Primary Bone Tumor of the Spine

OrthoMedia ◽  
2021 ◽  
Keyword(s):  
Bone Tumor ◽  
Primary Bone Tumor ◽  
Primary Bone

scholarly journals Exposure of primary bone tumor-associated stromal cells to multi-pesticides at low doses and paracrine effects on osteoclast differentiation

Bone Reports ◽  
2020 ◽  
Vol 13 ◽  
pp. 100421
Author(s):  
Valérie Trichet ◽  
Louis-Romée Le Nail ◽  
Régis Brion ◽  
Françoise Rédini ◽  
François Vallette ◽  
...  
Keyword(s):  
Bone Tumor ◽  
Stromal Cells ◽  
Osteoclast Differentiation ◽  
Low Doses ◽  
Paracrine Effects ◽  
Primary Bone Tumor ◽  
Primary Bone

An Uncommon Presentation of a Primary Bone Tumor

2018 ◽  
Vol 40 (7) ◽  
pp. 555-557
Author(s):  
Daniel Koh ◽  
Theodore Lau ◽  
Evonne Teoh ◽  
Kenneth K. Lau
Keyword(s):  
Bone Tumor ◽  
Primary Bone Tumor ◽  
Uncommon Presentation ◽  
Primary Bone

scholarly journals Macrophages in Osteosarcoma Immune Microenvironment: Implications for Immunotherapy

2020 ◽  
Vol 10 ◽  
Author(s):  
Zhong-Wei Luo ◽  
Pan-Pan Liu ◽  
Zhen-Xing Wang ◽  
Chun-Yuan Chen ◽  
Hui Xie
Keyword(s):  
Overall Survival ◽  
Tumor Microenvironment ◽  
Bone Tumor ◽  
Immune Cells ◽  
Therapeutic Approaches ◽  
Immune Microenvironment ◽  
Primary Bone Tumor ◽  
Promising Strategy ◽  
Primary Bone ◽  
Malignant Primary Bone Tumor

Osteosarcoma is a malignant primary bone tumor commonly occurring in children and adolescents. The treatment of local osteosarcoma is mainly based on surgical resection and chemotherapy, whereas the improvement of overall survival remains stagnant, especially in recurrent or metastatic cases. Tumor microenvironment (TME) is closely related to the occurrence and development of tumors, and macrophages are among the most abundant immune cells in the TME. Due to their vital roles in tumor progression, macrophages have gained increasing attention as the new target of tumor immunotherapy. In this review, we present a brief overview of macrophages in the TME and highlight the clinical significance of macrophages and their roles in the initiation and progression of osteosarcoma. Finally, we summarize the therapeutic approaches targeting macrophage, which represent a promising strategy in osteosarcoma therapies.

scholarly journals An unusual presentation of pediatric osteoblastoma in a patient with Klippel-Trenaunay-Weber syndrome: case report

2015 ◽  
Vol 15 (6) ◽  
pp. 638-640 ◽  
Author(s):  
Scott A. Wallace ◽  
Romeo C. Ignacio ◽  
Arnett Klugh ◽  
Gregory Gates ◽  
Marion C. W. Henry
Keyword(s):  
Case Report ◽  
Bone Tumor ◽  
Unusual Presentation ◽  
Long Bone ◽  
Primary Bone Tumor ◽  
Rare Syndrome ◽  
Weber Syndrome ◽  
Primary Bone

Osteoblastoma is an uncommon primary bone tumor that usually presents as a painful lesion in a long bone or in the spine. Osteoblastoma has been reported only twice in the literature in conjunction with systemic fibromatosis. The authors report the case of an 8-year-old girl with suspected Klippel-Trenaunay-Weber syndrome, a rare syndrome of systemic fibromatosis, who presented with a painless thoracic rib lesion that was found to be an osteoblastoma.

TNF-Related Apoptosis Inducing Ligand (TRAIL) inhibits primary bone tumor growth and augments survival in a human model ewing sarcoma

Bone ◽  
2008 ◽  
Vol 42 ◽  
pp. S94
Author(s):  
Loic Geffroy ◽  
Damien Chauviere ◽  
Francois Lamoureux ◽  
Gaelle Picarda ◽  
Olivier Delattre ◽  
...  
Keyword(s):  
Tumor Growth ◽  
Bone Tumor ◽  
Ewing Sarcoma ◽  
Human Model ◽  
Primary Bone Tumor ◽  
Primary Bone

Soft tissue hemangioma with adjacent periosteal reaction simulating a primary bone tumor

1996 ◽  
Vol 25 (2) ◽  
pp. 174-177 ◽  
Author(s):  
John L. DeFilippo ◽  
J. S. Yu ◽  
Lawrence Weis ◽  
Joel Lucas
Keyword(s):  
Soft Tissue ◽  
Bone Tumor ◽  
Periosteal Reaction ◽  
Primary Bone Tumor ◽  
Primary Bone

scholarly journals Demographic, clinico-pathological features and management pattern of primary bone tumors in a tertiary care hospital of South India

2021 ◽  
Vol 8 (1) ◽  
pp. 60
Author(s):  
Subbiah Shanmugam ◽  
Sujay Susikar ◽  
Bharanidharan T. ◽  
Arun Victor Jebasingh
Keyword(s):  
Bone Tumor ◽  
Bone Tumors ◽  
Tertiary Care ◽  
Tumor Location ◽  
Care Hospital ◽  
Pathological Features ◽  
Primary Bone Tumor ◽  
Primary Bone Tumors ◽  
True Incidence ◽  
Primary Bone

<p><strong>Background</strong>: Primary bone tumors are very rare tumors. The true incidence of bone tumors is not well established and is under reported due to rarity and lack of accurate registries. Hence it is essential to study about the demographic, clinico-pathological features and the pattern of surgical management of bone tumors. The aim of this study is to analyze the demographic and clinico-pathological features of primary bone tumors that were managed by surgery.</p><p><strong>Methods</strong>: A retrospective analysis of all patients with primary bone tumor who were treated by surgery from 2012 to 2019 was done. The age, sex distribution, histopathology, location of the tumor and surgical procedure done were analyzed.</p><p><strong>Results</strong>: Among 103 patients analyzed, 66 (64%) were men and 37 (36%) were women. Primary bone tumors most commonly presented in 11 to 20 years of age with 35 (33.9%) patients occurring in this age group. Osteosarcoma was the most common primary bone tumor and it occurred in 49 (47.6%) patients, out of which 34 (69.3%) patients were below 20 years of age. Giant cell tumor was the most common benign bone tumor and it occurred in 22 patients, out of which nine (40.9%) patients were of age 21 to 30 years. Distal femur was the most common site with 39 (37.9%) patients. The limb preservation rate for malignant appendicular bone tumors was 69.0%.</p><p><strong>Conclusions</strong>: The diagnosis of bone tumor depends not only on histopathological features but also needs correlation with age, clinical features, tumor location and radiological features for confirmation of diagnosis.</p>

Sign in / Sign up

Export Citation Format

Share Document