scholarly journals Report of the Working Group for Dietary Salt Reduction of the Japanese Society of Hypertension: (1) Rationale for Salt Restriction and Salt-Restriction Target Level for the Management of Hypertension

2007 ◽  
Vol 30 (10) ◽  
pp. 879-886 ◽  
Author(s):  
Yuhei KAWANO ◽  
Katsuyuki ANDO ◽  
Hideo MATSUURA ◽  
Takuya TSUCHIHASHI ◽  
Toshiro FUJITA ◽  
...  
Keyword(s):  
Working Group ◽  
Japanese Society ◽  
Target Level ◽  
Dietary Salt ◽  
Salt Reduction ◽  
Salt Restriction

scholarly journals Report of the Working Group for Dietary Salt Reduction of the Japanese Society of Hypertension: (2) Assessment of Salt Intake in the Management of Hypertension

2007 ◽  
Vol 30 (10) ◽  
pp. 887-893 ◽  
Author(s):  
Yuhei KAWANO ◽  
Takuya TSUCHIHASHI ◽  
Hideo MATSUURA ◽  
Katsuyuki ANDO ◽  
Toshiro FUJITA ◽  
...  
Keyword(s):  
Working Group ◽  
Japanese Society ◽  
Salt Intake ◽  
Dietary Salt ◽  
Salt Reduction

scholarly journals Factors Affecting Salt Reduction Measure Adoption among Chinese Residents

2021 ◽  
Vol 18 (2) ◽  
pp. 445
Author(s):  
Zeying Huang ◽  
Di Zeng
Keyword(s):  
Logistic Regression ◽  
Food Intake ◽  
Nutrition Education ◽  
Online Survey ◽  
Adaptive Lasso ◽  
Stepwise Logistic Regression ◽  
Salt Reduction ◽  
Salt Restriction ◽  
Salt Diet ◽  
Factors Affecting

China has the highest mortality rate caused by diseases and conditions associated with its high-salt diet. Since 2016, China has initiated a national salt reduction campaign that aims at promoting the usage of salt information on food labels and salt-restriction spoons and reducing condiment and pickled food intake. However, factors affecting individuals’ decisions to adopt these salt reduction measures remain largely unknown. By comparing the performances of logistic regression, stepwise logistic regression, lasso logistic regression and adaptive lasso logistic regression, this study aims to fill this gap by analyzing the adoption behaviour of 1610 individuals from a nationally representative online survey. It was found that the practices were far from adopted and only 26.40%, 22.98%, 33.54% and 37.20% reported the adoption of labelled salt information, salt-restriction spoons, reduced condiment use in home cooking and reduced pickled food intake, respectively. Knowledge on salt, the perceived benefits of salt reduction, participation in nutrition education and training programs on sodium reduction were positively associated with using salt information labels. Adoption of the other measures was largely explained by people’s awareness of hypertension risks and taste preferences. It is therefore recommended that policy interventions should enhance Chinese individuals’ knowledge of salt, raise the awareness of the benefits associated with a low-salt diet and the risks associated with consuming excessive salt and reshape their taste choices.

scholarly journals Systematic review of dietary salt reduction policies: Evidence for an effectiveness hierarchy?

PLoS ONE ◽  
2017 ◽  
Vol 12 (5) ◽  
pp. e0177535 ◽  
Author(s):  
Lirije Hyseni ◽  
Alex Elliot-Green ◽  
Ffion Lloyd-Williams ◽  
Chris Kypridemos ◽  
Martin O’Flaherty ◽  
...  
Keyword(s):  
Systematic Review ◽  
Dietary Salt ◽  
Salt Reduction

Dietary salt restriction accelerates atherosclerosis in apolipoprotein E-deficient mice

2005 ◽  
Vol 180 (2) ◽  
pp. 271-276 ◽  
Author(s):  
Ognen Ivanovski ◽  
Dorota Szumilak ◽  
Thao Nguyen-Khoa ◽  
Michele Dechaux ◽  
Ziad A. Massy ◽  
...  
Keyword(s):  
Apolipoprotein E ◽  
Dietary Salt ◽  
Salt Restriction ◽  
Dietary Salt Restriction ◽  
Deficient Mice

Abstract 16443: Effects of Dietary Salt Intakes on Blood Pressure, Renal Function and Oxidative Stress in Rats Treated With Candesartan

Circulation ◽  
2020 ◽  
Vol 142 (Suppl_3) ◽  
Author(s):  
Gangyi Zhu ◽  
Yanting Yu ◽  
Xiaoyan Wang
Keyword(s):  
Oxidative Stress ◽  
Blood Pressure ◽  
Renal Function ◽  
Kidney Diseases ◽  
Sprague Dawley ◽  
Dietary Salt ◽  
Salt Restriction ◽  
Low Salt ◽  
Receptor Blockers ◽  
And Oxidative Stress

