9) ◽  
pp. 2464-2470 ◽  
Author(s):  
Karim Chamie ◽  
Ralph W. deVere White ◽  
Dennis Lee ◽  
Joonha Ok ◽  
Lars M. Ellison
Keyword(s):  
Prostate Cancer ◽  
Vietnam War ◽  
Agent Orange ◽  
War Veterans ◽  
Vietnam War Veterans

Examining the role of combat loss among Vietnam War veterans

2012 ◽  
Vol 25 (1) ◽  
pp. 102-105 ◽  
Author(s):  
Joseph M. Currier ◽  
Jason M. Holland
Keyword(s):  
Vietnam War ◽  
War Veterans ◽  
Vietnam War Veterans

Serum dioxin levels and sperm DNA methylation age: Findings in Vietnam war veterans exposed to Agent Orange

2020 ◽  
Vol 96 ◽  
pp. 27-35
Author(s):  
Jamaji C. Nwanaji-Enwerem ◽  
Timothy G. Jenkins ◽  
Elena Colicino ◽  
Andres Cardenas ◽  
Andrea A. Baccarelli ◽  
...  
Keyword(s):  
Dna Methylation ◽  
Vietnam War ◽  
Agent Orange ◽  
War Veterans ◽  
Sperm Dna ◽  
Dna Methylation Age ◽  
Vietnam War Veterans ◽  
Sperm Dna Methylation
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