Proximate composition, antioxidant and hypoglycaemic potential of aqueous extracts of seeds of Delonix regia on high fat diet and streptozotocin-induced diabetes in female wistar rats

2018 ◽  
Vol 6 (1) ◽  
pp. 33-46
Author(s):  
P. O. Ogboye ◽  
B.M. Onyegeme-Okerenta ◽  
C. Monago-Ighorodje
Keyword(s):  
Proximate Composition ◽  
High Fat Diet ◽  
Wistar Rats ◽  
Aqueous Extracts ◽  
High Fat ◽  
Delonix Regia ◽  
Female Wistar Rats ◽  
Streptozotocin Induced Diabetes

scholarly journals Antioxidant and Ameliorative Potential of Aqueous Seed extracts of Delonix regia on High Fat Diet and Streptozotocin Induced Diabetes in Female Wistar Rats

2018 ◽  
Vol 32 (S1) ◽  
Author(s):  
BLESSING MINAOPUNYE ONYEGEME‐OKERENTA ◽  
PHILIP OSEIKHUENMHEN OGBOYE ◽  
COMFORT CHINAZO MONAGO‐IGHORODJE ◽  
IFEOMA NWAMAKA MONAGO
Keyword(s):  
High Fat Diet ◽  
Wistar Rats ◽  
High Fat ◽  
Delonix Regia ◽  
Female Wistar Rats ◽  
Streptozotocin Induced Diabetes ◽  
Seed Extracts

Effects of chia (Salvia hispanica L.) on oxidative stress and inflammation in ovariectomized adult female Wistar rats

2019 ◽  
Vol 10 (7) ◽  
pp. 4036-4045 ◽  
Author(s):  
Bárbara Pereira da Silva ◽  
Renata Celi Lopes Toledo ◽  
Marcella Duarte Villas Mishima ◽  
Maria Eliza de Castro Moreira ◽  
Christiane Mileib Vasconcelos ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Adult Female ◽  
High Fat Diet ◽  
Wistar Rats ◽  
Lipid Profiles ◽  
Ovariectomized Rats ◽  
High Fat ◽  
Salvia Hispanica ◽  
Female Wistar Rats ◽  
Salvia Hispanica L

The study investigated the influence of chia consumption on inflammation, oxidative stress, and lipid profiles in female ovariectomized rats fed a high-fat diet.

Amla (Emblica officinalis) improves hepatic and renal oxidative stress and the inflammatory response in hypothyroid female wistar rats fed with a high-fat diet

2018 ◽  
Vol 29 (2) ◽  
pp. 175-184 ◽  
Author(s):  
P. Rajaa Muthu ◽  
Zachariah Bobby ◽  
P. Sankar ◽  
V. Vickneshwaran ◽  
Sajini Elizabeth Jacob
Keyword(s):  
Oxidative Stress ◽  
Inflammatory Response ◽  
High Fat Diet ◽  
Wistar Rats ◽  
Molecular Techniques ◽  
Emblica Officinalis ◽  
High Fat ◽  
Tnf Α ◽  
Female Wistar Rats ◽  
Liver And Kidney

AbstractBackground:We investigated the protective effects of amla (Emblica officinalis) on the pathogenesis of oxidative stress (OS) and inflammatory response in hypothyroid rats fed with a high-fat diet (HFD) as an experimental model of hypothyroidism (HT) with obesity.Methods:A total of 80 female wistar rats (5-months-old) were divided into eight different groups. Propylthiouracil (PTU) and HFD were used to induce the experimental HT and obesity, respectively. The euthyroid and hypothyroid rats were fed either normal chow or HFD with and without amla extract (AE, 100 mg/kg bw/day) for 6 weeks. The blood and tissues, liver and kidney OS and inflammatory parameters were studied using appropriate biochemical and molecular techniques.Results:PTU and HFD per se caused OS and inflammatory response as evidenced by increased plasma MDA, TNF-α, CRP and GPx in association with decreased levels of TAS and reduced glutathione (GSH). The proteomic analysis revealed that the expressions of pERK, pP38, TNF-α, IL6, COX2 and NOX-4 were up-regulated in the liver and kidney of these rats. In addition, all these metabolic derangements were further augmented when HT was followed by the addition of HFD. This suggested that there was a synergism between HT and the intake of HFD on the development of OS and inflammatory response.Conclusions:The treatment with amla fruit extract significantly restored the redox imbalance and inflammatory signaling and ameliorated OS and inflammatory response, suggesting the use of this natural compound as an alternative remedy or adjuvant for the management of metabolic complications concomitant with HT.

