scholarly journals Effectiveness Study of Typical and Atypical Antipsychotics on Patients with Schizophrenia using WHO Disability Assessment Schedule (WHODAS 2.0)

2021 ◽  
Vol 14 (3) ◽  
pp. 1143-1148
Author(s):  
Ratna Agrawal ◽  
Bhabagrahi Rath
Keyword(s):  
Social Life ◽  
Atypical Antipsychotics ◽  
Mental Disability ◽  
Medical Sciences ◽  
Whodas 2.0 ◽  
Significant Difference ◽  
Significant Disability ◽  
Study Participants ◽  
Typical And Atypical Antipsychotics ◽  
Typical Antipsychotics

Background and Objectives: Schizophrenia is the commonest and one of the best known mental disorder which usually starts before 25 years of age, leading to significant disability in both behavioural and social life. Usually the person with any mental disability has to face social ignorance, this further leads to deterioration of their health and productivity. The deterioration of the health is not only due to the course of the disease but also may be due to treatment by some of the antipsychotics, which are the main drugs for the schizophrenia management. So, the present study has been designed to determine the effectiveness of typical and atypical antipsychotics in patients with schizophrenia in terms of disability reduction caused by them using WHODAS 2.0. Methods: After taking ethics committee approval and informed consent from study participants this prospective, observational, questionnaire based study has been conducted in the Department of Psychiatry and Pharmacology of V. S.S. Institute of Medical Sciences and Research, Burla, Odisha using WHODAS 2.0 in patients suffering from schizophrenia. Results: Atypical antipsychotics lead to more reduction in disability in patients with schizophrenia than typical antipsychotics both at 6 and 12 month duration. On comparing the various atypical antipsychotics used in the study, there was no significant difference among them. Conclusion: Based on the above findings, it can be concluded that atypical antipsychotics are more effective than typical antipsychotics in terms of disability reduction. The findings may help clinicians to get better insight in the management of schizophrenia.

scholarly journals Psychopharmacotherapy and Remission of Patients with Schizophrenia

2009 ◽  
Vol 24 (S1) ◽  
pp. 1-1
Author(s):  
D. Degmecic ◽  
I. Pozgain ◽  
P. Filakovic ◽  
K. Dodig-Curkovic
Keyword(s):  
Atypical Antipsychotics ◽  
Psychiatric Treatment ◽  
Services Research ◽  
Sociodemographic Data ◽  
Significant Difference ◽  
Remission Criteria ◽  
University Department ◽  
Number Of Visits ◽  
The University ◽  
Typical Antipsychotics

Aim of our study was to determine which antipsychotic are used in the treatment of patients with schizophrenia, as well as to assess are there differences between patients treated with typical and atypical antipsychotics and how many of them are in remission according to the defined remission criteria.All outtreated patients with schizophrenia treated at the University Department of Psychiatry Osijek in the period of three months were assessed. the patients were divided in two groups, one group of patients treated with typical antipsychotics, and the other group treated with atipycal antipsychotics. All of them were assessed with specially designed questionnaire about sociodemographic data, than with 8 item of PANSS (remission criteria), and with Clinical Global Impression scale. the authors analysed 193 patients with schizophrenia, 65 (33.7%) of them were treated with typical antipsychotics, and 128 (66.3%) patients were treated with atypical antipsychotics. Our results suggest that there is statisticaly significant difference in the duration of psychiatric treatment between those two groups of patients as well as statistically significant difference in the number of visits to the psychiatrist in the last two years. Only item from the PANSS remision criteria in which we observed statistically significant difference between two groups of patients was G 9 (Unusal thought content). in our group of patients 98 of them (50.8%) were in remission according to the PANSS remission criteria.Conclusion:The introduction of standardized remission criteria may offer significant opportunities for clinical practice, health services research and clinical trials.

scholarly journals Prevalence of nomophobia among the undergraduate medical students of Mandya Institute of Medical Sciences, Mandya

2018 ◽  
Vol 5 (12) ◽  
pp. 5455 ◽  
Author(s):  
Harish B. R. ◽  
Bharath J.
Keyword(s):  
Undergraduate Students ◽  
Mobile Phones ◽  
Cross Sectional Study ◽  
Medical Sciences ◽  
Undergraduate Medical Students ◽  
Cross Sectional ◽  
Significant Difference ◽  
Study Population ◽  
And Gender ◽  
Study Participants

