scholarly journals Masked Hypertension Determined by Self-Measured Blood Pressure at Home and Chronic Kidney Disease in the Japanese General Population: The Ohasama Study

2008 ◽  
Vol 31 (12) ◽  
pp. 2129-2135 ◽  
Author(s):  
Hiroyuki TERAWAKI ◽  
Hirohito METOKI ◽  
Masaaki NAKAYAMA ◽  
Takayoshi OHKUBO ◽  
Masahiro KIKUYA ◽  
...  
2014 ◽  
Vol 142 (1-2) ◽  
pp. 113-117 ◽  
Author(s):  
Amira Peco-Antic ◽  
Dusan Paripovic

Renal hypertension is one of the earliest and the most prevalent complications of pediatric chronic kidney disease (CKD). Among renal patients, hypertension is frequently underdiagnosed and undertreated. For casual blood pressure measurement, the best method is auscultatory, while for ambulatory blood pressure measurement, oscillometric method is the most commonly used. Both casual and ambulatory blood pressure measurement provide more powerful means of diagnosing hypertension. Masked hypertension is a condition in which casual blood pressure is normal but ambulatory blood pressure is elevated. The risk of cardiovascular morbidity and mortality is higher with masked hypertension as compared to the controls. Children and adolescents with CKD are at high risk of cardiovascular disease that has been established as the leading cause of death in patients with end stage renal disease. Left ventricular hypertrophy remains the most thoroughly documented form of end-organ damage caused by hypertension in children and adolescents with CKD. Based on clear evidence on the correlation between blood pressure and cardiovascular morbidity, mortality, and renal function, renal hypertension must be aggressively treated. Target blood pressure for patients with renal hypertension should be at low normal values: <75 percentile for patients without proteinuria and <50 percentile for patients with proteinuria. Renin-angiotensin system antagonists are considered the first choice pharmacological option in hypertensive CKD 2-4 patients while the management of volume overload is the most important in dialysis patients. Successful transplantation can eliminate or significantly improve uremia-related cardiovascular risk factors and increase predicted life expectancy.


2012 ◽  
Vol 81 (3) ◽  
pp. 293-299 ◽  
Author(s):  
Yuichiro Yano ◽  
Shouichi Fujimoto ◽  
Yuji Sato ◽  
Tsuneo Konta ◽  
Kunitoshi Iseki ◽  
...  

2009 ◽  
Vol 13 (6) ◽  
pp. 621-630 ◽  
Author(s):  
Enyu Imai ◽  
Masaru Horio ◽  
Tsuyoshi Watanabe ◽  
Kunitoshi Iseki ◽  
Kunihiro Yamagata ◽  
...  

2019 ◽  
Vol 44 (5) ◽  
pp. 973-983
Author(s):  
Daisuke Uchida ◽  
Ryo Kido ◽  
Hiroo Kawarazaki ◽  
Masaru Murasawa ◽  
Ayami Ando ◽  
...  

Background/Aims: The association of diastolic blood pressure (DBP) with incidence of chronic kidney disease (CKD) in the general population is not well examined. Methods: Using national health check-up database from 2008 to 2011 in the general Japanese population aged 39–74 years, we evaluated the association between DBP and incidence of CKD 2 years later in 127,954 participants without CKD. DBP was categorized by every 5 mm Hg from the lowest (<60 mm Hg) to the highest category (>100 mm Hg) and was further stratified into those with and without antihypertensive medications (BP meds). We calculated the OR for estimating adjusted risk of incident CKD using logistic regression model. Results: Participants were 62% female and 25.9% with BP meds, mean age of 76 years with estimated glomerular filtration rate of 78.2 ± 13.4 and DBP of 76 ± 11 mm Hg. Two years later, 12,379 (9.7%) developed CKD. Compared to DBP 60–64 mm Hg without BP meds as reference, multivariate analysis showed no difference in CKD risk at any DBP category among those without BP meds. However, in those with BP meds, risk increased according to lower DBP from 95 to 60 mm Hg (p for trend 0.05) with OR 1.51 (95% CI 1.14–1.99) in DBP <60 mm Hg. In subgroup analysis within those with or without BP meds, CKD risk was lower at higher DBP (p for trend 0.02) only in those without BP meds. Conclusion: Lower DBP was associated with higher risk of incident CKD only in the general population taking antihypertensive medication.


2012 ◽  
Vol 30 ◽  
pp. e264
Author(s):  
Hiroyuki Takase ◽  
Yasuaki Dohi ◽  
Tateo Okado ◽  
Takamitsu Tanaka ◽  
Tomomi Hashimoto ◽  
...  

2013 ◽  
Vol 31 (12) ◽  
pp. 2410-2417 ◽  
Author(s):  
Atsuhiro Kanno ◽  
Masahiro Kikuya ◽  
Kei Asayama ◽  
Michihiro Satoh ◽  
Ryusuke Inoue ◽  
...  

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