scholarly journals Treadmill exercise improves spatial learning ability by enhancing brain-derived neurotrophic factor expression in the attention-deficit/hyperactivity disorder rats

2014 ◽  
Vol 10 (3) ◽  
pp. 162-167 ◽  
Author(s):  
Hye Im Jeong ◽  
Eun-Sang Ji ◽  
Su-Hyun Kim ◽  
Tae-Wook Kim ◽  
Sang-Bin Baek ◽  
...  
Keyword(s):  
Attention Deficit Hyperactivity Disorder ◽  
Spatial Learning ◽  
Attention Deficit ◽  
Neurotrophic Factor ◽  
Treadmill Exercise ◽  
Brain Derived Neurotrophic Factor ◽  
Learning Ability ◽  
Hyperactivity Disorder ◽  
Factor Expression

scholarly journals Peripheral Brain-Derived Neurotrophic Factor and Contactin-1 Levels in Patients with Attention-Deficit/Hyperactivity Disorder

2019 ◽  
Vol 8 (9) ◽  
pp. 1366 ◽  
Author(s):  
Liang-Jen Wang ◽  
Chih-Ching Wu ◽  
Min-Jing Lee ◽  
Miao-Chun Chou ◽  
Sheng-Yu Lee ◽  
...  
Keyword(s):  
Attention Deficit Hyperactivity Disorder ◽  
Attention Deficit ◽  
Neurotrophic Factor ◽  
Performance Test ◽  
Continuous Performance Test ◽  
Brain Derived Neurotrophic Factor ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Hyperactivity Disorder ◽  
Drug Naïve

Brain-derived neurotrophic factor (BDNF) facilitates neuronal growth and plasticity, and is crucial for learning and memory. Contactin-1 (CNTN1) is a member of the subfamily of neural immunoglobulin and is involved in the formation of axon connections in the developing nervous system. This cross-sectional study investigates whether BDNF and CNTN1 affect susceptibility to attention deficit/hyperactivity disorder (ADHD). A total of 136 drug-naïve patients with ADHD (108 boys and 28 girls) and 71 healthy controls (45 boys and 26 girls) were recruited. Blood samples were obtained to measure the plasma levels of BDNF and CNTN1 in each child. We found that BDNF levels in the ADHD boys exceeded those in the control boys, but BDNF levels in the ADHD girls were lower than those in the control girls. Boys who had higher BDNF levels performed worse on the Wechsler Intelligence Scale for Children—Fourth Edition, but girls who had higher BDNF levels made fewer omission errors in the Conners’ Continuous Performance Test. However, CNTN1 level did not differ significantly between patients and controls, and were not correlated to ADHD characteristics, regardless of gender. The findings suggest BDNF may influence sex-specific susceptibility to ADHD, but CNTN1 was not associated with ADHD pathophysiology.

Changes in the serum levels of brain-derived neurotrophic factor in adults with attention deficit hyperactivity disorder after treatment with atomoxetine

2013 ◽  
Vol 231 (7) ◽  
pp. 1389-1395 ◽  
Author(s):  
Josep Antoni Ramos-Quiroga ◽  
Margarida Corominas-Roso ◽  
Gloria Palomar ◽  
Nuria Gomez-Barros ◽  
Marta Ribases ◽  
...  
Keyword(s):  
Attention Deficit Hyperactivity Disorder ◽  
Attention Deficit ◽  
Neurotrophic Factor ◽  
Serum Levels ◽  
Brain Derived Neurotrophic Factor ◽  
Hyperactivity Disorder
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