The Potential of Medicinal Plants as Galactagogue in Indonesia: A Review from Medical Perspective

2021 ◽  
Vol 14 (3) ◽  
pp. 1595-1612
Author(s):  
Astrid Feinisa Khairani ◽  
Teuku Muhammad Adzdzikri ◽  
Shafa Tasya Menggala ◽  
Muhammad Hasan Bashari ◽  
Enny Rohmawaty ◽  
...  
Keyword(s):  
Clinical Trials ◽  
Breast Milk ◽  
Medicinal Plants ◽  
Literature Review ◽  
Common Factor ◽  
World Health ◽  
Efficacy And Safety ◽  
Positive Effects ◽  
The World ◽  
Medical Perspective

The World Health Assembly's target in exclusive breastfeeding has not been achieved. The most common factor contributing to this problem is the perceived insufficient production of breast milk, leading to the inability to give breastmilk to her child. Milk production can be increased using some ways, such as herbal galactagogue. This article aimed to review the effectiveness of some medicinal plants as galactagogues. This study uses a literature review approach by using several sources selected based on the criteria that have been set by researchers. Based on thirteen literature, herbs reviewed in this article showed positive effects as a galactagogue. Evidence regarding its efficacy and safety is scarce. Additionally, few clinical trials exist to justify its effectiveness. Further clinical trials are needed to support these findings.

scholarly journals The efficacy and safety of interferons for the treatment of patients with COVID-19: protocol for systematic review and meta-analysis of controlled trials

2021 ◽  
Author(s):  
Afsaneh Noormandi ◽  
Mohammad Fathalipour ◽  
Reza Daryabeygi-Khotbehsara ◽  
Soheil Hassanipour
Keyword(s):  
Systematic Review ◽  
Clinical Trials ◽  
Meta Analysis ◽  
World Health ◽  
Controlled Trials ◽  
Efficacy And Safety ◽  
Global Pandemic ◽  
The World ◽  
Health Organization ◽  
Time Of Administration

Background and objective: COVID-19 has since been declared a global pandemic by the World Health Organization (WHO), infecting millions worldwide. The use of Interferon (INF) subtypes previously examined in the treatment of SARS and MERS is also being initiated in some clinical trials. Although different clinical trials were evaluated IFNs in the treatment of COVID-19, their efficacy and safety remain unknown. Therefore, this study aims to systematically assess IFNs efficacy and safety in treating patients with COVID-19. Methods: The protocol has been registered in the PROSPERO International Prospective Register (CRD42020200643) on 24 July 2020. This protocol has been arranged according to the PRISMA-P (Preferred Reporting Items for Systematic Review and Meta-Analysis Protocols) 2015 checklist. Discussion: Due to lack of approved medication for the covid-19 treatment and also various mutations of this virus, evaluated the efficacy and safety of medications by various studies could help for finding treatments with high effectiveness. IFNs are one of the medications that have been administered in covid-19 infection.  Moreover, the best time of administration and dose of this medication was unknown. Although meta-analysis is a potent source for assessing the accuracy of subjects, heterogeneity of articles is a potent limitation of our work.

scholarly journals SARS-CoV-2 infection and some controversies concerning therapy with chloroquine and hydroksychloroquine: case report and selected literature review

2020 ◽  
Vol 74 ◽  
pp. 348-353
Author(s):  
Hubert Ciepłucha ◽  
Brygida Knysz
Keyword(s):  
Case Report ◽  
Literature Review ◽  
Infected Patient ◽  
World Health ◽  
Efficacy And Safety ◽  
X Ray ◽  
Persistent Symptoms ◽  
The World ◽  
Chest X Ray ◽  
Health Organization

Covid-19 is caused by a new virus and no effective therapy is available. The following article presents the case of a 47-year-old woman with SARS-CoV-2 infection. The infection was initially mild but because of exacerbation of the symptoms: cough, fever, headache, extreme weakness she was admitted to the hospital. The chest X-ray revealed pneumonia due to Covid-19, that is why CT was not done. Due to persistent symptoms of infection, therapy containing chloroquine and azithromycin was introduced, obtaining a very quick improvement in the condition of the infected patient. Because of ambiguous opinions of the efficacy of these two drugs in the therapy of SARS-CoV-2 infection, the authors wonder whether the improvement was either a result of the treatment with chloroquine and azithromycin or because of the natural Covid-19 course. The following part of the article briefly reviews research and world reports as well as problems connected with chloroquine and hydroxychloroquine therapy in patients with Covid-19. The current positions of the World Health Organization (WHO) and the Food and Drug Administration (FDA) in terms of the topic were also presented. It was also pointed out the way unprecedented before the therapy has been introduced based on several and variable report about the efficacy and safety of these drugs.

