scholarly journals Assessment of Immediate Loading with Mini-Implant Anchorage in Critical Anchorage Cases Between Stainless Steel Versus Titanium Miniscrew Implants: A Controlled Clinical Trial

2018 ◽  
Vol 11 (2) ◽  
pp. 971-977
Author(s):  
Ashith M. V ◽  
B.K. Shetty ◽  
Yash Shekatkar ◽  
Utkarsh Mangal ◽  
Mithun K
Keyword(s):  
Stainless Steel ◽  
Success Rate ◽  
Titanium Implants ◽  
Controlled Clinical Trial ◽  
Miniscrew Implants ◽  
Mini Implants ◽  
Lower Jaw ◽  
Controlled Clinical Study ◽  
Implant Anchorage

Anchorage in orthodontics is a decisive factor in progress and outcome of a case. With the advent of mini-implants, great advances have been achieved in terms of absolute anchorage. The following article compares the use of stainless steel and titanium implants in a split mouth, controlled clinical study, having direct in vivo comparison. 10 patients were selected for the same and carefully evaluated. The mini-implants were placed in the buccal mucosa, under local anaesthesia, after radiographic safe zone selection. The loading protocol was standardised with low immediate load, followed by incremental load up to 150g. For the study, the cases planned with en-masse retraction of the anteriors into the premolar space were selected for the uniformity in mechanics. The results are discussed with comparative analysis between the two materials and their success rate individually and in relation to upper and lower jaw respectively. In results, a significant success rate has been found with use of titanium implants, with higher implant failure in upper jaw compared to lower jaw.

scholarly journals Comparative Evaluation of Biomechanical Performance of Titanium and Stainless Steel Mini Implants at Different Angulations in Maxilla: A Finite Element Analysis

2019 ◽  
Vol 53 (3) ◽  
pp. 197-205
Author(s):  
Kshitij Hemant Sabley ◽  
Usha Shenoy ◽  
Sujoy Banerjee ◽  
Pankaj Akhare ◽  
Ananya Hazarey ◽  
...  
Keyword(s):  
Stainless Steel ◽  
Computer Aided Design ◽  
Three Dimensional ◽  
Titanium Implant ◽  
Titanium Implants ◽  
Element Analysis ◽  
Mini Implants ◽  
The Difference ◽  
Tractional Forces ◽  
Three Dimensional Models

Objective: To assess and compare the tensions and deformations (stresses and strains) generated after application of two types of forces (traction and torsion) in miniscrews of two different materials (titanium and stainless steel) placed at five different angulations. Materials and Methods: Three-dimensional models of the posterior maxillary area and the mini-implants were constructed using computer-aided design software program (CATIA P3 V5-6 R2015 B26 / 2016; Dassault Systèmes). Titanium and stainless steel materials were used for miniscrews. The area constructed was in between the maxillary second premolar and first molar. The models with mini-implants were inserted at five different angulations (30°, 45°, 60°, 75° and 90°). Torsional and tractional forces were applied on these implants, and the models were solved using ANSYS 10.0. Stress generated in implant and in the cortical and cancellous bones was evaluated and compared at all the five angulations. Results: Stress generated in stainless steel mini-implant during torsional and linear force application was less when compared with titanium mini-implant. Also, stress generated in implants of both materials increased as the angle increased from 30° to 90°. Difference in stress generated by stainless steel implant in the cortical bone for both linear and torsional forces was less when compared with titanium implant, whereas for cancellous bone, the difference was insignificant at all the angles. Conclusion: Irrespective of angles, difference in stress generated in stainless steel implants and titanium implants for both the forces was not significant, and hence, stainless steel implants can be used effectively in a clinical setting.

Does surface anodisation of titanium implants change osseointegration and make their extraction from bone any easier?

