scholarly journals Phytochemical Analysis, Antipyretic and Antifungal Activities of Cyrtomium Caryotideum

2018 ◽  
Vol 15 (3) ◽  
pp. 577-589 ◽  
Author(s):  
Shakir Ullah ◽  
Gul Jan ◽  
Farzana Gul Jan ◽  
Siraj Khan ◽  
Maria Khattak ◽  
...  
Keyword(s):  
Cardiac Glycosides ◽  
Research Work ◽  
Chloroform Extract ◽  
Positive Control ◽  
Phytochemical Analysis ◽  
Zone Of Inhibition ◽  
Pharmacological Activities ◽  
Antifungal Activities ◽  
Brewer Yeast ◽  
Phytochemical Investigation

In the present research work the phytochemical investigation of methanolic, ethanolic and chloroform extracts of Cyrtomium caryotideum, Anti-pyretic and antifungal activities in methanolic, ethanolic and chloroform extracts was carried out. The phytochemicals analysis showing the presence of carbohydrates, flavonoids, phlobatannins, alkaloids, saponins, tannins, phenols, terpenoids, cardiac glycosides was present in methanolic and ethanolic extracts, while alkaloids, phlobatannins, glycosides and protein were absent and quantative phytochemistry showed the flavonoids in chloroform extract as (14.20±0.15mg/ml), Alkaloids (12.10±0.15mg/ml), phenolics (10.45± 0.10mg/ml), Saponins (06.22±0.14mg/ml) and Tannins (04.60±0.65 mg/ml). The pharmacological activities such as, Anti-pyretic was carried out by brewer yeast induced pyrexia. The dose of 600 mg/kg of extract showed remarkable anti-pyretic activity (59.43%) when compared with positive control paracetamol (37.24oC) inhibition (73.23%).In antifungal activity the most active among the extracts was with (17.00±0.48 mm) zone of inhibition at the concentration of18 mg/µl against Verticellium. Fallowed by Pythium (16.27±0.93mm), Acremonium (16.20±1.89mm) and Trichoderma (16.11± 0.82) with concentration of 12 mg/µl.

Phytochemical Analysis and Anthelmintic Activity of Salsola imbricata

2019 ◽  
Vol 41 (1) ◽  
pp. 198-198
Author(s):  
Muhammad Ajaib Muhammad Ajaib ◽  
Saleha Farooq Saleha Farooq ◽  
Khalid Mohammed Khan Khalid Mohammed Khan ◽  
Shahnaz Perveen and Shazia Shah Shahnaz Perveen and Shazia Shah
Keyword(s):  
Cardiac Glycosides ◽  
Anthelmintic Activity ◽  
Chloroform Extract ◽  
Reducing Sugar ◽  
Minimum Time ◽  
Bark Extract ◽  
Phytochemical Analysis ◽  
Fruit Extract ◽  
Phytochemical Investigation

Phytochemical investigation and anthelmintic activity of Salsola imbricata Forssk was carried out. Phytochemical analysis showed the presence of anthraquinones, reducing sugar, tannins, saponins, flavonoids, alkaloids and cardiac glycosides. Analysis of anthelmintic activity exhibited that bark extract of S. imbricata is more potent than fruit extract. Minimum time for paralysis and death of worms (9 and#177; 0.6 and 13 and#177; 0.2 min.) was taken by chloroform extract of bark at concentration of 100 mg/mL whereas fruit extract of chloroform was taken minimum time for paralysis and death of worms (10 and#177; 1.1 and 16 and#177; 0.1min.) at concentration of 100 mg/mL.

scholarly journals Phytochemical Screening, Antimicrobial and Antioxidant Activities of Sonchus Oleraceus l (Leaves) Extracts

2020 ◽  
pp. 1-4
Author(s):  
Hatim MY Hamadnalla ◽  
◽  
Mahdi Abd Elmageed Mohammed ◽  
Keyword(s):  
Staphylococcus Aureus ◽  
Bacillus Subtilis ◽  
Methanol Extract ◽  
Antioxidant Activities ◽  
Salmonella Typhi ◽  
Chloroform Extract ◽  
Antioxidant Potential ◽  
Phytochemical Analysis ◽  
Zone Of Inhibition ◽  
Sonchus Oleraceus