Background: Nomophobia (no mobile phobia), is the fear an individual gets if he is out of mobile phone contact due to no network, has run out of balance or run out of battery; the persons gets anxious, which adversely affects the concentration level of the person. Since the younger generation is the latest consumer of the mobile phones and the under 25 year age group in professional colleges like medical colleges use mobile phones quite frequently this study was conducted to determine the prevalence of nomophobia in the undergraduate students of Mandya Institute of Medical Sciences, Mandya.Methods: This was a cross sectional study conducted at Mandya Institute of Medical Sciences during May 2018 to June 2018. All undergraduate students were included i.e. same as study population (n=450). Data collection was done during June 2018 using structured questionnaire.Results: Mean age of the study participants was 20.1±1.3 years. Majority of the study population were hostelites. Approximate amount of money spent on last recharge/last postpaid bill was INR 354.1±185.0. Main reasons for using smartphones were ‘to call family members’, ‘using internet for academics’ and ‘for social networking’. Prevalence of moderate to severe nomophobia among the study population was 99.0%. No statistical significant difference was observed between gender and nomophobia.Conclusions: Prevalence of nomophobia among undergraduate medical student was 99.0% and majority had moderate level of nomophobia. There was no association between nomophobia and gender, place of present residence, amount of money spent on last recharge. 

Medication-precipitated Seizure in Psychiatric Patients: Typical vs. Atypical Antipsychotics

2020 ◽  
Vol 9 (3) ◽  
pp. 228-233
Author(s):  
Saeed S. Shafti
Keyword(s):  
Atypical Antipsychotics ◽  
First Generation ◽  
Psychiatric Patients ◽  
Quantitative Difference ◽  
Psychiatric Hospitals ◽  
Symptomatic Management ◽  
Significant Difference ◽  
Inpatient Management ◽  
Seizure Attacks ◽  
Typical Antipsychotics

Backgrounds: It is unknown whether second-generation antipsychotics are safer than first-generation antipsychotics in terms of seizure induction. Objective: In the present assessment, the relationships between the incidence of seizure attacks among a great sample of non-western psychiatric inpatients and prescribed typical and atypical antipsychotics have been probed and analyzed based on the existing data in the literature. Methods: Razi psychiatric hospital, as one of the largest and oldest public psychiatric hospitals in the Middle East, had been selected as the field of study in the present retrospective estimation. For assessment, all inpatients that had suffered a seizure during the last sixtyfour months had been included in the current study. Results: Among seventy-four patients who had experienced seizure attack during the inpatient management, and had been prescribed antipsychotics for symptomatic management of primary psychiatric disorders, 67.56% had received atypical antipsychotic and the remaining (32.43%) had received typical antipsychotics, which revealed a significant quantitative difference between them (p<0.000). Among atypical antipsychotics, olanzapine was the most recommended antipsychotic (33.78%), followed by risperidone (34%), quetiapine (9.45%), and clozapine (n=1, 1.35%). Among typical antipsychotics, too, haloperidol (28.37%) was significantly more prescribed than chlorpromazine (2.70%) and thioridazine (1.35%) (p<0.000). By the way, there was no significant difference, quantitatively, between olanzapine and haloperidol in the present evaluation (p<0.47). Conclusion: Atypical antipsychotics have comparable potentiality, as typical antipsychotics, for triggering seizure attacks, which demands indispensable cautiousness by clinicians when prescribing such a group of medications for epileptic and neuropsychiatric patients.

scholarly journals Evaluation of Students’ Awareness of Charter of Patients' Rights

2019 ◽  
Vol 5 (4) ◽  
pp. 269-276
Author(s):  
Hadis Ashrafizadeh ◽  
◽  
Mahmood Maniati ◽  
Mohammad Adineh ◽  
Nasrin Elahi ◽  
...  
Keyword(s):  
Human Society ◽  
Human Beings ◽  
Medical Sciences ◽  
Test Analysis ◽  
Patients Rights ◽  
Study Results ◽  
Significant Difference ◽  
The University ◽  
Study Participants ◽  
Awareness Level

