scholarly journals Phytochemical Composition and Evaluation of Anti-Inflammatory Activity in Glycosmis pentaphylla (Retz.)DC. - An Ethnobotanically Important Medicinal Plant

2020 ◽  
Vol 8 (3) ◽  
pp. 109-115
Author(s):  
Vinitha S Babu ◽  
P M Radhamany
2021 ◽  
Vol 11 (20) ◽  
pp. 9697
Author(s):  
Eduardo Padilla-Camberos ◽  
Omar Ricardo Torres-Gonzalez ◽  
Ivan Moises Sanchez-Hernandez ◽  
Nestor Emmanuel Diaz-Martinez ◽  
Oscar Rene Hernandez-Perez ◽  
...  

Nowadays, there is a growing interest in the development of medicinal plant-based therapies to diminish the ravages of the inflammatory process related to diseases and tissue damage. Most therapeutic effects of these traditional medicinal plants are owed to their phenolic and antioxidant properties. C. aconitifolius is a traditional medicinal plant in Mexico. Previous characterization reports have stated its high nutritional and antioxidant components. The present study aimed to better understand the biological activity of C. aconitifolius in inflammation response. We developed an ethyl acetate extract of this plant to evaluate its anti-inflammatory capacity and its flavonoid content. The topical anti-inflammatory effect of the ethyl acetate extract of C. aconitifolius was determined by the croton oil-induced mouse ear edema test, while flavonoid detection and concentration were determined by thin layer chromatography and the aluminum chloride colorimetric assay, respectively. Topical application of the extract showed significant inhibition of the induced-ear edema (23.52 and 49.41% for 25 and 50 mg/kg dose, respectively). The extract also exhibited the presence of flavonoids. The finding of the anti-inflammatory activity exerted by the C. aconitifolius and the identification of its active principles may suggest and support its use for inflammation treatment.


2018 ◽  
Vol 8 (5) ◽  
pp. 88-91
Author(s):  
Aisha Siddiqui ◽  
Zeba Afrin ◽  
MA Jafri

Lavandula stoechas Mill. commonly known as Ustukhudoos, is perhaps the most important medicinal plant in the unani system of medicine. Whole part, flowers and essential oil of the plant is used to treat a variety of diseases. A number of ailments are treated by the plant which is used either alone or in combination with other plants. It is used for the treatment of various neurological disorders like hemiplegia, facial paralysis, tremors, epilepsy, melancholia, neurasthenia. Moreover, it is used in sinusitis, liver disorders and urinary disorders etc. L. stoechas possesses antimicrobial, antidiabetic, antioxidant, antifungal, anti-inflammatory, anticonvulsant, antispasmodic, sedative, hepatoprotective activities. This article discusses and summarizes the important medicinal values of Ustukhudoos in the perspective of Unani literature as well as modern scientific research. Keywords: Ustukhudoos, Lavandula stoechas, neurological, epilepsy


2013 ◽  
Vol 2013 ◽  
pp. 1-4 ◽  
Author(s):  
Cuauhtemoc Pérez González ◽  
Roberto Serrano Vega ◽  
Marco González-Chávez ◽  
Miguel Angel Zavala Sánchez ◽  
Salud Pérez Gutiérrez

We investigated the anti-inflammatory activity ofSenecio salignus. This medicinal plant is often used in Mexico for the treatment of fever and rheumatism. Chloroform and methanol extracts of the plant were tested on 12-O-tetradecanoylphorbol-13-acetate- (TPA-) induced edema in mice ears. The methanol extract of the plant inhibited edema by36±4.4% compared with the control, while the chloroform extract exhibited an even greater level of inhibition (64.1%). The chloroform extract was then fractionated, and the composition of the active fraction was determined by GC-MS. The anti-inflammatory activity of this fraction was then tested on TPA-induced ear edema in mice, and we found that the active fraction could inhibit edema by 46.9%. The anti-inflammatory effect of the fraction was also tested on carrageenan-induced paw edema in rats at doses of 100 mg/kg; a58.9±2.8% reduction of the edema was observed 4 h after administration of carrageenan, and the effect was maintained for 5 h.


2017 ◽  
Vol 55 (1) ◽  
pp. 1553-1560 ◽  
Author(s):  
Mimoza Basholli-Salihu ◽  
Roswitha Schuster ◽  
Avni Hajdari ◽  
Dafina Mulla ◽  
Helmut Viernstein ◽  
...  