The objective of this study to examine phytochemical analysis of sonchus oleraceus l, (asteraceae) (moliata) extracts which were extracted by four solvents, petroleum ether, chloroform, methanol and distill water and to assess their potential antibacterial against four standard bacteria gram-positive and gramnegative (bacillus subtilis staphylococcus aureu, salmonella typhi, and pscudomona aeruginosa) and antioxidant activities. (moliata) extracts using cold maceration method to extract sonchus oleraceus l, (asteraceae) locally known as (moliata) extracts, where dpph assay and paper disc diffusion assay were employed to evaluate the antioxidant and antibacterial activities respectively. The results showed that tannins, triterpenes, a sterols, flavonoids and cardiac glycosides compounds were present in the sonchus oleraceus l, (asteraceae) lives (moliata) extracts. The methanol extract of leaves showed high antioxidant potential (77± 0.03 % ) and chloroform showed low antioxidant potential activity (4±0.09) compare with propyl gallate as standard (93± 0.010 %) against dpph. Chloroform extract was effective and give moderate zone of inhibition against staphylococcus aureus. Methanol extract was effective and showed moderate zone of inhibition against staphylococcus aureus, bacillus subtilis, salmonella typhi and pseudomonas aeruginosa.

scholarly journals Antimicrobial and phytochemical evaluation of Datura Stramonium (Jimsonweed) on selected microorganisms

2021 ◽  
Vol 2 (2) ◽  
pp. 245-256
Author(s):  
Joy Nkeiruka Dike-Ndudim ◽  
Chiletam Nwadiuto Amadi ◽  
Chizaram Winners Ndubueze
Keyword(s):  
Escherichia Coli ◽  
Aspergillus Fumigatus ◽  
Datura Stramonium ◽  
Diffusion Method ◽  
Phytochemical Analysis ◽  
Zone Of Inhibition ◽  
Dry Extract ◽  
Antifungal Activities ◽  
Antibacterial And Antifungal Activities ◽  
Antibacterial And Antifungal

The purpose of this work was to determine the antibacterial and antifungal activities of Datura stramonium on selected microorganisms, and to evaluate its phytochemical properties. The dry and wet leaves of D. stramonium were collected, extracted using ethanol and water, and assessed for antibacterial and antifungal activities at different concentrations (25mg, 12.5mg, 6.25mg, and 3.12mg) by disc diffusion method. The clinical isolates of Staphylococcus aureus, Streptococcus pyogenes, Escherichia coli, Salmonela typhi, Aspergillus fumigatus and Candida albicans were used. The highest zone of inhibition for bacteria was shown with ethanolic dry extract (11.3±3.4) at 25mg/ml and the lowest with aqueous dry extract (4.0±1.4) at 25mg/ml against Escherichia coli. The highest zone of inhibition for fungi was shown with ethanolic dry extract (10±1.4) at 25mg/ml against Aspergillus fumigatus and the lowest was with ethanolic wet extract (2.0±0.0) at 25mg/ml against Candida albican.The phytochemical analysis result showed the presence of tannin (1.757%), phenol (1.149%), flavonoid (6.325%), alkaloid (8.552%), phytate (2.671%), and hydrogen cyanide (4.175%). The chromatographic analysis showed the presence of over 40 elements with the highest as hydrazine (41%) and methyl hydrogen disulphide (41%). In this study, D. stramonium leaf extracts showed significant antibacterial and antifungal activities due to the presence of the phytochemical and bioactive compounds. This upholds the native utility of this plant to treat bacterial and fungal infections. Conclusively, this plant would serve as treatment alternatives for infections and basis for sources of antimicrobial agent.

scholarly journals Evaluation of Antimicrobial Activity of Sida cordifolia Leaf Extract