Natural products from the traditional Moroccan pharmacopoeia: A potential lead for the prevention and treatment of COVID-19

2020 ◽  
Vol 11 (SPL1) ◽  
pp. 1278-1285
Author(s):  
Mohamed Yafout ◽  
Amine Ousaid ◽  
Ibrahim Sbai El Otmani ◽  
Youssef Khayati ◽  
Amal Ait Haj Said
Keyword(s):  
Medicinal Plants ◽  
Plant Extracts ◽  
Molecular Mechanisms ◽  
Scientific Literature ◽  
Treatment Protocol ◽  
World Health ◽  
The World ◽  
Health Organization ◽  
Promising Source

The new SARS-CoV-2 belonging to the coronaviruses family has caused a pandemic affecting millions of people around the world. This pandemic has been declared by the World Health Organization as an international public health emergency. Although several clinical trials involving a large number of drugs are currently underway, no treatment protocol for COVID-19 has been officially approved so far. Here we demonstrate through a search in the scientific literature that the traditional Moroccan pharmacopoeia, which includes more than 500 medicinal plants, is a fascinating and promising source for the research of natural molecules active against SARS-CoV-2. Multiple in-silico and in-vitro studies showed that some of the medicinal plants used by Moroccans for centuries possess inhibitory activity against SARS-CoV or SARS-CoV-2. These inhibitory activities are achieved through the different molecular mechanisms of virus penetration and replication, or indirectly through stimulation of immunity. Thus, the potential of plants, plant extracts and molecules derived from plants that are traditionally used in Morocco and have activity against SARS-CoV-2, could be explored in the search for a preventive or curative treatment against COVID-19. Furthermore, safe plants or plant extracts that are proven to stimulate immunity could be officially recommended by governments as nutritional supplements.

scholarly journals Literature Review The Relationship Of Antenatal Class Towards Mothers’ Knowledge Of DangerousSign During Pregnancy

2021 ◽  
Vol 3 (2) ◽  
Author(s):  
Ayu Kurniati ◽  
Enny Fitriahadi
Keyword(s):  
Developing Countries ◽  
Mortality Rate ◽  
Literature Review ◽  
World Health ◽  
Live Births ◽  
Complication Risk ◽  
The World ◽  
Health Organization ◽  
Relationship Of ◽  
The Relationship

IN 2013, the World Health Organization, released data in the form of Maternal Mortality Rate (MMR) worldwide, and the number reached 289,000 per 100, 000 live births, which 99% of cases occurred in developing countries. Research aims to discover the relationship of antenatal class towards mothers’ knowledge of the dangerous sign during pregnancy. The result showed that there is a relationship of antenatal class towards mothers’ knowledge of dangerous sign during pregnancy, From this result, the researcher concludes that antenatal class could increase mothers’ knowledge of dangerous sign during pregnancy and may decrease the complication risk during the childbirth.

scholarly journals Access barriers to visual health

2018 ◽  
Vol 16 (1) ◽  
pp. 95-109 ◽  
Author(s):  
María Alejandra Rodríguez-Echeverría ◽  
Angélica María Páez-Castro
Keyword(s):  
Health Care ◽  
Literature Review ◽  
Health Care System ◽  
World Health ◽  
Local Health Authority ◽  
Barriers To Access ◽  
The World ◽  
Health Organization ◽  
Visual Health ◽  
Care System

A number of factors and conditions hinder and restrict access to the health care system and its different services; these barriers to access put at risk the health of people by affecting adequate processes. Objective: To carry out a literature review on barriers to access to the health care system and visual health services in Colombia and around the world. Methodology: A literature review was carried out based on a search of the Medline, ScienceDirect, and Pubmed databases, as well as indexed public health journals and the websites of the Local Health Authority, the World Health Organization, the Pan American Health Organization, the UNESCO, and the Brien Holden Vision Institute. Results: The main barriers related to demand, both in general services and in visual health, are the lack of perception on the need for service and lack of economic resources; at the offer level, the existing policies constitute a real obstacle. Conclusions: Awareness-raising in the population, together with the implementation of health policies that grant equal access to health care services, are fundamental to prevent people from being affected, to a large extent, by barriers related to demand or offer, regardless of their location or level of income.

Bioactive Natural Medicinal Plants in South Indian Western Ghats and Their Pharmacological Importance

2020 ◽  
Vol 6 (2) ◽  
pp. 62-69
Author(s):  
M. Tamizharasi ◽  
R. Rajila ◽  
D. Beula Shiny ◽  
J. Vijila Jasmin ◽  
T. Kumaran
Keyword(s):  
Medicinal Plants ◽  
Western Ghats ◽  
New Drugs ◽  
World Health ◽  
Plant Resources ◽  
Medical Products ◽  
Primary Health ◽  
South Indian ◽  
The World ◽  
Health Organization

Awareness of traditional knowledge and medicinal plants can play a key role in the utilization and discovery of natural plant resources. Plants became the basis of medicine system throughout the world for thousands of years and continue to provide mankind with new remedies. Researchers generally agree that natural products from plants and other organisms have been the most consistently successful source for ideas for new drugs. The world health organization estimates that 80% of the population living in the developing countries relies exclusively on traditional medicine for their primary health care. More than half of the world's population still relies entirely on plants for medicines, and plants supply the active ingredients of most traditional medical products. The review shows the south Indian medicinal plant products has been used by people to treat various health ailments.