2008 ◽  
Vol 21 (03) ◽  
pp. 202-210 ◽  
Author(s):  
J. Langhoff ◽  
J. Mayer ◽  
L. Faber ◽  
S. Kaestner ◽  
G. Guibert ◽  
...  
Keyword(s):  
Stainless Steel ◽  
Titanium Implant ◽  
Titanium Implants ◽  
Implant Surface ◽  
Bone Implant ◽  
High Bone ◽  
Titanium Surfaces ◽  
Anodized Titanium ◽  
Titanium Implant Surface

Summary Objectives: Titanium implants have a tendency for high bone-implant bonding, and, in comparison to stainless steel implants are more difficult to remove. The current study was carried out to evaluate, i) the release strength of three selected anodized titanium surfaces with increased nanohardness and low roughness, and ii) bone-implant bonding in vivo. These modified surfaces were intended to give improved anchorage while facilitating easier removal of temporary implants. Material and methods: The new surfaces were referenced to a stainless steel implant and a standard titanium implant surface (TiMAX™). In a sheep limb model, healing period was 3 months. Bone-implant bonding was evaluated either biomechanically or histologically. Results: The new surface anodized screws demonstrated similar or slightly higher bone-implantcontact (BIC) and torque release forces than the titanium reference. The BIC of the stainless steel implants was significant lower than two of the anodized surfaces (p=0.04), but differences between stainless steel and all titanium implants in torque release forces were not significant (p=0.06). Conclusion: The new anodized titanium surfaces showed good bone-implant bonding despite a smooth surface and increased nanohardness. However, they failed to facilitate implant removal at 3 months.

scholarly journals Stainless steel or titanium mini-implants?

2020 ◽  
Vol 90 (4) ◽  
pp. 587-597 ◽  
Author(s):  
Paulo Mecenas ◽  
Daybelis Gonzalez Espinosa ◽  
Paula Coutinho Cardoso ◽  
David Normando
Keyword(s):  
Clinical Trial ◽  
Stainless Steel ◽  
Success Rate ◽  
Randomized Clinical Trial ◽  
Risk Of Bias ◽  
Current Evidence ◽  
Success Rates ◽  
Level Of Evidence ◽  
Manual Search ◽  
Mini Implants

ABSTRACT Objectives To investigate whether there was a difference in success rates when stainless steel (SS) was compared to titanium mini-implants (MIs) in orthodontic patients. Materials and Methods PubMed, Cochrane, Scopus, Web of Science, Lilacs, Google Scholar, Clinical Trials, and OpenGray were searched without restrictions. A manual search was also performed in the references of the included articles. Studies comparing the success rate between SS and titanium MIs were included. Risk of bias (RoB) was assessed using the ROBINS-I (Risk of Bias in Non-randomized Studies-of Interventions) Tool or RoB 2.0 according to the study design. The level of evidence was assessed through GRADE (Grading of Recommendation, Assessment, Development, and Evaluation). Results Six studies met the eligibility criteria. One study was a randomized clinical trial that evaluated extraalveolar MIs, and nonrandomized trials examined interradicular MIs. The RCT presented a low RoB, two nonrandomized trials presented a moderate risk, and three presented a high risk. The quality of the evidence was high for the randomized clinical trial and moderate for the nonrandomized trials. Most studies found no difference between materials, with good success rates for both (SS, 74.6%–100%; titanium: 80.9%–100%) and only one study, with a high RoB, showed a higher success rate with titanium MIs (90%) when compared with SS (50%). A quantitative analysis was not because of the great heterogeneity among the studies. Conclusions Although limited, the current evidence seems to show that the material used is not a major factor in the success rate of MIs. Because it has a lower cost than titanium and presents similar clinical efficiency, SS is a great material for orthodontic MIs.