Candesartan is one of angiotensin II type1 receptor blockers(ARB) and commonly used as first-line antihypertensive treatment. Low salt diet is often recommended by clinicians to the patients with hypertension and kidney diseases. However,it is not clear whether salt restriction is beneficial to the patients taking ARB. In order to explore this problem, the impacts of different salt diets on blood pressure (BP),renal function and oxidative stress were determined in 2-3 months old male Sprague Dawley rats treated with candesartan. The rats were randomly divided into 4 groups fed agar-gelled food rationally with NaCl content at 0.01%, 0.8%, 2% and 4% respectively(4-7 rats/group) while all rats were intraperitoneally injected with candesartan at 1mg / kg / day for 7 days. SBP started to decline on day 2 in all except 4% NaCl groups relative to day 0 (recorded 5-6 hrs before the first injection). On day 6, systolic BP (mmHg, tail-cuff, Softron,BP-98A) was lower in 0.8% (103.7+2.3) & 0.01% (101.6+3) groups than 2% (113.5+4.1) & 4% (129.9+4.6) groups (one way ANOVA,LSD test, P<0.05) and correlated positively with food NaCl intakes (R 2 =0.9832). DBP was changed in a similar pattern as SBP. Serum creatinine (μmol/L) was higher in 0.01% group (225+39) than groups of 0.8% (1328+350), 2% (2095+242) and 4% (1576+703) while creatinine clearance (ml/day) was lower in 0.01% group (69.3+9) than groups of 0.8% (43.7+9), 2%(27.7+2) and 4%(29+0.6). In order to determine whether oxidative stress plays any role in the BP regulation and renal function maintenance, we also checked renal protein expression of ROS components. Relative to 0.8% group, renal NOXs were not altered in 0.01% group while NOX1 (145+18,% of 0.8% group), NOX2 (240+54) and NOX4 (197+41) was higher in 2% group than other groups. Mn-SOD (77+7.8), not Cu-Zn SOD, was decreased while HO1 (170+16), not HO2, was increased in 0.01% group. Renal abundance of nitrotyrosine was lower in 0.01% than other groups indicating a decreased oxidative stress, possibly caused by increase in HO1. We concluded that salt restriction with candesartan is beneficial to antihypertensive effect of AT1R blockade but disadvantage to maintenance of renal function. Thus, cautions to choice of low salt intakes are necessary when taking ARB agents.

Differential Regulation of the Epithelial Sodium Channel (ENaC) in Rat Kidney, Lung and Distal Colon in Response to Aldosterone.

Hypertension ◽  
2000 ◽  
Vol 36 (suppl_1) ◽  
pp. 724-724
Author(s):  
Shyama M E Masilamani ◽  
Gheun-Ho Kim ◽  
Mark A Knepper
Keyword(s):  
Sodium Channel ◽  
Epithelial Sodium Channel ◽  
Distal Colon ◽  
Β Subunit ◽  
Dietary Salt ◽  
Α Subunit ◽  
Salt Restriction ◽  
Γ Subunit ◽  
Dietary Salt Restriction ◽  
Epithelial Sodium Channel Enac

P170 The mineralocorticoid hormone, aldosterone increases renal tubule Na absorption via increases in the protein abundances of the α-subunit of the epithelial sodium channel (ENaC) and the 70 kDa form of the γ- subunit of ENaC (JCI 104:R19-R23). This study assesses the affect of dietary salt restriction on the regulation of the epithelial sodium channel (ENaC) in the lung and distal colon, in addition to kidney, using semiquantitative immunoblotting. Rats were placed initially on either a control Na intake (0.02 meq/day), or a low Na intake (0.2 meq/day) for 10 days. The low salt treated rats demonstrated an increase in plasma aldosterone levels at day 10 (control = 0.78 + 0.32 nM; Na restricted = 3.50 + 1.30 nM). In kidney homogenates, there were marked increases in the band density of the α-subunit of ENaC (286 % of control) and the 70 kDa form of γ-subunit of ENaC (262 % of control), but no increase in the abundance of the β-subunit of ENaC. In lung homogenates, there was no significant change in the band densities of the α, β, or γ subunits of ENaC. In distal colon, there was an increase in the band density of the β-subunit of ENaC (311 % of control) and an increase in both the 85 kDa (2355% of control) and 70 kDa (843 % of control) form of the γ subunit of ENaC in response to dietary Na restriction. However, there was no significant difference in the band density of the α-subunit of ENaC. These findings demonstrate tissue specific regulation of the three subunits of ENaC in response to dietary salt restriction.

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