Background: As an essential principle, the collective life of human beings can constitute a human society only when human rights are respected. Demanding and respecting the rights of patients, as an inevitable part of human society, requires familiarity with patient-involved individuals. The present study aimed to determine the awareness level of Ahvaz Jundishapur University of Medical Sciences (AJUMS) students about the Charter of Patients’ Rights (CPR). Methods: This descriptive-analytical study was conducted on 200 senior university students who had been in contact with patients during their undergraduate program. They were invited from different faculties of the university. The data collection tool was a two-section questionnaire. The first section covered the demographic information, and the second included 29 questions about the 5 principles of the CPR. The obtained data were analyzed in SPSS by descriptive statistics, and analytical tests, including Independent Samples t-test, Analysis of Variance (ANOVA), and Spearman’s correlation coefficient. Results: From the 200 study participants, 103 (51%) were female. The Mean±SD of students’ awareness was 14.50±2.3. The highest and lowest mean scores belonged to the areas of access to services and confidentiality. There was no statistically significant difference between the awareness score of students from different faculties (P=0.359). Conclusion: This study results suggested that the awareness level of the medical students about the CPR was unsatisfactory. Instituting ethical codes among students and providing them knowledge of their professional lives is an essential part of the university’s responsibilities.

scholarly journals Registry-Based Incidence of Multiple Sclerosis in Southwestern Iran, 2001-2014

2017 ◽  
Vol 42 (1) ◽  
pp. 08-13
Author(s):  
Mohammad Khammarnia ◽  
Aziz Kassani ◽  
Elham Izadi ◽  
Fatemeh Setoodehzadeh
Keyword(s):  
Multiple Sclerosis ◽  
Age Group ◽  
Newly Diagnosed ◽  
Medical Sciences ◽  
Significant Difference ◽  
The Mean ◽  
Receive Treatment ◽  
Southwestern Iran ◽  
Study Participants ◽  
To Receive

Multiple Sclerosis (MS) is the most common cause of neurological disability in young adults. It is estimated that more than two million people have MS worldwide. This study aimed to assess the incidence of MS and its associated factors in Shiraz, Southwestern Iran. Data related to the inci-dence of MS were obtained from the MS center of Shiraz University of Medical Sciences from 2001 to 2014. The study participants were all residents of Shiraz. The subjects were diagnosed with MS by neurologists (all newly diagnosed patients from 2001-2014) and were registered in MS center to receive treatment. Descriptive statistics and univariate and multivariate Poisson re-gression analysis were done. During the study period, 2637 eligible patients were identified. The highest incidence of MS occurred in 2011 and 2012 (17.62, 95% CI: 8.02-38.72 and 16.92, 95% CI: 6.23-45.88 per 100,000 respectively). Besides, the female to male ratio was 2.95 and 44.71% of the MS patients (1070 cases) were in the 20-30 years’ age group. In addition, the mean age of the patients was 30.18±8.86 years. The results showed a significant difference among different age and sex groups regarding the incidence of MS (p=0.01). Moreover, a significant relationship was observed between education level and incidence of MS (p=0.03). The incidence of MS has in-creased in the south of Iran more than other regions.

scholarly journals Are all antipsychotic drugs the same?

2011 ◽  
Vol 199 (4) ◽  
pp. 269-271 ◽  
Author(s):  
Stefan Leucht ◽  
John M. Davis
Keyword(s):  
Decision Making ◽  
Side Effects ◽  
Classification System ◽  
Atypical Antipsychotics ◽  
Antipsychotic Drugs ◽  
Mechanisms Of Action ◽  
Decision Making Process ◽  
Shared Decision ◽  
Typical And Atypical Antipsychotics ◽  
Typical Antipsychotics

SummaryThe classification system of atypical and typical antipsychotics has created a lot of confusion and might be abandoned. Nevertheless, to say that all drugs are the same and that therefore it does not matter which drug is given is wrong. Both typical and atypical antipsychotics differ in side-effects, mechanisms of action, cost and efficacy. The available choice of antipsychotics should be adapted to individual patients in a shared decision-making process.

Typical and Atypical Antipsychotics in Acute Mania: Comparison of Effectiveness

2017 ◽  
Vol 41 (S1) ◽  
pp. S207-S208
Author(s):  
C.R. Medici ◽  
L.M. Kai ◽  
S.B. Kristensen ◽  
C. Kirkedal ◽  
S.P.V. Straszek
Keyword(s):  
Atypical Antipsychotics ◽  
Mixed Model ◽  
Hospital Admissions ◽  
University Hospital ◽  
World Health ◽  
Defined Daily Dose ◽  
Retrospective Case ◽  
Case Record ◽  
Typical And Atypical Antipsychotics ◽  
Typical Antipsychotics

