scholarly journals 13C NMR Study of Poly(N-vinylpyrrolidone)–Cu(II) Complex in Aqueous Solution

1994 ◽  
Vol 26 (4) ◽  
pp. 479-483 ◽  
Author(s):  
Ken-ichi Tsuchiya ◽  
K Takegoshi ◽  
Kunio Hikichi
Keyword(s):  
Aqueous Solution ◽  
13C Nmr ◽  
Nmr Study

scholarly journals A 13C-NMR study of the inhibition of papain by a dipeptide-glyoxal inhibitor

2002 ◽  
Vol 366 (3) ◽  
pp. 983-987 ◽  
Author(s):  
Jonathan LOWTHER ◽  
Aleksandra DJURDJEVIC-PAHL ◽  
Chandralal HEWAGE ◽  
J. Paul G. MALTHOUSE
Keyword(s):  
Aqueous Solution ◽  
13C Nmr ◽  
Aqueous Media ◽  
Thiol Group ◽  
Competitive Inhibitor ◽  
Nmr Study

Z-Phe-Ala-glyoxal (where Z is benzyloxycarbonyl) has been synthesized and shown to be a competitive inhibitor of papain with a Ki = 3.30±0.25nM. 13C-NMR has been used to show that in aqueous media, Z-Phe-[2-13C]Ala-glyoxal gives signals at 207.7p.p.m. and 96.3p.p.m. showing that both the α-keto carbon and its hydrate are present. When this inhibitor is bound to papain a single signal at 209.7p.p.m. is observed due to the 13C-enriched carbon. This demonstrates that the glyoxal α-keto carbon is not hydrated when it is bound to papain and that it does not form a thiohemiketal with the thiol group of Cys-25. Z-Phe-[1-13C]Ala-glyoxal has also been synthesized and its aldehyde carbon is fully hydrated in aqueous solution giving signals at 88.7p.p.m. and 90.2p.p.m. when the α-keto carbon and its hydrate are present respectively. When this inhibitor is bound to papain a single signal at 71.04p.p.m. was observed due to the 13C-enriched carbon showing that the 13C-enriched aldehyde carbon forms a thiohemiacetal with Cys-25.

Interactions of D-cellobiose with p-toluenesulfonic acid in aqueous solution: a 13C NMR study

2011 ◽  
Vol 346 (17) ◽  
pp. 2820-2822 ◽  
Author(s):  
Ananda S. Amarasekara ◽  
Onome S. Owereh ◽  
Brian Ezeh
Keyword(s):  
Aqueous Solution ◽  
13C Nmr ◽  
Toluenesulfonic Acid ◽  
Nmr Study

scholarly journals A 13C NMR study of methyl-branched hydrocarbon biosynthesis in the housefly.

1982 ◽  
Vol 257 (19) ◽  
pp. 11305-11314 ◽  
Author(s):  
J W Dillwith ◽  
J H Nelson ◽  
J G Pomonis ◽  
D R Nelson ◽  
G J Blomquist
Keyword(s):  
13C Nmr ◽  
Nmr Study ◽  
Hydrocarbon Biosynthesis

scholarly journals Triglyceride metabolism in 3T3-L1 cells. An in vivo 13C NMR study.

1992 ◽  
Vol 267 (16) ◽  
pp. 11168-11175
Author(s):  
M.R. Soma ◽  
M.P. Mims ◽  
M.V. Chari ◽  
D Rees ◽  
J.D. Morrisett
Keyword(s):  
13C Nmr ◽  
Triglyceride Metabolism ◽  
Nmr Study
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