Role of the Bispectral Index in Sedation Monitoring in the ICU

2006 ◽  
Vol 40 (3) ◽  
pp. 490-500 ◽  
Author(s):  
Jaclyn M LeBlanc ◽  
Joseph F Dasta ◽  
Sandra L Kane-Gill
2014 ◽  
Vol 25 (3) ◽  
pp. 265-271 ◽  
Author(s):  
Eva Tschiedel ◽  
Oliver Müller ◽  
Ulrike Schara ◽  
Ursula Felderhoff-Müser ◽  
Christian Dohna-Schwake

2010 ◽  
Vol 2010 ◽  
pp. 1-5 ◽  
Author(s):  
Maria Sammartino ◽  
Barbara Volpe ◽  
Fabio Sbaraglia ◽  
Rossella Garra ◽  
Alessandro D'Addessi

Sedation in children is increasingly emerging as a minimally invasive technique that may be associated with local anaesthesia or diagnostic and therapeutic procedures which do not necessarily require general anaesthesia. Standard monitoring requirements are not sufficient to ensure an effective control of pulmonary ventilation and deep sedation. Capnography in pediatric sedation assesses the effect of different drugs on the occurrence of respiratory failure and records early indicators of respiratory impairment. The Bispectral index (BIS) allows the reduction of dose requirements of anaesthetic drugs, the reduction in the time to extubation and eye opening, and the reduction in the time to discharge. In the field of pediatric sedation, capnography should be recommended to prevent respiratory complications, particularly in spontaneous ventilation. The use of the BIS index, however, needs further investigation due to a lack of evidence, especially in infants. In this paper, we will investigate the role of capnography and the BIS index in improving monitoring standards in pediatric sedation.


Children ◽  
2021 ◽  
Vol 8 (8) ◽  
pp. 639
Author(s):  
Maximilian David Mauritz ◽  
Felix Uhlenberg ◽  
Eik Vettorazzi ◽  
Chinedu Ulrich Ebenebe ◽  
Dominique Singer ◽  
...  

We analyzed the impact of propofol administration during continuous sedation and analgesia on the nociceptive flexion reflex threshold (NFRT) and Bispectral Index (BIS) in ventilated children. We examined patients who received propofol before planned endotracheal suctioning. Patients were clinically assessed using the modified Face, Legs, Activity, Cry, Consolability (mFLACC) scale and COMFORT-B (Comfort Behavior) scale. We continuously recorded the NFRT and BIS. We recorded 23 propofol administrations in eight patients with an average age of 8.6 ± 3.5 years. The median (minimum-maximum) scores for the mFLACC scale and COMFORT-B scale were 0 (0–5) and 6 (6–17), respectively, before the bolus. The administration of a weight-adjusted propofol bolus of 1.03 ± 0.31 mg/kg resulted in an increase in NFRT and burst-suppression ratio; BIS and electromyogram values decreased. Changes from baseline (95% CI) after propofol bolus administration were BIS −23.9 (−30.8 to −17.1), EMG -10.5 dB (−13.3 to −7.7), SR 14.8 % (5.6 to 24.0) and NFRT 13.6 mA (5.5 to 21.7). Further studies are needed to determine whether sedated children may benefit from objective pain and sedation monitoring with BIS and NFRT.


2001 ◽  
Vol 21 (9) ◽  
pp. 416-420
Author(s):  
Masayasu NAKAYAMA ◽  
Hiromichi ICHINOSE ◽  
Shuji YAMAMOTO ◽  
Ken-ichi NAKABAYASHI ◽  
Michiko HAYASHI ◽  
...  

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