scholarly journals Genetic Polymorphismsin the Naga tribes of Nagaland with reference to Blood group

2019 ◽  
Vol 16 (3) ◽  
pp. 555-563
Author(s):  
Magdalene Kiewhuo ◽  
Rollen Yanthan ◽  
Milepo Vese ◽  
Mary Swu ◽  
Medonguno Kiso ◽  
...  
Keyword(s):  
Blood Group ◽  
Blood Groups ◽  
Gene Frequencies ◽  
Original Population ◽  
Northern India ◽  
Genetic Level ◽  
And Migration ◽  
Group B ◽  
Relationship Of ◽  
The Relationship

Northern India is one of the oldest geophysical regions of human evolution and migration in the world. Genetic and anthropological studies have shown that the peopling the subcontinent is characterized by a complex history, contributed from different ancestral populations. Genetic level studies of polymorphisms always associated with health and diseases of population becoming the need of hours. The present study was aimed to explore the relationship of ABO blood groups association of populations and to assess the prevalence of blood groups in different categories of Northern India and to compare our results with other studies conducted in India. Blood samples from 155 unrelated individuals was collected from Naga tribal settlements Blood groups of individuals were evaluated with the presence of antigen using monoclonal antibody by a standard blood typing are protocol, Gene frequencies was calculated by Hardy-Weinberg method. The blood group O 67 (43.23%) was the commonest group prevalent in donors followed by group B 45 (29.03%), A 33(21.29%) and AB 10 (6.45%). The Rh negative was not observed in female donors, whereas in male it was found to be 1.3%.Data among tribal suggest their common origin as well as a drift from an original population due to the possible founder effect among tribal Naga Ten Tribal

scholarly journals Blood type mystery

2021 ◽  
Vol 30 (2) ◽  
pp. 91-93
Author(s):  
Inga Tymofiychuk ◽  
Svetlana Semenenko
Keyword(s):  
Blood Group ◽  
Allergic Diseases ◽  
Blood Groups ◽  
Blood Type ◽  
Systematic Change ◽  
Gene Frequencies ◽  
History Of ◽  
Group A ◽  
Group B ◽  
Immunological Protection

In ancient times there was blood a symbol of life flow and energy. It was believed that it gives strength. Red paint and wine were used in traditional rites.Blood type is able to tell a lot of interesting things about its "owner" facts. Having information about your own blood type can be better to understand yourself and your body. The purpose of the article. In Article studies on the history of medicine, which form new ones, are considered ideas about the formation of blood groups. The novelty of the study due to the fact that the idea of ​​blood groups from year to year replenished with new data, which encourages the historical sketch. Main part. With increasing population and changing the environment reduces the possibility to get meat food. As a result, this led to the emergence "Vegetarian" second blood group A. Resettlement of peoples in Europe is the reason for the predominance of people with the second blood group there at this time. It is believed that the homeland of the gene of the third group B is located in the foothills of the Himalayas, in present-day India and Pakistan. The fourth blood group AB arose as a result of mixing holders of gene A and carriers of gene B. Today only 6% Europeans have a fourth blood type, which is the youngest in ABO system. The uniqueness of this group in the inheritance of high immunological protection, which is manifested in resistance to autoimmune and allergic diseases. Conclusions. Evolution human is impossible without a systematic change in gene frequencies population. Is evolution continuing now? Thoughts sometimes contradictory. Some believe that man has reached the top evolutionary tree, others disagree with such conclusions.

scholarly journals Assessment of Gene Frequencies of Human Platelet Alloantigens in Rivers-State, Nigeria Based on ABO/Rhesus Blood Groups Distribution

2021 ◽  
pp. 23-31
Author(s):  
J. E. Wenah-Emmanuel ◽  
E. M. Eze ◽  
E. O. Nwachuku ◽  
E. Wenah ◽  
Z. A. Jeremiah
Keyword(s):  
Ethnic Groups ◽  
Blood Group ◽  
Human Platelet ◽  
Blood Groups ◽  
Curve Analysis ◽  
State University ◽  
Gene Frequencies ◽  
Port Harcourt ◽  
Group B ◽  
Rivers State