Sodium butyrate recovers high-fat diet-fed female Wistar rats from glucose dysmetabolism and uric acid-associated cardiac tissue damage

2019 ◽  
Vol 392 (11) ◽  
pp. 1411-1419 ◽  
Author(s):  
Caroline Badejogbin ◽  
Damilare E. Areola ◽  
Kehinde S. Olaniyi ◽  
Oluwaseun A. Adeyanju ◽  
Isaac O. Adeosun
Keyword(s):  
Uric Acid ◽  
Sodium Butyrate ◽  
Tissue Damage ◽  
High Fat Diet ◽  
Wistar Rats ◽  
Cardiac Tissue ◽  
High Fat ◽  
Female Wistar Rats

Plantago maxima leaves extract inhibits adipogenic action of a high-fat diet in female Wistar rats

2013 ◽  
Vol 53 (3) ◽  
pp. 831-842 ◽  
Author(s):  
Alexey A. Tinkov ◽  
Olga N. Nemereshina ◽  
Elizaveta V. Popova ◽  
Valentina S. Polyakova ◽  
Viktor A. Gritsenko ◽  
...  
Keyword(s):  
High Fat Diet ◽  
Wistar Rats ◽  
High Fat ◽  
Female Wistar Rats

Melatonin ameliorates endocrine dysfunction and defective sperm integrity associated with high‐fat diet‐induced obesity in male Wistar rats

Andrologia ◽  
2021 ◽  
Author(s):  
Comfort Abisola Oladele ◽  
Christopher Oloruntoba Akintayo ◽  
Olabimpe Caroline Badejogbin ◽  
Adesola Adedotun Oniyide ◽  
Adams Olalekan Omoaghe ◽  
...  
Keyword(s):  
High Fat Diet ◽  
Wistar Rats ◽  
Endocrine Dysfunction ◽  
High Fat ◽  
Diet Induced Obesity ◽  
Male Wistar Rats

Particular Matter of Motor Vehicle Exposure and High-Fat Diet Effects on Kidney Histopathology, Creatinine, and Malondialdehyde (MDA) Levels in Wistar Rats

2021 ◽  
Vol 5 (3) ◽  
pp. 124-128
Author(s):  
Rizka Veni ◽  
Awal Prasetyo ◽  
Muflihatul Muniroh
Keyword(s):  
High Fat Diet ◽  
Wistar Rats ◽  
Motor Vehicle ◽  
Histopathological Change ◽  
Normal Diet ◽  
Control Group ◽  
High Fat ◽  
Control Group Design ◽  
Treatment Groups ◽  
Significant Difference

This study aims to analyze the effect of combination of motor vehicle particular matter exposure and high-fat diet in kidney histopathology, creatinine levels, and MDA levels in Wistar rats. This study used a posttest-only control group design. Eighteen healthy male Wistar rats were divided into three groups. The intervention groups received motor vehicle fume exposure for 100 s with normal diet (X1) or high-fat diet (X2), and the control group received no exposure (C). Data analysis was processed with a SPSS 25.0 computer program by using the one-way ANOVA test followed by post hoc LSD. The degree of kidney histopathological damage showed significant differences between the X1 and X2 groups when compared with the control group (p < 0.05). The results of the creatinine level examination found a significant difference between the X2 and C groups (p < 0.05) and the treatment groups X1 and X2 (p < 0.05). The results of kidney MDA level examination showed a significant difference between the treatment groups (X1 and X2) and the control group (p < 0.05). The combination of particular matter of motor vehicle fumes exposure and high-fat diet could induce kidney damage through histopathological change and increased creatinine levels and kidney MDA levels in Wistar rats.

Histopathological and biochemical effects of aqueous extract of Tragopogon graminifolius on the liver tissues of Wistar rats fed with high-fat diet

2018 ◽  
Vol 28 (5) ◽  
pp. 1197-1203 ◽  
Author(s):  
Mohammad Mahdi Zangeneh ◽  
Saman Salmani ◽  
Akram Zangeneh ◽  
Reza Khedri ◽  
Mohammad Saeid Zarei
Keyword(s):  
Aqueous Extract ◽  
High Fat Diet ◽  
Wistar Rats ◽  
High Fat ◽  
Biochemical Effects ◽  
Tragopogon Graminifolius ◽  
Liver Tissues
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