Biochemic System of Medicine

2019 ◽  
pp. 403-431
Author(s):  
Srijan Goswami ◽  
Sagarika Mitra ◽  
Piyasee Paul ◽  
Dipjyoti Dey ◽  
Sankalan Das
Keyword(s):  
Literature Review ◽  
World Health Organization ◽  
Complementary Therapies ◽  
World Health ◽  
Nutrition Science ◽  
The World ◽  
History And Literature ◽  
Health Organization

The biochemic system of medicine, also known as the inorganic cell salt therapy, pioneered by Dr. Wilhelm Heinrich Schuessler, following the footsteps of Dr. Samuel Hahnemann, is the oldest form of nutraceutical therapy approved and recognized by the World Health Organization as one of the complementary therapies. The chapter presents the fundamental ideology and concepts that underlies the promising system of biochemic medicine as concisely, simply, and to-the-point as possible. The chapter begins with a brief introduction to biochemic system, nutrition science, and concepts of nutraceuticals, followed by a brief history and literature review. It covers biochemic system of medicine and its relevant concepts before closing the chapter with a conclusion.

scholarly journals The impact of inclusion, dose and duration of pyrazinamide (PZA) on efficacy and safety outcomes in tuberculosis: systematic review and meta-analysis protocol

2019 ◽  
Vol 8 (1) ◽  
Author(s):  
James D. Millard ◽  
Elizabeth A. Mackay ◽  
Laura J. Bonnett ◽  
Geraint R. Davies
Keyword(s):  
Systematic Review ◽  
Clinical Trials ◽  
Meta Analysis ◽  
World Health ◽  
Controlled Trials ◽  
Cochrane Central Register ◽  
Efficacy And Safety ◽  
Safety Outcomes ◽  
Meta Regression ◽  
Indirect Comparisons

Abstract Background Pyrazinamide (PZA) is a key component of current and future regimens for tuberculosis (TB). Inclusion of PZA at higher doses and for longer durations may improve efficacy outcomes but must be balanced against the potential for worse safety outcomes. Methods We will search for randomised and quasi-randomised clinical trials in adult participants with and without the inclusion of PZA in TB treatment regimens in the Cochrane infectious diseases group’s trials register, Cochrane central register of controlled trials (CENTRAL), MEDLINE, EMBASE, LILACS, the metaRegister of Controlled Trials (mRCT) and the World Health Organization (WHO) international clinical trials registry platform. One author will screen abstracts and remove ineligible studies (10% of which will be double-screened by a second author). Two authors will review full texts for inclusion. Safety and efficacy data will be extracted to pre-piloted forms by one author (10% of which will be double-extracted by a second author). The Cochrane risk of bias tool will be used to assess study quality. The study has three objectives: the association of (1) inclusion, (2) dose and (3) duration of PZA with efficacy and safety outcomes. Risk ratios as relative measures of effect for direct comparisons within trials (all objectives) and proportions as absolute measures of effect for indirect comparisons across trials (for objectives 2 and 3) will be calculated. If there is insufficient data for direct comparisons within trials for objective 1, indirect comparisons between trials will be performed. Measures of effect will be pooled, with corresponding 95% confidence intervals and p values. Meta-analysis will be performed using the generalised inverse variance method for fixed effects models (FEM) or the DerSimonian-Laird method for random effects models (REM). For indirect comparisons, meta-regression for absolute measures against dose and duration data will be performed. Heterogeneity will be quantified through the I2-statistic for direct comparisons and the τ2 statistic for indirect comparisons using meta-regression. Discussion The current use of PZA for TB is based on over 60 years of clinical trial data, but this has never been synthesised to guide rationale use in future regimens and clinical trials. Systematic review registration: International Prospective Register of Systematic Reviews (PROSPERO) CRD42019138735

scholarly journals Acupuncture for Treatment of Autism Spectrum Disorders

2012 ◽  
Vol 2012 ◽  
pp. 1-10 ◽  
Author(s):  
Xue Ming ◽  
Xiang Chen ◽  
Xiao T. Wang ◽  
Zhen Zhang ◽  
Victor Kang ◽  
...  
Keyword(s):  
Clinical Trials ◽  
Autism Spectrum Disorders ◽  
Literature Review ◽  
Acupuncture Treatment ◽  
Children With Autism ◽  
Autism Spectrum ◽  
Experimental Designs ◽  
Efficacy And Safety ◽  
Spectrum Disorders ◽  
Double Blinded

Background. There has been lack of reviews of evidence on efficacy, methodology, and/or safety of acupuncture in autism spectrum disorders. This paper examines the emerging evidence of the effects of acupuncture in the treatment of autistic children.Method. A literature review was completed via Medline and three Chinese search engines. A total of 31 studies were evaluated for acupuncture methodology, study design, treatment effects, and tolerability.Results. The acupoints used, the duration of needling, the frequency of treatment, the choice of stimulation, and the course of the treatment were highly variable amongst the studies. Behavioral and/or developmental improvements were reported in all acupuncture treatment studies. All studies reported general tolerability. Weakness of experimental designs was discussed.Conclusions. Vigorously controlled double-blinded clinical trials are needed to evaluate the efficacy and safety of acupuncture in children with autism spectrum disorders.

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