Authenticating Powdered Foods and Ingredients using a High-throughput Raman Chemical Imaging Method

2014 ◽  
Keyword(s):  
High Throughput ◽  
Chemical Imaging ◽  
Imaging Method ◽  
Raman Chemical Imaging

Evaluation of a high-throughput liquid crystal tunable filter for Raman chemical imaging of threat materials

2006 ◽  
Author(s):  
Xinghua Wang ◽  
Thomas C. Voigt ◽  
Philip J. Bos ◽  
Matthew P. Nelson ◽  
Patrick J. Treado
Keyword(s):  
Liquid Crystal ◽  
High Throughput ◽  
Chemical Imaging ◽  
Tunable Filter ◽  
Raman Chemical Imaging

Detection and quantification of adulterants in milk powder using a high-throughput Raman chemical imaging technique

2016 ◽  
Vol 34 (2) ◽  
pp. 152-161 ◽  
Author(s):  
Jianwei Qin ◽  
Moon S. Kim ◽  
Kuanglin Chao ◽  
Sagar Dhakal ◽  
Hoonsoo Lee ◽  
...  
Keyword(s):  
High Throughput ◽  
Imaging Technique ◽  
Milk Powder ◽  
Chemical Imaging ◽  
Raman Chemical Imaging ◽  
Detection And Quantification

Quantitative Detection of Benzoyl Peroxide in Wheat Flour Using Line-Scan Macroscale Raman Chemical Imaging

2017 ◽  
Vol 71 (11) ◽  
pp. 2469-2476 ◽  
Author(s):  
Jianwei Qin ◽  
Moon S. Kim ◽  
Kuanglin Chao ◽  
Maria Gonzalez ◽  
Byoung-Kwan Cho
Keyword(s):  
Benzoyl Peroxide ◽  
Wheat Flour ◽  
Imaging System ◽  
Limit Of Detection ◽  
Chemical Imaging ◽  
Quantitative Detection ◽  
Imaging Method ◽  
Powdered Sample ◽  
Line Scan ◽  
Raman Chemical Imaging

A high-throughput Raman chemical imaging method was developed for direct inspection of benzoyl peroxide (BPO) mixed in wheat flour. A 5 W, 785 nm line laser (240 mm long and 1 mm wide) was used as a Raman excitation source in a push-broom Raman imaging system. Hyperspectral Raman images were collected in a wavenumber range of 103–2881 cm−1 from dry wheat flour mixed with BPO at eight concentrations (w/w) from 50 to 6400 ppm. A sample holder with a sampling volume of 150 × 100 × 2 mm3 was used to present a thin layer (2 mm thick) of the powdered sample for line-scan image acquisition with a spatial resolution of 0.2 mm. A baseline correction method based on adaptive iteratively reweighted penalized least squares was used to remove the fluctuating fluorescence signals from the wheat flour. To isolate BPO particles from the flour background, a simple thresholding method was applied to the single-band fluorescence-free images at a unique Raman peak wavenumber (i.e., 1001 cm−1) preselected for the BPO detection. Chemical images were created to detect and map the BPO particles. Limit of detection for the BPO was estimated in the order of 50 ppm, which is on the same level with regulatory standards. Pixel concentrations were calculated from the percentages of the BPO pixels in the chemical images. High correlation was found between the pixel concentrations and the mass concentrations of the BPO, indicating that the Raman chemical imaging method can be used for quantitative detection of the BPO mixed in the wheat flour.

A Line-Scan Hyperspectral System for High-Throughput Raman Chemical Imaging

2014 ◽  
Vol 68 (6) ◽  
pp. 692-695 ◽  
Author(s):  
Jianwei Qin ◽  
Kuanglin Chao ◽  
Moon S. Kim
Keyword(s):  
High Throughput ◽  
Chemical Imaging ◽  
Line Scan ◽  
Raman Chemical Imaging

scholarly journals Real-time imaging of cellular forces using optical interference

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Andrew T. Meek ◽  
Nils M. Kronenberg ◽  
Andrew Morton ◽  
Philipp Liehm ◽  
Jan Murawski ◽  
...  
Keyword(s):  
Cell Culture ◽  
Real Time ◽  
High Throughput ◽  
Mechanical Activity ◽  
Dynamic Processes ◽  
Imaging Method ◽  
Neonatal Cardiomyocytes ◽  
A Cell ◽  
Cellular Forces ◽  
Time Acquisition

AbstractImportant dynamic processes in mechanobiology remain elusive due to a lack of tools to image the small cellular forces at play with sufficient speed and throughput. Here, we introduce a fast, interference-based force imaging method that uses the illumination of an elastic deformable microcavity with two rapidly alternating wavelengths to map forces. We show real-time acquisition and processing of data, obtain images of mechanical activity while scanning across a cell culture, and investigate sub-second fluctuations of the piconewton forces exerted by macrophage podosomes. We also demonstrate force imaging of beating neonatal cardiomyocytes at 100 fps which reveals mechanical aspects of spontaneous oscillatory contraction waves in between the main contraction cycles. These examples illustrate the wider potential of our technique for monitoring cellular forces with high throughput and excellent temporal resolution.

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