Aim: The aim of this study was to assess the Gene Frequencies of Human Platelet Alloantigens in Rivers-State, Nigeria based on ABO/Rhesus blood groups distribution Study Design:   A randomized controlled trial. Place and Duration of Study: Rivers State University Medical Centre, Port Harcourt, Safety Molecular Pathology Laboratory, Enugu State, Justcare clinical laboratory Port Harcourt Rivers State and University of Port Harcourt Teaching Hospital, between October 2019 and March 2020. Methodology: The subjects consisted of apparently healthy individuals who were of Rivers State origin totaling 104 persons aged 17 to 42 years. They were under-graduate and post graduate students of Rivers State University of Port Harcourt. Five major ethnic groups were considered which included Ikwerre, Ogoni, Ijaw, Etche and Ogba. Their demographic information was collected using a sample register and a questionnaire. Samples were collected from the antecubital vein. 10ml of blood was collected, 5ml was transferred into EDTA sample bottle (Ethylene diamine tetracetic acid) while 2ml was dispensed into plain bottle and labeled accordingly. Serological testing including HIV (RVS) screening, HBsag, HCV and VDRL were all as part of the inclusion criteria immediately after samples were collected. The remaining sample was analyzed using genotyping of Human Platelet Antigens by High Resolution Melting Curve Analysis Polymerase Chain Reaction (HRM-PCR), while tile method also known as forward/cell grouping method which is based on haem-agglutination reaction was used for ABO/Rh blood grouping. The melt curve analysis was done using the MicPCR software while the frequency analysis was done using Number Cruncher Statistical Software (NCSS) Version 13. GraphPad Prism Version 8.0.2 was used to determine the statistical significance between the various HPA genotypes and the ethnic groups and p-values of < 0.05 were considered to be statistically significant. Results were presented in percentages, mean+/- standard deviation and in tables Results: The results showed that the A+ blood group had highest frequencies of 19.2% and 17.7% for HPA-5 b/b and HPA-4 a/a, while the least was 0.8% each for HPA-3 a/a, HPA-4 b/b and HPA-5. For blood group B+, the highest were 20.0% (HPA-5 b/b) and 16.7% (HPA-3 b/b), and the least were 5.0% each for HPA-1 b/b and HPA-4 a/b, while blood group B-  had highest frequencies for HPA-1 a/a, HPA-2 b/b, HPA-3 b/b, HPA-4 a/b and HPA-5 b/b (20.0% each). The blood group O+ HPA gene patterns had their highest values at 19.7% (HPA-5 b/b), 16.5% (HPA-4 a/a) and 13.7% (HPA-3 b/b) and the least was 7.9% (HPA-1 a/b), while for the blood group O-, the highest was observed for HPA-3 b/b and HPA-5 b/b (20.0% each) and the least for HPA-1 a/a and a/b, HPA-2 a/b and b/b, and HPA-4 a/b and b/b (10.0% each). Conclusion: Based on the results, we conclude that A+ blood group had highest HPA frequencies. Whilst, the highest for blood group B+ were (HPA-5 b/b) and (HPA-3 b/b), and blood group B- had highest frequencies for HPA-1 a/a, HPA-2 b/b, HPA-3 b/b, HPA-4 a/b and HPA-5 b/b. The blood group O+ HPA gene patterns had their highest values (HPA-5 b/b), (HPA-4 a/a) and (HPA-3 b/b) and the least was (HPA-1 a/b), while for the blood group O-, the highest was observed for HPA-3 b/b and HPA-5 b/b and the least for HPA-1 a/a and a/b, HPA-2 a/b and b/b, and HPA-4 a/b and b/b.

scholarly journals ABO Blood Groups and Risk of Glioma

2021 ◽  
Author(s):  
Ana Azanjac Arsic
Keyword(s):  
Blood Group ◽  
Blood Groups ◽  
Abo Blood Groups ◽  
Increased Risk ◽  
Hereditary Factors ◽  
The One ◽  
Von Willebrand ◽  
Relationship Of ◽  
The Relationship

Gliomas are one of the most common primary brain tumors and the etiology of gliomas remains unknown in most cases. The aim of this case–control study was to investigate possible association between incidence in relation to glioma and certain blood groups. This study included 100 histopathologically verified cases of glioma and 200 age and sex-matched controls without malignant diseases that were admitted to the same hospital. The results revealed that the patients with group AB were at 3.5-fold increased risk of developing glioma compared to the patients with other ABO blood groups. In this particular study, there was more male patients with glioma with the blood group AB. However, mechanisms that explain the relationship between the blood groups ABO and a cancer risk are unclear. Several hypotheses have been proposed, including the one with a modulatory role of blood group ABO antigens. In addition, the blood group ABO system regulates the level of circulating proinflammatory and adhesion molecules which play a significant role in the tumorigenesis process. Additionally, the recent discovery that includes the von Willebrand factor (vWF) as an important modulator of angiogenesis and apoptosis provides one plausible explanation as regards the role of the blood group ABO in the tumorigenesis process. To our knowledge, this is the first study that examined the relationship of blood group in patients diagnosed with glioma among the Serbian population. Moreover, for the first time our study results suggested that blood group AB increased the risk of glioma. The results of this study suggested that the blood group AB could be one of hereditary factors which had an influence on the occurrence of glioma. The further research is needed on a larger sample, to confirm these findings and the possible mechanisms by which the ABO system contributes to the pathology of glioma.