2019 ◽  
pp. 1-7 ◽  
Author(s):  
Dhanapal Venkatachalam ◽  
Samuel Thavamani ◽  
Aneesh C. Sebastian ◽  
V. B. Anju ◽  
Christy Mathew ◽  
...  
Keyword(s):  
Antimicrobial Activity ◽  
Antibacterial Activity ◽  
Pathogenic Fungus ◽  
Chloroform Extract ◽  
Diffusion Method ◽  
Zone Of Inhibition ◽  
Antifungal Activities ◽  
Antibacterial And Antifungal Activities ◽  
Sida Cordifolia ◽  
Antibacterial And Antifungal

Objective: The objective of the study was to evaluate in-vitro efficacy of antibacterial, and antifungal activities of chloroform extract of leaf of Sida cordifolia L. against some human pathogenic bacterial and fungal strains. S. cordifolia (Malvaceae) is used as anti-rheumatic, analgesic, antipyretic, anti-asthmatic, nasal decongestant, antiviral, laxative, diuretic, aphrodisiac, hypoglycemic, hepatoprotective and in the treatment of Parkinson disease. Methodology: Chloroform extract of S.cordifolia was used for antimicrobial screening. Antibacterial activity was tested against pathogenic bacterial strains Eschericha coli and Staphylococcus aureus. Also antifungal activity was tested against one human pathogenic fungal strain i.e. Candida albicans. Antibacterial and antifungal activities of S. cordifolia extract was carried out by using disc diffusion method. Results: Chloroform extract of S. cordifolia showed the largest zone of inhibition (10mm) against S. aureus at 50µgm/mL and no zone of inhibition against E.coli at 50µgm/ml. Chloroform extract has shown more potent antibacterial activity against S.aureus. Chloroform extract was found to be more effective against human pathogenic fungus C. albicuns. The zone of inhibition of chloroform extract was 10mm.The phytochemical screening demonstrated the presence of different types of compounds like alkaloids, tannins and phenolic compounds which may contribute for the anti-microbial action of this plant.  Conclusions: The results concludes that chloroform extract of S. cordifolia leaf possess antimicrobial activity.

Preliminary phytochemical screening, isolation and structural elucidation of chloroform leaf extracts of Maesa lanceolata

2019 ◽  
Author(s):  
Chem Int
Keyword(s):  
Cardiac Glycosides ◽  
Leaf Extract ◽  
Chloroform Extract ◽  
Phytochemical Analysis ◽  
Spectroscopic Methods ◽  
Phytochemical Screening ◽  
Leaf Extracts ◽  
Standard Procedures ◽  
Phytochemical Constituents ◽  
First Time

The aim of this study was to screen the phytochemical constituents, isolate and elucidate the structure of chloroform extracts from the leaves of Maesa lanceolata. The qualitative phytochemical analysis of the leaf extract of Maesa lanceolata was done following standard procedures and the tests revealed the presence of cardiac glycosides and saponins in the crude extracts. The chloroform extract of the leaves of M. lanceolata led to the isolation of one compound, C1. Structure determination was accomplished by means of spectroscopic methods (IR, 13C and 1H NMR). According to the spectral data (IR, 1HNMR, 13CNMR and DEPT), probably Myrsenene was identified which is reported for the first time from M. lanceolata.

scholarly journals PHYTOCHEMICAL INVESTIGATION AND PHARMACOLOGICAL ACTIVITIES OF HELIOTROPIUM CURASSAVICUM LINN

2019 ◽  
Vol 49 (2) ◽  
pp. 105-109
Author(s):  
W. WASIULLAH ◽  
Saleem JAN ◽  
A. A. SHAD ◽  
A. BASIT ◽  
F. ULLAH
Keyword(s):  
Antioxidant Activity ◽  
Positive Control ◽  
Negative Control ◽  
Total Phenolic ◽  
Pharmacological Activities ◽  
Phenolic Contents ◽  
Phytochemical Investigation ◽  
In Vitro Antibacterial Activity ◽  
Pure Dmso

