Modeling Receptor Odor Exposure from Swine Production Sources Using CAM

2008 ◽  
Vol 24 (6) ◽  
pp. 821-837 ◽  
Author(s):  
S. J. Hoff ◽  
D. S. Bundy ◽  
J. D. Harmon
2021 ◽  
Vol 17 (1) ◽  
Author(s):  
Hideki Kashiwadani ◽  
Yurina Higa ◽  
Mitsutaka Sugimura ◽  
Tomoyuki Kuwaki

AbstractWe had recently reported that linalool odor exposure induced significant analgesic effects in mice and that the effects were disappeared in olfactory-deprived mice in which the olfactory epithelium was damaged, thus indicating that the effects were triggered by chemical senses evoked by linalool odor exposure. However, the peripheral neuronal mechanisms, including linalool receptors that contribute toward triggering the linalool odor-induced analgesia, still remain unexplored. In vitro studies have shown that the transient receptor potential ankyrin 1 (TRPA1) responded to linalool, thus raising the possibility that TRPA1 expressed on the trigeminal nerve terminal detects linalool odor inhaled into the nostril and triggers the analgesic effects. To address this hypothesis, we measured the behavioral pain threshold for noxious mechanical stimulation in TRPA1-deficient mice. In contrast to our expectation, we found a significant increase in the threshold after linalool odor exposure in TRPA1-deficient mice, indicating the analgesic effects of linalool odor even in TRPA1-deficient mice. Furthermore, intranasal application of TRPA1 selective antagonist did not alter the analgesic effect of linalool odor. These results showed that the linalool odor-induced analgesia was triggered by a TRPA1-independent pathway in mice.


Atmosphere ◽  
2021 ◽  
Vol 12 (3) ◽  
pp. 371
Author(s):  
Yan Zhang ◽  
Weihua Yang ◽  
Günther Schauberger ◽  
Jianzhuang Wang ◽  
Jing Geng ◽  
...  

Municipal wastewater treatment plants (WWTPs) inside cities have been the major complained sources of odor pollution in China, whereas there is little knowledge about the dose–response relationship to describe the resident complaints caused by odor exposure. This study explored a dose–response relationship between the modelled exposure and the annoyance surveyed by questionnaires. Firstly, the time series of odor concentrations were preliminarily simulated by a dispersion model. Secondly, the perception-related odor exposures were further calculated by combining with the peak to mean factors (constant value 4 (Germany) and 2.3 (Italy)), different time periods of “a whole year”, “summer”, and “nighttime of summer”, and two approaches of odor impact criterion (OIC) (“odor-hour” and “odor concentration”). Thirdly, binomial logistic regression models were used to compare kinds of perception-related odor exposures and odor annoyance by odds ratio, goodness of fit and predictive ability. All perception-related odor exposures were positively associated with odor annoyance. The best goodness of fit was found when using “nighttime of summer” in predicting odor-annoyance responses, which highlights the importance of the time of the day and the time of the year weighting. The best predictive performance for odor perception was determined when the OIC was 4 ou/m3 at the 99th percentile for the odor exposure over time periods of nighttime of summer. The study of dose–response relationship could be useful for the odor management and control of WWTP to maximize the satisfaction of air quality for the residents inside city.


i-Perception ◽  
2021 ◽  
Vol 12 (2) ◽  
pp. 204166952110095
Author(s):  
Elmeri Syrjänen ◽  
Håkan Fischer ◽  
Marco Tullio Liuzza ◽  
Torun Lindholm ◽  
Jonas K. Olofsson

How do valenced odors affect the perception and evaluation of facial expressions? We reviewed 25 studies published from 1989 to 2020 on cross-modal behavioral effects of odors on the perception of faces. The results indicate that odors may influence facial evaluations and classifications in several ways. Faces are rated as more arousing during simultaneous odor exposure, and the rated valence of faces is affected in the direction of the odor valence. For facial classification tasks, in general, valenced odors, whether pleasant or unpleasant, decrease facial emotion classification speed. The evidence for valence congruency effects was inconsistent. Some studies found that exposure to a valenced odor facilitates the processing of a similarly valenced facial expression. The results for facial evaluation were mirrored in classical conditioning studies, as faces conditioned with valenced odors were rated in the direction of the odor valence. However, the evidence of odor effects was inconsistent when the task was to classify faces. Furthermore, using a z-curve analysis, we found clear evidence for publication bias. Our recommendations for future research include greater consideration of individual differences in sensation and cognition, individual differences (e.g., differences in odor sensitivity related to age, gender, or culture), establishing standardized experimental assessments and stimuli, larger study samples, and embracing open research practices.


2006 ◽  
Vol 69 (4) ◽  
pp. 743-748 ◽  
Author(s):  
WONDWOSSEN A. GEBREYES ◽  
SIDDHARTHA THAKUR ◽  
W. E. MORGAN MORROW

Conventional swine production evolved to routinely use antimicrobials, and common occurrence of antimicrobial-resistant Salmonella has been reported. There is a paucity of information on the antimicrobial resistance of Salmonella in swine production in the absence of antimicrobial selective pressure. Therefore, we compared the prevalence and antimicrobial resistance of Salmonella isolated from antimicrobial-free and conventional production systems. A total of 889 pigs and 743 carcasses were sampled in the study. Salmonella prevalence was significantly higher among the antimicrobial-free systems (15.2%) than the conventional systems (4.2%) (odds ratio [OR] = 4.23; P < 0.05). Antimicrobial resistance was detected against 10 of the 12 antimicrobials tested. The highest frequency of resistance was found against tetracycline (80%), followed by streptomycin (43.4%) and sulfamethoxazole (36%). Frequency of resistance to most classes of antimicrobials (except tetracycline) was significantly higher among conventional farms than antimicrobial-free farms, with ORs ranging from 2.84 for chloramphenicol to 23.22 for kanamycin at the on-farm level. A total of 28 antimicrobial resistance patterns were detected. A resistance pattern with streptomycin, sulfamethoxazole, and tetracycline (n = 130) was the most common multidrug resistance pattern. There was no significant difference in the proportion of isolates with this pattern between the conventional (19.5%) and the antimicrobial-free systems (18%) (OR = 1.8; P > 0.05). A pentaresistance pattern with ampicillin, chloramphenicol, streptomycin, sulfamethoxazole, and tetracycline was strongly associated with antimicrobial-free groups (OR = 5.4; P = 0.01). While showing the higher likelihood of finding antimicrobial resistance among conventional herds, this study also implies that specific multidrug-resistant strains may occur on antimicrobial-free farms. A longitudinal study with a representative sample size is needed to reach more conclusive results of the associations detected in this study.


2005 ◽  
Vol 68 (2) ◽  
pp. 135-144 ◽  
Author(s):  
Hugo Medeiros Garrido de Paula ◽  
Amauri Gouveia ◽  
Marcos Vinícius de Almeida ◽  
Katsumasa Hoshino

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