scholarly journals ABO groups can play a role in susceptibility and severity of COVID-19

2021 ◽  
Vol 15 (1) ◽  
Author(s):  
S. Samra ◽  
M. Habeb ◽  
R. Nafae
Keyword(s):  
Blood Group ◽  
Abo Blood Group ◽  
Infection Group ◽  
Mechanically Ventilated ◽  
Blood Group A ◽  
Group A ◽  
Study Population ◽  
Group B ◽  
The Relationship ◽  
Seriously Ill

Abstract Background A few people infected by the coronavirus become seriously ill, while others show little to no signs of the symptoms, or are asymptomatic. Recent researches are pointing to the fact that the ABO blood group might play an important role in a person’s susceptibility and severity of COVID-19 infection. Aim of the study: try to understand the relationship between ABO groups and COVID-19 (susceptibility and severity). Results A total of (507) patients were included in this study. The study population was divided based on the ABO blood group into types A+, A−, B+, AB, O+, and O−. Blood group A was associated with high susceptibility of infection: group A, 381 (75.1%); and less common in group O, 97 (19.2%), group B, 18 (3.5%), and group AB, 11 (2.2%). The severity of COVID-19 infection was common in non-blood group O where (20 (7.1%), 4 (26.7%), 2 (11%), and 1 (9%) in type A+, A−, B+, and AB, respectively), while in type O 3.1%. And mechanically ventilated patients were 22 (5.9%), 2 (13.4%), 2 (11.1%), and 1 (1%). Mortality was high in blood groups A and B, 16 (4.37%) and 1 (5.5%), respectively, while in blood group O, it was 1%. Conclusion The incidence, severity, and mortality of COVID-19 were common in non-blood group O. While blood group O was protected against COVID-19.

scholarly journals Distribution of ABO and Rh blood groups in Nepalese medical students: a report

2000 ◽  
Vol 6 (1) ◽  
pp. 156-158
Author(s):  
T. Pramanik ◽  
S. Pramanik
Keyword(s):  
Medical Students ◽  
Blood Group ◽  
Blood Groups ◽  
Blood Group A ◽  
Group A ◽  
Group B ◽  
Group Distribution

The frequencies of ABO and rhesus blood groups vary from one population to another. We studied blood group distribution in 120 Nepalese students; 34% were blood group A, 29% group B, 4% group AB and 32.5% group O. The frequency of Rh-negative blood was 3.33% and Rh-positive 96.66%

scholarly journals DISTRIBUTION OF ABO AND RH (D) BLOOD GROUPS AMONG BLOOD DONORS IN DISTRICT MARDAN, PAKISTAN

1969 ◽  
Vol 3 (2) ◽  
pp. 318-322
Author(s):  
MUHAMMAD KHALID ◽  
NAILA ASLAM ◽  
MUHAMMAD SIYAR ◽  
RASHID AHMAD
Keyword(s):  
Blood Group ◽  
Blood Donors ◽  
Local Community ◽  
Healthy Adult ◽  
Blood Groups ◽  
Abo Blood Groups ◽  
Cross Sectional ◽  
Group B ◽  
Abo Blood Grouping ◽  
Blood Grouping

OBJECTIVE: To find out the distribution of ABO and Rh (D) blood groups among blood donors in districtMardan and to help transfusion services in the area.STUDY DESIGN: Cross sectional descriptive study.MATERIALS AND METHODS: The study was conducted in DHQ Hospital Mardan from 1st January2012 to 31st December 2012. A total of 2893 healthy adult, blood donors (both volunteer and directed) fromdistrict Mardan were included. Two ml of blood anti-coagulated with EDTA was taken and both ABO andRh (D) blood groups were determined using commercially available anti-sera of Biolaboratories. Thedistribution ofABO and Rh blood groups in the local community were then calculated.RESULTS: Among ABO blood groups “ B” (27.97%) was the most prevalent, followed by “0” (27.93%),“ A” (24.75%) and “ AB” (19.36%). Group Rh positive (94.30%) was more prevalent than Rh negative(5.70%). Similarly 0+ve (26.65%) was most frequent followed by B+ve (26.17%), A+ve (23.16%), AB+ve(18.32%), B've(1.80%),Ave(l.59%),O ve( 1.28%) and ABve( 1.04%).CONCLUSION: Blood group 'B' was most frequent among the ABO blood groups and Rh (D) positiveamong Rh blood groups while0+vewas the most frequent blood group in the study population.KEYWORDS: ABO Blood grouping, Rh (D) blood grouping, Mardan.

