scholarly journals Improving Cardiovascular Risk Profiles in Firefighters

2016 ◽  
Vol 4 (3) ◽  
pp. 32-35
Author(s):  
Paige Wimberley
Keyword(s):  
Cardiovascular Risk ◽  
Risk Profiles

Abstract TP207: Sex Differences in Cardiovascular Risk Profiles of Patients with Diabetes in the Greater Cincinnati/ Northern Kentucky Stroke Study

Stroke ◽  
2017 ◽  
Vol 48 (suppl_1) ◽  
Author(s):  
Tracy E Madsen ◽  
Jane C Khoury ◽  
Kathleen Alwell ◽  
Charles J Moomaw ◽  
Stacie L Demel ◽  
...  
Keyword(s):  
Cardiovascular Risk ◽  
Stroke Risk ◽  
Negative Impact ◽  
Age Difference ◽  
Risk Profiles ◽  
Chi Square ◽  
Adult Age ◽  
Stroke Study ◽  
Patients With Diabetes ◽  
History Of

Introduction: Diabetes mellitus (DM) carries a greater stroke risk for females than males, possibly because of a difference in cardiovascular risk profiles between females and males with DM. Our aim was to compare the sex-specific risk factor profiles for patients with DM with those without DM among patients with acute ischemic stroke (AIS) in the Greater Cincinnati/ Northern Kentucky Stroke Study (GCNKSS). Methods: The GCNKSS ascertained cases of AIS in 2005 and 2010 among adult (age ≥20 years) residents of a biracial population of 1.3 million. Past and current stroke risk factors, obtained via chart review, were compared between those with and without DM using chi-square to examine bivariate differences and multiple logistic regression to examine sex-specific profiles. P < 0.05 was considered statistically significant. Results: There were 3515 patients with incident AIS; 1919 (55%) were female, 697 (20%) were black, and 1146 (33%) had DM. A lower proportion of females with DM were over 65 years old compared with those without DM. The proportion of males >65 with DM was not significantly different from that of males without DM. Among both females and males with DM, significantly more were Black, obese, and had histories of hypertension, high cholesterol, CAD and myocardial infarction compared to those without DM. In sex-specific adjusted analyses, women with DM were significantly less likely to be over 65 and more likely to have CAD than women without DM, whereas age and CAD were not significant factors in differentiating the profiles of men with and without DM. Conclusions: The result that females had their strokes at a younger age if they had a history of DM, and that no such age difference existed in males, suggests that DM is more severe and has a greater negative impact on females than males. As opposed to males, females with DM were also more likely to have CAD compared to those without DM, consistent with a possible sex difference in the association between DM and vascular disease.

Older Statin Initiators in Finland—Cardiovascular Risk Profiles and Persistence of Use

2014 ◽  
Vol 28 (3) ◽  
pp. 263-272 ◽  
Author(s):  
Eveliina Upmeier ◽  
Maarit Jaana Korhonen ◽  
Maria Rikala ◽  
Arja Helin-Salmivaara ◽  
Risto Huupponen
Keyword(s):  
Cardiovascular Risk ◽  
Risk Profiles

scholarly journals LEADER 7: cardiovascular risk profiles of US and European participants in the LEADER diabetes trial differ

2016 ◽  
Vol 8 (1) ◽  
Author(s):  
Guy E. H. M. Rutten ◽  
◽  
Cees J. Tack ◽  
Thomas R. Pieber ◽  
Abdurrahman Comlekci ◽  
...  
Keyword(s):  
Cardiovascular Risk ◽  
Risk Profiles

1060 PREVALENCE OF CARDIOVASCULAR RISK PROFILES IN MALAYSIAN POPULATION AMONG MALES AND FEMALES

2012 ◽  
Vol 30 (Supplement 1) ◽  
pp. e308
Author(s):  
Najmin Abu Bakar ◽  
Fadhlina Abd Majid ◽  
Mohd Yazrie Yaacob ◽  
Rafezah Razali ◽  
Maizatullifah Miskan ◽  
...  
Keyword(s):  
Cardiovascular Risk ◽  
Risk Profiles ◽  
Malaysian Population ◽  
Males And Females

Cardiovascular risk profiles in German Air Force pilots

2020 ◽  
pp. bmjmilitary-2020-001608
Author(s):  
Stefan Sammito ◽  
N Güttler
Keyword(s):  
Cardiovascular Risk ◽  
Total Cholesterol ◽  
Antihypertensive Drugs ◽  
Smoking Status ◽  
Positive Family History ◽  
Density Lipoprotein ◽  
Armed Forces ◽  
Risk Profiles ◽  
German Armed Forces ◽  
Military Pilots