Sequential Bone Response to Immediately Loaded Mini-Implants, in vivo Study

2006 ◽  
Vol 925 ◽  
Author(s):  
Glaucio Serra Guimarães ◽  
Liliane Siqueira de Morais ◽  
Carlos Nelson Elias ◽  
Marc Andre Meyers
Keyword(s):  
Dental Implants ◽  
Titanium Implants ◽  
Test Material ◽  
Removal Torque ◽  
Bone Implant ◽  
Subcutaneous Injections ◽  
Mini Implants ◽  
Bone Response ◽  
The Right

ABSTRACTThe use of osseointegrated titanium implants has been related like an excellent alternative to traditional orthodontic anchorage methodologies, and they are a necessity when dental elements lack quantity or quality, when extraoral devices are impractical, or when noncompliance during treatment is likely. In orthodontics, the implants can be use to anchor different movements. However, conventional dental implants can only be placed in limited areas such as the retromolar or the edentulous areas. Another limitation has been the direction of the force application and conventional dental implants are troublesome for patients because of the severity of the surgery, the discomfort of the initial healing, and the difficulty of oral hygiene. Due to these factors, mini-implants became widely used. They have little limitations related to the local of implantation, the surgical procedure of insertion is relatively simple and the control of direction and quantify of the force is simple to be done. These improvements were obtained due to decrease of the size, but these changes could result on significant changes to the bone-implant interface. Since, the orthodontic treatment has to be done as fast as possible. The purpose of this work is to analyze the bone healing reactions to immediately loaded mini-implant of titanium alloy grade 4 by histological, fluorescent and SEM observation, by histomorphometric analysis and by removal torque test. Material and method: Seventy two mini-implants were inserted in eighteen New Zealand rabbits. Four mini-implants were put in the right tibiae of each rabbit and two of then were loaded immediately with 100 gf. Subcutaneous injections of fluorescent labels were administrated in defined periods. The animals were euthanized after 1, 4 and 12 weeks, performing three time analysis and the tibias were dissected and prepared to microcopy analysis and to removal torque test. Results: The results indicated that all the mini-implants remained stable during experimental time. The SEM findings indicated no differences between load and unload group in one and four weeks period, although, the 12 weeks loaded group demonstrated more mature bone formation than the unload group in the same time. These findings suggest that the force can be applied after insertion of the mini-implant without compromises their stability.

Osseointegration interface of calcified bone and endosseous implants

1992 ◽  
Vol 50 (2) ◽  
pp. 1096-1097
Author(s):  
K.E. Krizan ◽  
J.E. Laffoon ◽  
M.J. Buckley
Keyword(s):  
Structure And Function ◽  
Titanium Implants ◽  
En Bloc ◽  
Endosseous Implants ◽  
Ultrastructural Studies ◽  
The Past ◽  
Cacodylate Buffer ◽  
One Year ◽  
And Function

With increase use of tissue-integrated prostheses in recent years it is a goal to understand what is happening at the interface between haversion bone and bulk metal. This study uses electron microscopy (EM) techniques to establish parameters for osseointegration (structure and function between bone and nonload-carrying implants) in an animal model. In the past the interface has been evaluated extensively with light microscopy methods. Today researchers are using the EM for ultrastructural studies of the bone tissue and implant responses to an in vivo environment. Under general anesthesia nine adult mongrel dogs received three Brånemark (Nobelpharma) 3.75 × 7 mm titanium implants surgical placed in their left zygomatic arch. After a one year healing period the animals were injected with a routine bone marker (oxytetracycline), euthanized and perfused via aortic cannulation with 3% glutaraldehyde in 0.1M cacodylate buffer pH 7.2. Implants were retrieved en bloc, harvest radiographs made (Fig. 1), and routinely embedded in plastic. Tissue and implants were cut into 300 micron thick wafers, longitudinally to the implant with an Isomet saw and diamond wafering blade [Beuhler] until the center of the implant was reached.

scholarly journals In Vivo Study for Clinical Application of Dental Stem Cell Therapy Incorporated with Dental Titanium Implants

Materials ◽  
2021 ◽  
Vol 14 (2) ◽  
pp. 381
Author(s):  
Hyunmin Choi ◽  
Kyu-Hyung Park ◽  
Narae Jung ◽  
June-Sung Shim ◽  
Hong-Seok Moon ◽  
...  
Keyword(s):  
Stem Cells ◽  
Bone Formation ◽  
Alveolar Bone ◽  
Human Mesenchymal Stem Cells ◽  
Titanium Implants ◽  
Osteogenic Potential ◽  
Induction Medium ◽  
Radiographic Analysis ◽  
New Bone Formation

