scholarly journals The Relationship between White Blood Cell Count and Risk of Hypertension in Populations with High Prevalence of Smoking

2008 ◽  
Vol 31 (7) ◽  
pp. 1279-1281
Author(s):  
Tomonori OKAMURA ◽  
Makoto WATANABE
Keyword(s):  
Blood Cell ◽  
Cell Count ◽  
White Blood Cell Count ◽  
White Blood Cell ◽  
Blood Cell Count ◽  
High Prevalence ◽  
The Relationship

scholarly journals The Relationship between the White Blood Cell Count and Cigarette Smoking among Japanese Males

1997 ◽  
Vol 39 (4) ◽  
pp. 280-284 ◽  
Author(s):  
Yoshito Momose ◽  
Hiroshi Une ◽  
Haruhiko Ikui ◽  
Hiroji Esaki
Keyword(s):  
Cigarette Smoking ◽  
Blood Cell ◽  
Cell Count ◽  
White Blood Cell Count ◽  
White Blood Cell ◽  
Blood Cell Count ◽  
The Relationship

The relationship between amniotic fluid white blood cell count and funisitis at term

2005 ◽  
Vol 193 (6) ◽  
pp. S114
Author(s):  
Si Eun Lee ◽  
Roberto Romero ◽  
Soon-Sup Shim ◽  
Kyung Chul Moon ◽  
Chong Jai Kim ◽  
...  
Keyword(s):  
Blood Cell ◽  
Amniotic Fluid ◽  
Cell Count ◽  
White Blood Cell Count ◽  
White Blood Cell ◽  
Blood Cell Count ◽  
The Relationship

scholarly journals Differentiated white blood cell count measures as a predictor of weight in anorexia nervosa

BJPsych Open ◽  
2021 ◽  
Vol 7 (S1) ◽  
pp. S246-S246
Author(s):  
Benjamin Cross ◽  
Matthew Cahill
Keyword(s):  
Weight Loss ◽  
Anorexia Nervosa ◽  
Blood Cell ◽  
Cell Count ◽  
White Blood Cell Count ◽  
White Blood Cell ◽  
White Cell Count ◽  
Regression Analyses ◽  
Blood Cell Count ◽  
The Relationship

AimsTo explore the relationship between weight, BMI and differentiated white cell count in patients with anorexia nervosa that have commenced refeeding protocols.Hypotheses: 1. Weight and BMI will be positively correlated with differentiated white blood cell measures.2. Regression analyses will indicate that differentiated white blood cell measures can predict weight and BMI.BackgroundAnorexia nervosa is a serious mental illness with the highest psychiatric mortality rate. It is characterised by an extreme overvaluation of body image and a preoccupation with weight loss that is achieved through calorie restriction, purging or laxative abuse. The eventual malnutrition that is as a result of self-starvation causes significant negative physical sequelae. One such consequence is the detrimental effect that starvation has on the immune system, leading to bone marrow suppression and cytopenias. In obesity, weight loss has been shown to cause reductions in differentiated white blood cell counts, which are often reduced in anorexia. No studies to date have explored whether weight is related to white blood cell count in anorexia, despite being a common finding in patients.MethodAll subjects were inpatients or ex-inpatients on an eating disorder unit in the Wirral, NW England. Subjects were assessed according to an inclusion criterion. 12 consecutive weekly weights, BMIs and differentiated white blood cell measures were collected for analysis in SPSS. Correlational and regression analyses were then performed to examine the relationship between variables.Result302 data points from 26 individuals were used in the final analysis. Weight and BMI both moderately positively correlated with white cell count, r = 0.364 p < 0.001 N = 302 and r = 0.521 p < 0.001 N = 302, respectively. Weight and BMI also moderately positively correlated with all differentiated measures of white blood cell count. Linear regression revealed a significant regression equation between weight, BMI and white blood cell count: (F (1,301) = 22.482, p < 0.001) R2 = 0.69 and (F (1,301) = 112.244 p < 0.001) R2 = 0.272, respectively.ConclusionWe have demonstrated that there is a moderately positive relationship between weight, BMI and differentiated white blood cell measures. Furthermore, in line with our hypotheses, differentiated white blood cell measures have some power to predict weight and BMI. This further implicates the effect that starvation and anorexia nervosa have on the immune system. It also highlights the possibility that it might be possible to use immunological markers in order to deduce whether weights have been falsified by those with anorexia nervosa.

scholarly journals White Blood Cells and Severe COVID-19: A Mendelian Randomization Study

2021 ◽  
Vol 11 (3) ◽  
pp. 195
Author(s):  
Yitang Sun ◽  
Jingqi Zhou ◽  
Kaixiong Ye
Keyword(s):  
Blood Cell ◽  
Cell Count ◽  
White Blood Cell Count ◽  
White Blood Cell ◽  
Blood Cells ◽  
Mendelian Randomization ◽  
Association Studies ◽  
White Blood Cells ◽  
Genome Wide Association Studies ◽  
Blood Cell Count

Increasing evidence shows that white blood cells are associated with the risk of coronavirus disease 2019 (COVID-19), but the direction and causality of this association are not clear. To evaluate the causal associations between various white blood cell traits and the COVID-19 susceptibility and severity, we conducted two-sample bidirectional Mendelian Randomization (MR) analyses with summary statistics from the largest and most recent genome-wide association studies. Our MR results indicated causal protective effects of higher basophil count, basophil percentage of white blood cells, and myeloid white blood cell count on severe COVID-19, with odds ratios (OR) per standard deviation increment of 0.75 (95% CI: 0.60–0.95), 0.70 (95% CI: 0.54–0.92), and 0.85 (95% CI: 0.73–0.98), respectively. Neither COVID-19 severity nor susceptibility was associated with white blood cell traits in our reverse MR results. Genetically predicted high basophil count, basophil percentage of white blood cells, and myeloid white blood cell count are associated with a lower risk of developing severe COVID-19. Individuals with a lower genetic capacity for basophils are likely at risk, while enhancing the production of basophils may be an effective therapeutic strategy.

Sign in / Sign up

Export Citation Format

Share Document