IntroductionMania is challenging to treat. Typical antipsychotics may be more efficient compared with atypical antipsychotics, however, with unfavourable side effects.ObjectivesTo help the clinician choose between typical and atypical antipsychotics.AimsTo investigate the correlation between change in severity of mania and the corresponding day to day use of typical and atypical antipsychotics.MethodsThis retrospective case record study included patients admitted with mania (International Classification of Diseases 10th revision code F30, F31.0, F31.1, F31.2 or F31.6) at the Department of Affective Disorders, Aarhus University Hospital, Denmark, between January 2013, and December 2015. The dose of typical and atypical antipsychotics was standardized as defined daily dose according to the World Health Organization's guidelines. The severity of mania was measured daily with the Modified Bech-Rafaelsen Mania Scale (MAS-M), a validated, nurse administered scale (MAS-M). We applied a linear regression in a mixed model approach to compare the Mas-M score over time under the influence of typical and atypical antipsychotics, respectively, adjusted for baseline characteristics.ResultsWe included 43 patients. Patients receiving typical antipsychotics had more recent hospital admissions, a higher dosage antipsychotics and more constraint. The baseline MAS-M score was higher in patients receiving typical antipsychotics. The daily change in MAS-M score was–0.25 for typical antipsychotics and–0.23 for atypical antipsychotics with a difference of 0.02 (95% CI 0.008–0.039).ConclusionsThe rate of improvement of mania may be independent of baseline illness or type of antipsychotic medication. This may be confounded by indication.Disclosure of interestThe authors have not supplied their declaration of competing interest.

scholarly journals The Influence of Antipsychotics on the Quality of Life of Patients with Schizophrenia in a Long-stay Psychiatric Facility

2014 ◽  
Vol 15 (2) ◽  
pp. 89-94
Author(s):  
Aleksandra Petrovic Kitic ◽  
Slobodan Jankovic
Keyword(s):  
Quality Of Life ◽  
Atypical Antipsychotics ◽  
World Health ◽  
Psychiatric Facility ◽  
Related Factors ◽  
Significant Difference ◽  
Health Quality ◽  
Health Quality Of Life ◽  
Typical Antipsychotics

ABSTRACT Introduction: Many factors concomitantly influence the quality of life of patients with schizophrenia in a long-stay psychiatric facility. Th e appropriate selection of antipsychotics and the intensity of their adverse effects exert a significant influence on the quality of life of these patients. Th e aim of this study was to identify the influence of antipsychotic-related factors on the quality of life of patients with schizophrenia. Methods: Th e study included 102 beneficiaries at the Institute for Accommodation of Adults “Male Pčelice” in Kragujevac. Th e patients were interviewed on in one day using the questionnaire issued by the World Health Organization. The specified data were obtained from the health files of the beneficiaries. We performed a comparison between patients receiving only atypical antipsychotics, typical antipsychotics or a combination thereof. Results: Th e patients who were receiving only atypical antipsychotics demonstrated better physical health quality of life scores in comparison to those who received combined antipsychotics (77.14 vs. 68.57; U = 332.0; p = 0.02). A statistically significant difference in the mental health quality of life domain was observed between groups of patients receiving various antipsychotic treatments (31.96 vs. 55.27 vs. 49.46; c2 = 7.02; p = 0.03). Conclusion: Patients in a long-stay psychiatric facility who received atypical antipsychotics demonstrated a better quality of life in comparison to those who received typical antipsychotics, possibly due to the superior safety profile of atypical antipsychotics and a greater feeling of individual contentment.

scholarly journals Perceptions and Opinions towards Cell Phone Use as a Risk Factor of Brain Cancer among University Students in Malaysia

2013 ◽  
Vol 4 (1) ◽  
pp. 1-4
Author(s):  
Redhwan Ahmed Al-Naggar ◽  
Yuri V Bobryshev
Keyword(s):  
University Students ◽  
Mobile Phones ◽  
Brain Cancer ◽  
Cell Phone ◽  
Cell Phones ◽  
Medical Sciences ◽  
Cell Phone Use ◽  
The Past ◽  
Carcinogenic Effects ◽  
Study Participants

The worldwide use of cell phones has rapidly increased over the past decades. With the increasing use of mobile phones, concern has been raised about the possible carcinogenic effects as a result of exposure to radiofrequency electromagnetic fields. The objective of this study was to explore the perceptions and opinions towards brain cancer related to cell phone use among university students in Malaysia. The study revealed that the majority of the study participants believe that there is no relationship between brain cancer and hand phone use.DOI: http://dx.doi.org/10.3126/ajms.v4i1.7808 Asian Journal of Medical Sciences 4(2013) 1-4

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