The aim of this study was to investigate the behavior of dental-derived human mesenchymal stem cells (d-hMSCs) in response to differently surface-treated implants and to evaluate the effect of d-hMSCs on local osteogenesis around an implant in vivo. d-hMSCs derived from alveolar bone were established and cultured on machined, sandblasted and acid-etched (SLA)-treated titanium discs with and without osteogenic induction medium. Their morphological and osteogenic potential was assessed by scanning electron microscopy (SEM) and real-time polymerase chain reaction (RT-PCR) via mixing of 5 × 106 of d-hMSCs with 1 mL of Metrigel and 20 μL of gel-cell mixture, which was dispensed into the defect followed by the placement of customized mini-implants (machined, SLA-treated implants) in New Zealand white rabbits. Following healing periods of 2 weeks and 12 weeks, the obtained samples in each group were analyzed radiographically, histomorphometrically and immunohistochemically. The quantitative change in osteogenic differentiation of d-hMSCs was identified according to the type of surface treatment. Radiographic analysis revealed that an increase in new bone formation was statistically significant in the d-hMSCs group. Histomorphometric analysis was in accordance with radiographic analysis, showing the significantly increased new bone formation in the d-hMSCs group regardless of time of sacrifice. Human nuclei A was identified near the area where d-hMSCs were implanted but the level of expression was found to be decreased as time passed. Within the limitations of the present study, in this animal model, the transplantation of d-hMSCs enhanced the new bone formation around an implant and the survival and function of the stem cells was experimentally proven up to 12 weeks post-sacrifice.

Calcium Phosphate-Coated Titanium Implants in the Mandible: Limitations of the in vivo Minipig Model

2020 ◽  
Vol 61 (6) ◽  
pp. 177-187
Author(s):  
Till Kämmerer ◽  
Tony Lesmeister ◽  
Victor Palarie ◽  
Eik Schiegnitz ◽  
Andrea Schröter ◽  
...  
Keyword(s):  
Calcium Phosphate ◽  
Statistical Difference ◽  
Surface Modifications ◽  
Titanium Implants ◽  
In Vivo Model ◽  
Implant Surface ◽  
Press Fit ◽  
Endosseous Implant ◽  
Bone To Implant Contact

Introduction: We aimed to compare implant osseointegration with calcium phosphate (CaP) surfaces and rough subtractive-treated sandblasted/acid etched surfaces (SA) in an in vivo minipig mandible model. Materials and Methods: A total of 36 cylindrical press-fit implants with two different surfaces (CaP, n = 18; SA, n = 18) were inserted bilaterally into the mandible of 9 adult female minipigs. After 2, 4, and 8 weeks, we analyzed the cortical bone-to-implant contact (cBIC; %) and area coverage of bone-to-implant contact within representative bone chambers (aBIC; %). Results: After 2 weeks, CaP implants showed no significant increase in cBIC and aBIC compared to SA (cBIC: mean 38 ± 5 vs. 16 ± 11%; aBIC: mean 21 ± 1 vs. 6 ± 9%). Two CaP implants failed to achieve osseointegration. After 4 weeks, no statistical difference between CaP and SA was seen for cBIC (mean 54 ± 15 vs. 43 ± 16%) and aBIC (mean 43 ± 28 vs. 32 ± 6). However, we excluded two implants in each group due to failure of osseointegration. After 8 weeks, we observed no significant intergroup differences (cBIC: 18 ± 9 vs. 18 ± 20%; aBIC: 13 ± 8 vs. 16 ± 9%). Again, three CaP implants and two SA implants had to be excluded due to failure of osseointegration. Conclusion: Due to multiple implant losses, we cannot recommend the oral mandibular minipig in vivo model for future endosseous implant research. Considering the higher rate of osseointegration failure, CaP coatings may provide an alternative to common subtractive implant surface modifications in the early phase post-insertion.