The current study was focused on the phytochemical investigation and pharmacological activities of the various fractions (methanolic crude, defatted methanolic, n-hexane, dichloromethane, ethylacetate and water) of H. curassavicum. The various plant extracts were examined for the total phenolic contents by taking Gallic acid as a standard, antioxidant scavenging assay by using DPPH (2, 2diphenyl-1-picrylhydrazy) & ABTS [2, 2-azinobis (3ethylbenzthiazoline-6-sulphonic acid)] free radicals, antifungal assay by using Terbinafine solution in DMSO as positive control and pure DMSO as negative control and in-vitro antibacterial activity. Methanolic crude extract showed high phenolic contents and significant antioxidant activity (both DPPH & ABTS). All other fractions were also found to have significant potential.

scholarly journals Evaluation of Antioxidant and Antihyperhipidemic Activity of Pterospermum acerifolium (Sterculiaceae) In Vitro

2017 ◽  
Vol 9 (4) ◽  
Author(s):  
Hemlata Hemlata ◽  
Asija Rajesh ◽  
Charanjeet Singh ◽  
Kumawat Radhey Shyam
Keyword(s):  
Oxidative Stress ◽  
Antioxidant Activity ◽  
High Performance ◽  
Cardiac Glycosides ◽  
Research Work ◽  
Computer Assisted ◽  
Phytochemical Analysis ◽  
Standard Drug ◽  
Antihyperlipidemic Activity

The objective of present research work was to determine the antioxidant and antihyperlipidemic activity in the leaves of Pterospermum acerifolium belonging to family Sterculiaceae. The phytochemical analysis of leaves of Pterospermum acerifolium showed the presence of anthraquinones, cardiac glycosides, flavonoids, saponins and tannins etc. Oxidative compounds are responsible for prognosis of many diseases like Alzheimer’s disease, ischemic heart disease, Parkinson disease, hyperlipidemia and atherosclerosis. Antioxidants are the compounds responsible for curing such ailments that are formed by oxidative stress to the cells. Antioxidant activity of bark of Pterospermum acerifolium was determined by 1, 1- diphenyl-2-picrylhydrazyl radical (DPPH). Ascorbic acid and finofibrate was used as standard drug and antihyperlipidemic activity was determine by computer-assisted high-performance liquid chromatography and determine the various types of lipoprotein like LDL, VLDL and HDL.

scholarly journals Anti-epileptic potentials of the partitioned fractions of chamaecrista mimosoides

2020 ◽  
Vol 8 (1) ◽  
pp. 89
Author(s):  
Asinamai N. Medugu ◽  
James Yakubu ◽  
Hussaini I. Marte ◽  
Timothy . ◽  
S. Yerima
Keyword(s):  
Body Weight ◽  
Cardiac Glycosides ◽  
Research Work ◽  
Scientific Basis ◽  
Positive Control ◽  
Maximal Electroshock ◽  
Phytochemical Study ◽  
Antiepileptic Activity ◽  
Acute Toxicity Study ◽  
Whole Plant

This research work aimed to establish scientific basis for the use of Chamaecrista mimosoides, in traditional medicine as anti-epileptic medication. The whole plant part of Chamaecrista mimosoides was extracted with ethanol and screened for phytochemicals. Acute toxicity study was carried out using Lorke’s method and the antiepileptic activity was evaluated using maximal electroshock induced seizure test in day-old chicks, pentylenetetrazole (PTZ) and strychnine using mice. The phytochemical study revealed the presence of saponins, cardiac glycosides, tannins, flavonoids, terpenoids and cardenolides. Both the chloroform, ethylacetate and n-butanol portions at 100, 250, and 500mg/kg body weight did not protect the chicks against tonic hind limb extension (THLE) in maximal electro-shock test (MEST). The chloroform and n-butanol portions at doses of 250 and 500 mg/kg body weight protected 40% and 60% of mice against clonic spasm induced by pentylenetetrazole, while ethyl-acetate soluble portion did not protect the mice against clonic spasm induced by pentylenetetrazole at all doses used when compared to Valproic acid (200 mg/kg) protected all the mice (100%) against clonic spasm induced by pentylenetetrazole. The chloroform soluble portion at the doses of 100, 250 and 500 mg/kg body weight protected 40%, 100%, 100% against death induced by strychnine, while ethylacetate and n-butanol portions did not protect the rats against death induced by strychnine but prolonged the onset of convulsion. In all the tests, phenobarbitone (20 mg/kg) was used as positive control and protected 80% of mice against convulsion induced by strychnine. The antiepileptic investigation suggests that the chloroform portion of Chamaecrista mimosoides has a promising antiepileptic activity.  

