Post-Irradiation Examination System Development for Irradiated Optical Components of In-Situ Spectroscopic Sensors

2020 ◽  
Author(s):  
I. Jovanovic ◽  
M. Burge ◽  
P. Skrodzki ◽  
P. Marotta ◽  
P. Sabharwall ◽  
...  
Keyword(s):  
System Development ◽  
Examination System ◽  
Optical Components ◽  
Post Irradiation ◽  
Spectroscopic Sensors

scholarly journals In-situ K-Ar dating on Mars based on UV-Laser ablation coupled with a LIBS-QMS system: Development, calibration and application of the KArMars instrument

2019 ◽  
Vol 506 ◽  
pp. 1-16 ◽  
Author(s):  
Fanny Cattani ◽  
Pierre-Yves Gillot ◽  
Xavier Quidelleur ◽  
Anthony Hildenbrand ◽  
Jean-Claude Lefèvre ◽  
...  
Keyword(s):  
Laser Ablation ◽  
System Development ◽  
Uv Laser

scholarly journals The Rise of the OM-LoC: Opto-Microfluidic Enabled Lab-on-Chip

Micromachines ◽  
2021 ◽  
Vol 12 (12) ◽  
pp. 1467
Author(s):  
Harry Dawson ◽  
Jinane Elias ◽  
Pascal Etienne ◽  
Sylvie Calas-Etienne
Keyword(s):  
Low Cost ◽  
Optical Components ◽  
New Era ◽  
Lab On Chip ◽  
Highly Sensitive ◽  
Multiple Challenges ◽  
On Chip ◽  
Optical Circuits ◽  
Made In

The integration of optical circuits with microfluidic lab-on-chip (LoC) devices has resulted in a new era of potential in terms of both sample manipulation and detection at the micro-scale. On-chip optical components increase both control and analytical capabilities while reducing reliance on expensive laboratory photonic equipment that has limited microfluidic development. Notably, in-situ LoC devices for bio-chemical applications such as diagnostics and environmental monitoring could provide great value as low-cost, portable and highly sensitive systems. Multiple challenges remain however due to the complexity involved with combining photonics with micro-fabricated systems. Here, we aim to highlight the progress that optical on-chip systems have made in recent years regarding the main LoC applications: (1) sample manipulation and (2) detection. At the same time, we aim to address the constraints that limit industrial scaling of this technology. Through evaluating various fabrication methods, material choices and novel approaches of optic and fluidic integration, we aim to illustrate how optic-enabled LoC approaches are providing new possibilities for both sample analysis and manipulation.

scholarly journals Vitamin E is necessary for zebrafish nervous system development

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Brian Head ◽  
Jane La Du ◽  
Robyn L. Tanguay ◽  
Chrissa Kioussi ◽  
Maret G. Traber
Keyword(s):  
Nervous System ◽  
Vitamin E ◽  
System Development ◽  
Regulatory Protein ◽  
Nervous System Development ◽  
Developmental Defects ◽  
Transfer Protein ◽  
Rna In Situ Hybridization ◽  
Brain Ventricle

Abstract Vitamin E (VitE) deficiency results in embryonic lethality. Knockdown of the gene ttpa encoding for the VitE regulatory protein [α-tocopherol transfer protein (α-TTP)] in zebrafish embryos causes death within 24 h post-fertilization (hpf). To test the hypothesis that VitE, not just α-TTP, is necessary for nervous system development, adult 5D strain zebrafish, fed either VitE sufficient (E+) or deficient (E−) diets, were spawned to obtain E+ and E− embryos, which were subjected to RNA in situ hybridization and RT-qPCR. Ttpa was expressed ubiquitously in embryos up to 12 hpf. Early gastrulation (6 hpf) assessed by goosecoid expression was unaffected by VitE status. By 24 hpf, embryos expressed ttpa in brain ventricle borders, which showed abnormal closure in E− embryos. They also displayed disrupted patterns of paired box 2a (pax2a) and SRY-box transcription factor 10 (sox10) expression in the midbrain-hindbrain boundary, spinal cord and dorsal root ganglia. In E− embryos, the collagen sheath notochord markers (col2a1a and col9a2) appeared bent. Severe developmental errors in E− embryos were characterized by improper nervous system patterning of the usually carefully programmed transcriptional signals. Histological analysis also showed developmental defects in the formation of the fore-, mid- and hindbrain and somites of E− embryos at 24 hpf. Ttpa expression profile was not altered by the VitE status demonstrating that VitE itself, and not ttpa, is required for development of the brain and peripheral nervous system in this vertebrate embryo model.

The role of comets and asteroids in Solar System development: space exploration

1994 ◽  
Vol 349 (1690) ◽  
pp. 323-334 ◽  
Keyword(s):  
Solar System ◽  
System Development ◽  
Space Exploration ◽  
Ground Truth ◽  
Interplanetary Dust ◽  
Calibration Data ◽  
Mixed Classes ◽  
Asteroids And Comets

Exploration by space missions of the near-nucleus regions of comets Halley and Grigg-Skjellerup has resulted in valuable but expensive snapshots of cometary phenomena. The ‘ground truth’ from such missions, which can be established only by this means of dedicated space exploration, provides essential inputs to models of cometary processes. It also gives calibration data for a very wide base of cometary and asteroidal observations, past, present and future. Seen as objects which are both eroded by impacts from interplanetary dust and also the progenitors of interplanetary dust, we find both asteroids and comets are needed to contribute to this population. Contrary to expectations, as new data on the asteroids and comets is analysed, we find the differences between the two classes of primordial body is very much less distinct; accounting for the interplanetary distribution and properties of dust mass requires not only both classes of object but also a distribution of mixed classes. ESA’s newly selected cometary mission Rosetta will offer a unique opportunity, during a rendezvous encounter from aphelion to perihelion, for the extended and detailed in situ observations of a target comet. It will also act as a valuable focus on the nature and role of comets in both the origin and development of the Solar System.