scholarly journals Micro/nano-textured hierarchical titanium topography promotes exosome biogenesis and secretion to improve osseointegration

2021 ◽  
Vol 19 (1) ◽  
Author(s):  
Zhengchuan Zhang ◽  
Ruogu Xu ◽  
Yang Yang ◽  
Chaoan Liang ◽  
Xiaolin Yu ◽  
...  
Keyword(s):  
Gene Expression ◽  
Titanium Surface ◽  
Titanium Implants ◽  
Extracellular Secretion ◽  
Exosome Biogenesis ◽  
Marrow Mesenchymal Stem Cells ◽  
Proliferation In Vitro ◽  
Extracellular Environment

Abstract Background Micro/nano-textured hierarchical titanium topography is more bioactive and biomimetic than smooth, micro-textured or nano-textured titanium topographies. Bone marrow mesenchymal stem cells (BMSCs) and exosomes derived from BMSCs play important roles in the osseointegration of titanium implants, but the effects and mechanisms of titanium topography on BMSCs-derived exosome secretion are still unclear. This study determined whether the secretion behavior of exosomes derived from BMSCs is differently affected by different titanium topographies both in vitro and in vivo. Results We found that both micro/nanonet-textured hierarchical titanium topography and micro/nanotube-textured hierarchical titanium topography showed favorable roughness and hydrophilicity. These two micro/nano-textured hierarchical titanium topographies enhanced the spreading areas of BMSCs on the titanium surface with stronger promotion of BMSCs proliferation in vitro. Compared to micro-textured titanium topography, micro/nano-textured hierarchical titanium topography significantly enhanced osseointegration in vivo and promoted BMSCs to synthesize and transport exosomes and then release these exosomes into the extracellular environment both in vitro and in vivo. Moreover, micro/nanonet-textured hierarchical titanium topography promoted exosome secretion by upregulating RAB27B and SMPD3 gene expression and micro/nanotube-textured hierarchical titanium topography promoted exosome secretion due to the strongest enhancement in cell proliferation. Conclusions These findings provide evidence that micro/nano-textured hierarchical titanium topography promotes exosome biogenesis and extracellular secretion for enhanced osseointegration. Our findings also highlight that the optimized titanium topography can increase exosome secretion from BMSCs, which may promote osseointegration of titanium implants.

scholarly journals Titanium oral implants: surface characteristics, interface biology and clinical outcome

2010 ◽  
Vol 7 (suppl_5) ◽  
Author(s):  
Anders Palmquist ◽  
Omar M. Omar ◽  
Marco Esposito ◽  
Jukka Lausmaa ◽  
Peter Thomsen
Keyword(s):  
Surface Properties ◽  
Cellular Response ◽  
Randomized Clinical Trials ◽  
Three Dimensional ◽  
Cell Communication ◽  
Surface Characteristics ◽  
Titanium Implants ◽  
Material Surface ◽  
Oral Implants

Bone-anchored titanium implants have revolutionized oral healthcare. Surface properties of oral titanium implants play decisive roles for molecular interactions, cellular response and bone regeneration. Nevertheless, the role of specific surface properties, such as chemical and phase composition and nanoscale features, for the biological in vivo performance remains to be established. Partly, this is due to limited transfer of state-of-the-art preparation techniques to complex three-dimensional geometries, analytical tools and access to minute, intact interfacial layers. As judged by the available results of a few randomized clinical trials, there is no evidence that any particular type of oral implant has superior long-term success. Important insights into the recruitment of mesenchymal stem cells, cell–cell communication at the interface and high-resolution imaging of the interface between the surface oxide and the biological host are prerequisites for the understanding of the mechanisms of osseointegration. Strategies for development of the next generation of material surface modifications for compromised tissue are likely to include time and functionally programmed properties, pharmacological modulation and incorporation of cellular components.

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