scholarly journals Evaluation of pharmacological potentials of the ethanolic extract of a mushroom (Ganoderma lucidum) grown in FCT

2014 ◽  
Vol 2 (01) ◽  
pp. 01-07
Author(s):  
V. A. Etim ◽  
S. Abubakar ◽  
U. K. Asemota ◽  
O. E. Okereke ◽  
G. H. Ogbadu
Keyword(s):  
Ganoderma Lucidum ◽  
Cardiac Glycosides ◽  
Bacterial Isolate ◽  
Research Work ◽  
Antibacterial Properties ◽  
Ethanolic Extract ◽  
Diffusion Method ◽  
Klebsiella Pneumonia ◽  
Phytochemical Analysis ◽  
Biochemical Tests

The aim of this research work is to evaluate the pharmacological potentials of the mushroom Ganoderma lucidium grown in Federal Capital Territory Abuja, Nigeria. Phytochemical, antioxidant and antibacterial properties of ethanolic extract were carried out. The phytochemical analysis of the ethanolic extract revealed the presence of pharmacological constituents such as: steroids, triterpenoid, carbohydrate, cardiac glycosides and glycosides .The antibacterial activity of the extract was conducted using well agar diffusion method on four clinical bacterial isolate which are identified using various standard biochemical tests. The extract shows activity on: Escherichia coli (12mm), Klebsiella pneumonia (12mm), Proteus mirabilis (13mm) and Streptococcus spp (14mm) at 1000mg/ml respectively .The antioxidant potentiality of the extract was also evaluated using the stable radical 1,1- Diphenyl-l-pienyl hydroxyl (DPPH) and the IC50 of the standards and extract was obtained at 0.06, 0.13, and 0.23 respectively.

scholarly journals Quantitative Phytochemical Analysis and Antifungal Susceptibility of Azardirachta indica against Some Strains of Candida albicans

2019 ◽  
pp. 1-14 ◽  
Author(s):  
A. D. M. Owoyale ◽  
M. Galadimma ◽  
S. Y. Daniyan ◽  
N. Adabara
Keyword(s):  
Candida Albicans ◽  
Crude Extract ◽  
Inhibitory Activity ◽  
Antifungal Susceptibility ◽  
Research Work ◽  
Diffusion Method ◽  
Phytochemical Analysis ◽  
Zone Of Inhibition ◽  
A Value ◽  
Crude Extracts

This research work was focus on determining the quantitative phytochemical analysis and antifungal susceptibility of Azardirachta indica against some strains of Candida albicans. The leaves of Azardirachta indica was susccessively extracted using reflux method of extraction. Quantitative phytochemical screenings were done to determine the amounts of phytochemical that are present in the crude extracts. The result showed that the extract of Azardirachta indica (neem) possessed active principles which include: Alkaloids, saponins, flavonoids, phenols and tannin which were present in the crude extracts. The antifungal activity of the extracts was assayed against three different strains (P37005, RM1000 & SC5314) The antifungal susceptibility test of the crude extracts against the strains were determined at different concentrations of 40, 60, 80 and 100 mg/ml using the  agar well diffusion method. The n- hexane and methanol crude extract showed inhibitory activity compared to that of ethyl acetate that had no inhibitory activity. The highest mean zone of inhibition (MZI) was 15.00±1.00 mm which was recorded for n-hexane leaf extract at a concentration of 100 mg/ml against strain RM1000 (isolate: S2). Although the standard antibiotics (Fluconazole) used in this study showed a much higher zone of inhibition than that of the n-hexane and methanol crude extract. The MIC and MFC value for n-hexane crude extracts were 12.5 mg/ml and 50 mg/ml respectively against strain P37005 (Isolate:S1)likewise, the n-hexane crude extract had a value of 6.25 mg/ml and 50 mg/ml. However, the methanol crude extract showed a value of 6.25 mg/ml and 100 mg/ml respectively against SC5314 (isolate:S3).

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