scholarly journals Evaluating the Comparative Values of Lipid Profile among Premenopausal and Postmenopausal Women

2017 ◽  
Vol 5 (1) ◽  
pp. 1-5
Author(s):  
Muhammad Ahmed Alamgir ◽  
Ishfaq Ahmed ◽  
Hashim Raza ◽  
Faridudin Faridudin
2012 ◽  
Vol 52 (12) ◽  
pp. 1852-1860 ◽  
Author(s):  
Lauren Nicole Bell ◽  
Anne Thi Phuong Nguyen ◽  
Lang Li ◽  
Zeruesenay Desta ◽  
N. Lynn Henry ◽  
...  

2016 ◽  
Vol 28 (6) ◽  
pp. 412 ◽  
Author(s):  
Radojka Bijelic ◽  
Jagoda Balaban ◽  
Snjezana Milicevic

2017 ◽  
Vol 12 (3) ◽  
Author(s):  
Lady Gwendoline Akwa ◽  
Monday Omoniyi Moses ◽  
Abigael Omowumi Emikpe ◽  
Biggie Baffour-Awuah ◽  
Benjamin Asamoah ◽  
...  

2016 ◽  
Vol 57 (8) ◽  
pp. 891-904 ◽  
Author(s):  
Magdalena Gibas-Dorna ◽  
Jacek Piątek ◽  
Justyna Kupsz ◽  
Malgorzata Bernatek ◽  
Hanna Krauss ◽  
...  

2009 ◽  
Vol 161 (5) ◽  
pp. 723-729 ◽  
Author(s):  
Mi Zhou ◽  
Xiaojing Ma ◽  
Huating Li ◽  
Xiaoping Pan ◽  
Junling Tang ◽  
...  

ObjectivesOsteocalcin, a bone-derived protein, has recently been reported to affect energy metabolism. We investigated the relationship between serum osteocalcin and parameters of adiposity, glucose tolerance, and lipid profile in Chinese subjects.MethodsSerum osteocalcin was measured by electrochemiluminescence immunoassay in 254 men (128 with newly diagnosed type 2 diabetes mellitus (T2DM) and 126 with normal glucose tolerance (NGT)), 66 premenopausal women (33 with T2DM and 33 with NGT) as well as 180 postmenopausal women (92 with T2DM and 88 with NGT). Their associations with parameters of adiposity, glucose tolerance, and lipid profile were examined.ResultsSerum osteocalcin concentrations in diabetic patients were significantly lower than those in NGT subjects after adjusted for age, gender, and body mass index (P=0.003). Postmenopausal women had higher osteocalcin concentrations than premenopausal women and men (both P<0.001). Multiple stepwise regression analysis showed that age, %fat, high-density lipoprotein cholesterol, fasting plasma glucose, and fasting serum insulin were independently associated with osteocalcin in men (P<0.05). Age and HbA1c were independently correlated with osteocalcin in postmenopausal women. Besides age and HbA1c, serum triglyceride was also an independent factor influencing osteocalcin in premenopausal women. In addition, osteocalcin was also positively associated with homeostasis model assessment of β-cell function. Furthermore, multiple logistic regression analysis demonstrated that osteocalcin was independently associated with T2DM.ConclusionsSerum osteocalcin was closely associated with not only fat and glucose metabolism but also with lipid metabolism.


2020 ◽  
Vol 79 (OCE2) ◽  
Author(s):  
Agata Muzsik ◽  
Agata Chmurzynska

AbstractIt has been hypothesized that insufficiency of one-carbon metabolism may aggravate lipid metabolism disturbances. Lipid metabolism abnormalities and metabolic syndrome (MetS)—which is associated with abnormally high levels of triglycerides (TG) and low levels of high-density lipoproteins (HDL)—often occur in postmenopausal women. The purpose of this study was thus to determine the relationships between amino acid and B vitamin intake, MTHFR genotype, lipid profile, and atherogenic indices in postmenopausal women.131 postmenopausal women were enrolled for the study. The mean macronutrient, amino acid, and B vitamin intake was evaluated using dietary records. Lipid profile and concentrations of apolipoprotein A1 (ApoA1) and B (ApoB) in serum were measured using the colorimetric method. The total homocysteine (tHcy) and glutathione (GSH) level in plasma were measured using high-performance liquid chromatography. MTHFR genotype (rs1801133) was determined using a single tube TaqMan SNP Genotyping Assay. We calculated atherogenic indices, such as Castelli's risk index I and II (CRI-I and CRI-II), the atherogenic coefficient (AC), and the TG/HDL ratio.No association was found between MetS and tHcy or GSH concentrations. MTHFR genotype and folate intake also did not affect tHcy, GSH, lipid profile, or atherogenic indices. Subjects with tHcy levels over the median had lower total protein intake, lower animal protein/plant protein ratio, lower protein/carbohydrates ratio, and higher amino acid intake (methionine, lysine, arginine, glycine, and tryptophan) than did subjects with lower tHcy levels. Women who failed to meet their vitamin B12 intake needs had almost 40% higher levels of tHcy than women who did met those needs.MTHFR genotype, folate intake, and tHcy levels in plasma are not associated with lipid metabolism in postmenopausal women. tHcy levels may depend on the intake of vitamin B12, and of protein or particular amino acids.The project was financed by the National Science Centre, Poland (grant number 2015/17/N/NZ9/04133).


2017 ◽  
Vol 11 ◽  
pp. 117954681773111 ◽  
Author(s):  
Lúcia Helena Bonalume Tácito ◽  
Lilian Nakachima Yamada ◽  
Marcela Augusta de Souza Pinhel ◽  
Juan Carlos Yugar-Toledo ◽  
Dorotéia Rossi Silva Souza

This study confirms the association of risk factors for coronary artery disease (CAD) and the apoE polymorphisms, specifically related to the APOE*4 allele, with coronary disease in postmenopausal women. Significantly altered values of the lipid profile were found in patients when compared with controls, independent of the presence of the APOE*4 allele. However, the controls showed higher high-density lipoprotein cholesterol (HDL-C) levels and reduced triglyceride (TG) levels, differing significantly from patients. In this case, the study of subgroups, considering the APOE*3/3 and APOE*3/4 genotypes, suggests that the APOE*4 allele is not implicated in the variations of the lipid profile of patients and determined an increase in the production levels of HDL-C and a reduction in TG highly benefiting the control group compared with APOE*3/3 genotype. The metabolic kinetics of TG, although with the same pattern between groups, and the presence of the APOE*4 allele are suggested to be associated with accelerated clearance compared with APOE*3 allele in non-CAD group.


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