2014 ◽  
Vol 9 (1) ◽  
pp. 1934578X1400900 ◽  
Author(s):  
Angel Jardón-Delgado ◽  
Gil Alfonso Magos-Guerrero ◽  
Mariano Martínez-Vázquez

A new cucurbitane-type triterpene, 20, 21, 22, 23, 24, 25, 26, 27-octanorcucurbita-5-ene-3, 11, 16-trione (1), named kinoin D, was isolated from the roots of the medicinal plant Ibervillea sonorae, (wereque). The structure of 1 was established on the basis of extensive NMR and MS studies. In addition, the known kinoins B (3) and C (5) were isolated, as were 16α-20,25-trihydroxy-3α-(2- O-α-L-rhamnopyranosiyl-D-glucopyranosyloxy)-(10α)-cucurbit-5-en-11,22-dione (6), (22 S)-16α,22-diacetoxy-20,25-dihydroxy-3α-[3,4,6-tri- O-acetyl-2- O-(2,3,4-tri- O-acetyl-α-L-rhamnopyranosyl)-β-glucopyranosyl]-(10α)-cucurbita-5,23t-dien-11-one (7) and 16α-acetoxy-20,25-dihydroxy-3α-[3,4,6-tri- O-acetyl-2- O-(2,3,4,-tri- O-acetyl-α-L-rhamnopyranosyl)-β-D-glucopyranosyl]-(10α)-cucurbita-5-ene-11,22-dione (8). Compound 1 exhibited anti-inflammatory activity in TPA-induced edema in mice.


Author(s):  
AMALA DIVYA S. ◽  
THAMARAIKANI V. ◽  
SEKAR T.

Objective: Sarcostemma brunonianum Wight and Arn is a potential medicinal plant belonging to Asclepiadaceae. Bioactive constituents of the plant support the application of treating various ailments in the traditional system of medicine. The study aims to determine the presence of various phytoconstituents in stem, root, and flowers. Methods: Hot percolation method was carried out to obtain crude extracts using different solvent systems from low polar-high polar solvents ranging from petroleum ether, chloroform, (mid-polar) ethyl acetate, methanol and water. Estimation of total phenols, tannins and In vitro antioxidant, anti-inflammatory activities were evaluated for the determination of potential pharmaceutical drugs. Results: The results revealed the presence of some phytoconstituents such as phenols, tannins, glycosides, gums and mucilages. Ascorbic acid, BSA, Rutin and Gallic acid were used as the reference standard. The total phenolic content was found to be high in stem methanol extract 440.84±69.99 mg/g Gallic acid equivalent, whereas the tannin content was 291.78±4.68 mg/g GAE. The result proves that the S. brunonianum stem methanol extract possesses antioxidant and anti-inflammatory activities when compared to reference standards. In vitro, Nitric oxide scavenging activity of stem showed a maximum % of inhibition in methanol stem extract (24.39µg/ml) and anti-inflammatory activity maximum inhibition was found to be (55.56 %) in stem methanol and flower(53.62 %). The IC50 (concentration required for 50% inhibition) was also calculated for the DPPH radical model. Conclusion: This study results proclaims and justifies the role of folklore medicinal plant S. brunonianum in the treatment of inflammatory-related ailments and can be recommended for an effective drug.


Author(s):  
G. Kokila ◽  
P. Jeevan

In the present study we evaluate the antibacterial, anti-inflammatory and antioxidant activity of medicinal plant Ipomoea staphylina Roem & Schult. Many bacteria are harmful to human beings and animals. Theses bacteria make diseases the host organisms. Many antibiotics are available in the marker for the treatment of bacterial diseases. However, antibiotics cause unwanted side effect. Thus, the study focused to evaluate ethanol extract of Ipomoea staphylina against bacterial pathogens. Antibacterial activity was evaluated by the method of well diffusion method. Antiinflamatory and antioxidant activity was evaluated by in vitro study method. Ethanol extract of Ipomoea staphylina showed antibacterial activity against different bacteria isolated from chicken at dose depended manner ie., higher dose of plant extract possessed maximum inhibition zone (21.67 ± 1.45 mm) (P<0.05) against selected bacteria. Moreover, plant ethanol extract possessed anti-inflammatory activity and antioxidant activity at dose dependent manner (P<0.05). Higher dose (100 μg/ml) of ethanol extract of Ipomoea staphylina showed maximum anti-inflammatory activity (68.38 %) and antioxidant activity (72%). From this result it is concluded that the medicinal plant Ipomoea staphylina Roem. & Schult. possessed antibacterial, anti-inflammatory and antioxidant activity. Further detailed study will be conducted for the new drug candidate discovery.


1984 ◽  
Vol 11 (3) ◽  
pp. 319-330 ◽  
Author(s):  
R.S. Saxena ◽  
B. Gupta ◽  
K.K. Saxena ◽  
R.C. Singh ◽  
D.M. Prasad

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