Microstructure and Post-Irradiation Annealing Behavior of 20% Cold-Worked 316 Stainless Steel

2000 ◽  
Vol 650 ◽  
Author(s):  
J. I. Cole ◽  
T. R. Allen ◽  
H. Kusanagi ◽  
K. Dohi ◽  
J. Ohta
Keyword(s):  
Stainless Steel ◽  
Cold Work ◽  
Microstructural Development ◽  
Dislocation Loops ◽  
Annealing Behavior ◽  
Post Irradiation ◽  
316 Stainless Steel ◽  
Dose Rates ◽  
Cold Worked

ABSTRACTMicrostructural examination and in situ post-irradiation annealing studies were carried out on 20% cold-worked 316 stainless steel (SS) hexagonal duct material following irradiation in the reflector region of the EBR-II reactor. Stainless steel hexagonal ducts were used to house reactor subassemblies and provide a valuable source of information on irradiation behavior of reactor structural materials at lower dose-rates (on the order of 10-8 dpa/sec) than previously examined. The microstructural development of samples irradiated to doses of 1, 20 and 30 dpa is examined, while the post-irradiation annealing behavior of a sample irradiated to 20 dpa is described. Annealing studies were performed at 370 and 500°C to examine the kinetics of radiation damage recovery as a function of annealing temperature. The initial (pre-annealed) microstructures consists of a substantial density of irradiation induced chromium-rich M23C6 and M6C carbides which form both on the grain boundaries and within the grain interiors. Recovery of the cold- work is evident in the 1 dpa sample while samples irradiated to 20 and 30 dpa possess dense populations of voids and dislocation structures consisting of networks of line dislocations and faulted dislocation loops. Results indicate that post-irradiation annealing of the samples at 370°C for 1 hour has little effect on the microstructure, while further annealing at 500°C for 1 hour results in void shrinkage, the formation of small cavities, and a reduction in the dislocation loop and network density.

Plastic deformation of SUS304 under in situ and post-irradiation fatigue loadings

2007 ◽  
Vol 367-370 ◽  
pp. 966-971 ◽  
Author(s):  
Y. Murase ◽  
Johsei Nagakawa ◽  
N. Yamamoto
Keyword(s):  
Plastic Deformation ◽  
Post Irradiation

The materials science X-ray beamline BL8 at the DELTA storage ring

2009 ◽  
Vol 16 (2) ◽  
pp. 264-272 ◽  
Author(s):  
Dirk Lützenkirchen-Hecht ◽  
Ralph Wagner ◽  
Ulrich Haake ◽  
Anke Watenphul ◽  
Ronald Frahm
Keyword(s):  
Materials Science ◽  
Photon Flux ◽  
Acquisition Time ◽  
Optical Components ◽  
Time Resolved ◽  
X Ray ◽  
Heavy Loads ◽  
Vacuum Systems ◽  
X Ray Absorption

The hard X-ray beamline BL8 at the superconducting asymmetric wiggler at the 1.5 GeV Dortmund Electron Accelerator DELTA is described. This beamline is dedicated to X-ray studies in the spectral range from ∼1 keV to ∼25 keV photon energy. The monochromator as well as the other optical components of the beamline are optimized accordingly. The endstation comprises a six-axis diffractometer that is capable of carrying heavy loads related to non-ambient sample environments such as, for example, ultrahigh-vacuum systems, high-pressure cells or liquid-helium cryostats. X-ray absorption spectra from several reference compounds illustrate the performance. Besides transmission measurements, fluorescence detection for dilute sample systems as well as surface-sensitive reflection-mode experiments have been performed. The results show that high-quality EXAFS data can be obtained in the quick-scanning EXAFS mode within a few seconds of acquisition time, enabling time-resolved in situ experiments using standard beamline equipment that is permanently available. The performance of the new beamline, especially in terms of the photon flux and energy resolution, is competitive with other insertion-device beamlines worldwide, and several sophisticated experiments including surface-sensitive EXAFS experiments are feasible.

scholarly journals Single-nanowire spectrometers

Science ◽  
2019 ◽  
Vol 365 (6457) ◽  
pp. 1017-1020 ◽  
Author(s):  
Zongyin Yang ◽  
Tom Albrow-Owen ◽  
Hanxiao Cui ◽  
Jack Alexander-Webber ◽  
Fuxing Gu ◽  
...  
Keyword(s):  
Single Cell ◽  
Spectral Response ◽  
Spectral Imaging ◽  
Visible Range ◽  
Response Functions ◽  
In Situ Characterization ◽  
Optical Components ◽  
Wide Range ◽  
Current Systems

Spectrometers with ever-smaller footprints are sought after for a wide range of applications in which minimized size and weight are paramount, including emerging in situ characterization techniques. We report on an ultracompact microspectrometer design based on a single compositionally engineered nanowire. This platform is independent of the complex optical components or cavities that tend to constrain further miniaturization of current systems. We show that incident spectra can be computationally reconstructed from the different spectral response functions and measured photocurrents along the length of the nanowire. Our devices are capable of accurate, visible-range monochromatic and broadband light reconstruction, as well as spectral imaging from centimeter-scale focal planes down to lensless, single-cell–scale in situ mapping.

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