scholarly journals Blood Groups of Recipients of COVID-19 Convalescent plasma

2021 ◽  
Vol 156 (Supplement_1) ◽  
pp. S131-S131
Author(s):  
J M Petersen ◽  
D Jhala
Keyword(s):  
Blood Group ◽  
Asian American ◽  
Medical Center ◽  
Blood Groups ◽  
Control Population ◽  
Control Group ◽  
Plasma Therapy ◽  
Unrelated Control ◽  
Significant Difference ◽  
Group B

Abstract Introduction/Objective COVID -19 Convalescent plasma therapy (CCP) is under an FDA Emergency Use Authorization to treat hospitalized patients with COVID-19. However, being ill enough to require hospitalization for COVID-19 is a negative outcome. There is also contradictory literature on whether ABO blood group is associated with worse outcomes with COVID-19 disease. Therefore, we share a regional Veterans Administration Medical Center (VAMC) experience comparing the blood groups of patients intended to receive CCP to a control group of patients positive for SARS-CoV-2. Methods/Case Report A retrospective review of all patients who had CCP ordered in the year 2020 was performed to identify the blood group of these patients, which was compared to a control population of positive patients early in the pandemic (March 17th, 2020 to May 20th, 2020). Results (if a Case Study enter NA) A total of 15 patients had CCP ordered as part of their care with an age range of 56-85 (average 69.7) years of age, entirely male composition, and a racial breakdown of 13 African Americans (86.7%), 1 Caucasian American (6.7%), and 1 Asian American (6.7%). The blood group distribution amongst these 15 patients for CCP was 1 AB+ (6.7%), 5 A+ (33.3%), 4 B+ (26.7%), and 5 O+ (33.3%). The unrelated control population consisted of 81 SARS-CoV-2 positive patients whose blood groups were distributed as 3 group AB (3.7%), 21 group A (25.9%), 15 group B (18.5%), and 42 group O (51.8%). A Chi squared test did not show a statistically significant difference between the two groups in ABO composition. Conclusion The ABO proportions of patients for whom CCP was ordered compared to the control group was not statistically significant. This provides support to the literature arguing that ABO may not be related to worse outcomes such as hospitalization or need for CCP transfusion.

Cytoskeleton interactions in the ascus development and sporulation of Sordaria macrospora

1993 ◽  
Vol 104 (3) ◽  
pp. 883-898 ◽  
Author(s):  
C. Thompson-Coffe ◽  
D. Zickler
Keyword(s):  
Spindle Pole ◽  
Sordaria Macrospora ◽  
Filamentous Ascomycete ◽  
Spindle Pole Bodies ◽  
Double Label ◽  
Butanedione Monoxime ◽  
Myosin Interaction ◽  
And Migration ◽  
Relationship Of ◽  
The Relationship

The organization of actin during meiosis and sporulation in the ascus of the filamentous ascomycete Sordaria macrospora was determined by immunofluorescence without removal of the cell wall. Actin is present as a dense cortical network of microfilaments (MF) and plaques, a perinuclear shell of actin in prophase I of meiosis, and a complex array of MF involved in alignment of prespore nuclei and closure of spore cell membranes. The relationship of actin to the previously examined microtubule system of the ascus was determined by double-label immunofluorescence. The cytoskeletal inhibitors nocodazole, cytochalasin D and 2,3-butanedione monoxime were used to examine the roles of actin and myosin in ascus development. Microfilament and microtubule arrays are interdependant; disruption of one network results in abnormalities in the other. Both microfilaments and actin-myosin interaction are required for separation and migration of duplicated spindle pole bodies, septation and sporulation

Identity, Belonging and Migration: Beyond Constructing ‘Others’

2008 ◽  
pp. 38-53 ◽  
Author(s):  
Paul Jones ◽  
Michał Krzyżanowski
Keyword(s):  
And Migration ◽  
Relationship Of ◽  
The Relationship

‘Identity, Belonging and Migration: Beyond Constructing ‘Others’’, written by Paul Jones and Michael Krzyanowksi, addresses similar themes to the chapter that comes before it by seeking to discourage the uncritical application of the concept of identity, which the authors argue is not always helpful when assessing the relationship of migrants to collectives.

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