The Synthesis of Silver Salts of Halogenated and Fatty Acids, Potential Precursors for The Synthesis of Silver Nanoparticles

2014 ◽  
Vol 11 (3) ◽  
pp. 1245-1252
Author(s):  
V.N. Glushko ◽  
N.Y. Sadovskaya ◽  
L.I. Blokhina ◽  
S.K. Belus ◽  
V.V. Grokhovsky
2021 ◽  
Vol 14 (2) ◽  
pp. 139
Author(s):  
Mohammad Azam Ansari ◽  
Sarah Mousa Maadi Asiri ◽  
Mohammad A. Alzohairy ◽  
Mohammad N. Alomary ◽  
Ahmad Almatroudi ◽  
...  

The current study demonstrates the synthesis of fatty acids (FAs) capped silver nanoparticles (AgNPs) using aqueous poly-herbal drug Liv52 extract (PLE) as a reducing, dispersing and stabilizing agent. The NPs were characterized by various techniques and used to investigate their potent antibacterial, antibiofilm, antifungal and anticancer activities. GC-MS analysis of PLE shows a total of 37 peaks for a variety of bio-actives compounds. Amongst them, n-hexadecanoic acid (21.95%), linoleic acid (20.45%), oleic acid (18.01%) and stearic acid (13.99%) were found predominately and most likely acted as reducing, stabilizing and encapsulation FAs in LIV-AgNPs formation. FTIR analysis of LIV-AgNPs shows some other functional bio-actives like proteins, sugars and alkenes in the soft PLE corona. The zone of inhibition was 10.0 ± 2.2–18.5 ± 1.0 mm, 10.5 ± 2.5–22.5 ± 1.5 mm and 13.7 ± 1.0–16.5 ± 1.2 against P. aeruginosa, S. aureus and C. albicans, respectively. LIV-AgNPs inhibit biofilm formation in a dose-dependent manner i.e., 54.4 ± 3.1%—10.12 ± 2.3% (S. aureus), 72.7 ± 2.2%–23.3 ± 5.2% (P. aeruginosa) and 85.4 ± 3.3%–25.6 ± 2.2% (C. albicans), and SEM analysis of treated planktonic cells and their biofilm biomass validated the fitness of LIV-AgNPs in future nanoantibiotics. In addition, as prepared FAs rich PLE capped AgNPs have also exhibited significant (p < 0.05 *) antiproliferative activity against cultured HCT-116 cells. Overall, this is a very first demonstration on employment of FAs rich PLE for the synthesis of highly dispersible, stable and uniform sized AgNPs and their antibacterial, antifungal, antibiofilm and anticancer efficacy.


2019 ◽  
Vol 38 (8) ◽  
pp. 962-973 ◽  
Author(s):  
JS Hussein ◽  
W Rasheed ◽  
T Ramzy ◽  
M Nabeeh ◽  
M Harvy ◽  
...  

Objective: To investigate the ability of docosahexaenoic acid (DHA)-loaded silver nanoparticles (AgNPs) in facilitating the incorporation of DHA in the cell membrane, improve cell membrane structure, and attenuate endothelial dysfunction in experimental diabetes. Methods: DHA/AgNPs were prepared using a nanoprecipitation technique. Fifty male albino rats were used in this study; 10 of them were served as the control group and 40, as the experimental groups, were injected with streptozotocin. Then, the experimental groups were subdivided into diabetic, diabetic treated with DHA, diabetic treated with AgNPs, and diabetic treated with DHA/AgNPs groups. Results: DHA/AgNPs have small spherical size as proved from ultraviolet–visible spectroscopy, transmission electron microscope, dynamic light scattering, and scanning electron microscope techniques. Cell membrane cholesterol and triglycerides showed a significant elevation in the diabetic group compared to the control, but treatment with DHA and DHA/AgNPs caused a significant reduction in both. Treatment with AgNPs and DHA/AgNPs caused a significant improvement in asymmetric dimethylarginine and nitric oxide levels compared to the diabetic group. Cell membrane fatty acids showed that omega-6 polyunsaturated fatty acids (PUFAs) were significantly elevated, while omega-3 PUFA were significantly reduced in the diabetic group compared to the control. There is a significant improvement in the levels of fatty acids in all groups after treatment with DHA, silver, or DHA/AgNPs. Conclusion: DHA/AgNPs are potent agents for the improvement of diabetic complication and endothelial dysfunction in experimental diabetes.


2017 ◽  
Vol 240 ◽  
pp. 80-86 ◽  
Author(s):  
Anna Modrzejewska-Sikorska ◽  
Emilia Konował ◽  
Adam Cichy ◽  
Marek Nowicki ◽  
Teofil Jesionowski ◽  
...  

1949 ◽  
Vol 2 (6) ◽  
pp. 398-403 ◽  
Author(s):  
V. Vand ◽  
A. Aitken ◽  
R. K. Campbell

Nature ◽  
1948 ◽  
Vol 162 (4119) ◽  
pp. 580-582 ◽  
Author(s):  
A. KELLER ◽  
F. KÖRÖSY
Keyword(s):  

2017 ◽  
Vol 47 (6) ◽  
pp. 742-750
Author(s):  
Huaqiao Tan ◽  
Hongfei Shi ◽  
Yonghui Wang ◽  
Wenzhe Zhou ◽  
Xiaojia Feng ◽  
...  

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