IntroductionCardiovascular disease (CVD) is the leading cause of death in western industrial countries and one of the most frequent causes of sudden incapacitation in flight for pilots. There are limited data available on cardiovascular risk profiles of pilots, and especially military pilots. The aim of this study was to assess the prevalence of cardiovascular risk factors (CVRF) in German military pilots.MethodsThe changing prevalence of CVRF in active military pilots was studied using a cross-sectional survey during two distinct periods, 2007–2009 and 2016–2018. Data collected included sex, body mass index (BMI), smoking status, resting blood pressure, total cholesterol, high density lipoprotein (HDL), low density lipoprotein (LDL), triglycerides and glucose. The use of antihypertensive drugs, diagnosis of diabetes mellitus and positive family history of myocardial infarction were also captured. Based on these data, the PROCAM (Prospective Cardiovascular Münster) score was calculated.ResultsData from 5353 flight medical examinations were analysed, 3397 from 2007 to 2009, and 1959 from 2016 to 2018. Between the cohorts, age, BMI, total cholesterol, HDL, LDL, glucose and triglycerides increased significantly. The number of pilots on antihypertensive medication decreased significantly. The PROCAM score increased between cohorts from 18 to 23 points predicting a 10-year risk of an acute coronary event of <1% and 1.3%, respectively.ConclusionThe German military pilot population has become older with increased CVRF. CVD will be a future challenge for the German Armed Forces and probably other military forces. However, there was only a mild increase of the PROCAM score over time.

P3447Multimodal assessment and phenomapping of early atherosclerosis in children with chronic disease

2019 ◽  
Vol 40 (Supplement_1) ◽  
Author(s):  
F A Ververs ◽  
A L M Eikendal ◽  
J J M Westenberg ◽  
R J Van Der Geest ◽  
R Nuboer ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cardiovascular Risk ◽  
Chronic Disease ◽  
Wall Thickness ◽  
Aortic Wall ◽  
Pulse Wave ◽  
Research Fund ◽  
Risk Profiles ◽  
Aortic Wall Thickness ◽  
Early Atherosclerosis

Abstract Background Childhood survival of chronic disease steadily increased over the last decades. However, accumulating evidence suggests that survivors are at risk for early atherosclerosis. The “Cardiovascular Disease in Children with chronic disease” (CDC) study has two aims. First, multimodal assessment of early atherosclerosis was performed in adolescents with chronic inflammatory- and metabolic disorders in order to develop new diagnostic approaches. As fatty streak formation starts in the abdominal aorta, aortic wall thickness (AWT) and pulse wave velocity (PWV) were measured using cardiovascular magnetic resonance imaging (MRI), and compared with traditional carotid intima-media thickness (cIMT) and echocardiography. Second, comprehensive risk profiling was performed, including phenomapping of early risk factors, in order to establish cardiovascular risk profiles in childhood. Methods 113 adolescents aged 12–19 years old were enrolled*. The study population includes adolescents with juvenile idiopathic arthritis (JIA, n=19), cystic fibrosis (CF, n=24), obesity (n=20), corrected coarctation of the aorta (CoA, n=25), and corrected atrial septal defect as control group (ASD, n=25). The aorta was imaged on a 3.0 Tesla MR system using the 3D-T1-BB-VISTA sequence. Aortic PWV was assessed using velocity-encoded MRI. cIMT was measured in three directions for both the right- and left carotid artery using echography. Unbiased hierarchical clustering was performed on phenotypic data (phenomapping), including anthropomorphic-, metabolic-, and inflammatory parameters. Results* Aortic pulse wave velocity on MRI was highest in the obese group compared to controls (p=0.002), yet JIA patients (p=0.015), CoA patients (p=0.029), and CF patients (p=0.044) also showed increased PWV compared to controls. Aortic wall thickness was highest in obese adolescents (p=0.020) and in CF patients (p=0.043). cIMT was only increased in CoA patients (p=0.000). While PWV and AWT showed correlation with inflammatory- and metabolic parameters such as lymphocyte count (PWV, p=0.043), monocyte count (PWV, p=0.002; AWT, p=0.036), CRP (AWT, p=0.032), and QUICKI (PWV, p=0.026), cIMT correlated with systolic blood pressure (p=0.017). Phenomapping of risk factors will further define distinct cardiovascular risk profiles*. Conclusion Multimodal assessment of early atherosclerosis in children with chronic disease reveals differential vascular changes. While traditional cIMT is associated with increased systolic blood pressure in young CoA patients, aortic PWV and aortic wall thickness reflect early systemic inflammatory- and metabolic derangement. Phenomapping traditional risk factors alongside inflammatory- and metabolic parameters bears promise to establish early cardiovascular risk profiles in childhood chronic disease*. *Patient inclusion finishes May 2019, followed by phenomapping of patient characteristics. At the ESC, final data will be presented. Acknowledgement/Funding Wilhelmina Children's Hospital Research Fund, Dutch Topsector Life Sciences and Health TKI fund, Nutricia Research fund. HS was supported by VENI-NWO.

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