Inhibition of Inward Rectifier K+ Currents by Angiotensin II in Rat Atrial Myocytes: Lack of Effects in Cells from Spontaneously Hypertensive Rats

Kazuhiko SONOYAMA; Haruaki NINOMIYA; Osamu IGAWA; Yasuhiro KAETSU; Yoshiyuki FURUSE; Toshihiro HAMADA; Junichiro MIAKE; Peili LI; Yasutaka YAMAMOTO; Kazuhide OGINO; Akio YOSHIDA; Shin-ichi TANIGUCHI; Yasutaka KURATA; Satoshi MATSUOKA; Toshio NARAHASHI; Goshi SHIOTA; Yoshihisa NOZAWA; Hiroaki MATSUBARA; Masatsugu HORIUCHI; Yasuaki SHIRAYOSHI; Ichiro HISATOME

doi:10.1291/hypres.29.923

Inhibition of Inward Rectifier K+ Currents by Angiotensin II in Rat Atrial Myocytes: Lack of Effects in Cells from Spontaneously Hypertensive Rats

Hypertension Research ◽

10.1291/hypres.29.923 ◽

2006 ◽

Vol 29 (11) ◽

pp. 923-934 ◽

Cited By ~ 4

Author(s):

Kazuhiko SONOYAMA ◽

Haruaki NINOMIYA ◽

Osamu IGAWA ◽

Yasuhiro KAETSU ◽

Yoshiyuki FURUSE ◽

...

Keyword(s):

Angiotensin Ii ◽

Spontaneously Hypertensive Rats ◽

Inward Rectifier ◽

Atrial Myocytes ◽

Hypertensive Rats ◽

Spontaneously Hypertensive ◽

K Currents ◽

In Cells

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Angiotensin II Increases Norepinephrine Turnover in the Anteroventral Third Ventricle of Spontaneously Hypertensive Rats

Hypertension ◽

10.1161/01.hyp.28.2.224 ◽

1996 ◽

Vol 28 (2) ◽

pp. 224-227 ◽

Cited By ~ 3

Author(s):

Akira Tsukashima ◽

Takuya Tsuchihashi ◽

Isao Abe ◽

Kaoru Nakamura ◽

Hideyuki Uchimura ◽

...

Keyword(s):

Angiotensin Ii ◽

Spontaneously Hypertensive Rats ◽

Third Ventricle ◽

Hypertensive Rats ◽

Spontaneously Hypertensive ◽

Norepinephrine Turnover

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Angiotensin II type 1 receptor blocker irbesartan ameliorates vascular function in spontaneously hypertensive rats regardless of oestrogen status

Journal of Hypertension ◽

10.1097/00004872-200207000-00023 ◽

2002 ◽

Vol 20 (7) ◽

pp. 1365-1372 ◽

Cited By ~ 10

Author(s):

Alberto Riveiro ◽

Alejandro Mosquera ◽

Manuela Alonso ◽

Carlos Calvo

Keyword(s):

Angiotensin Ii ◽

Vascular Function ◽

Spontaneously Hypertensive Rats ◽

Receptor Blocker ◽

Hypertensive Rats ◽

Spontaneously Hypertensive

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Differential effect of chronic inhibition of calcium channel and angiotensin II type 1-receptor on aldosterone synthesis in spontaneously hypertensive rats

The Journal of Steroid Biochemistry and Molecular Biology ◽

10.1016/s0960-0760(00)00096-0 ◽

2000 ◽

Vol 74 (3) ◽

pp. 125-136 ◽

Cited By ~ 5

Author(s):

Fumio Otsuka ◽

Toshio Ogura ◽

Hideo Kataoka ◽

Masayuki Kishida ◽

Masami Takahashi ◽

...

Keyword(s):

Angiotensin Ii ◽

Calcium Channel ◽

Differential Effect ◽

Spontaneously Hypertensive Rats ◽

Hypertensive Rats ◽

Spontaneously Hypertensive

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Angiotensin II Type 1 Receptor Blocker Reduces Monocyte Adhesion to Endothelial Cells in Spontaneously Hypertensive Rats

Endocrine Journal ◽

10.1507/endocrj.k07-004 ◽

2007 ◽

Vol 54 (4) ◽

pp. 605-612 ◽

Cited By ~ 3

Author(s):

Fuki IKEDA ◽

Kosuke AZUMA ◽

Takeshi OGIHARA ◽

Yukiko TOYOFUKU ◽

Aiko OTSUKA ◽

...

Keyword(s):

Endothelial Cells ◽

Angiotensin Ii ◽

Spontaneously Hypertensive Rats ◽

Receptor Blocker ◽

Monocyte Adhesion ◽

Hypertensive Rats ◽

Spontaneously Hypertensive

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Role of Endogenous Angiotensin II in the Increased Expression of Growth Factors in Vascular Smooth Muscle Cells from Spontaneously Hypertensive Rats

Journal of Cardiovascular Pharmacology ◽

10.1097/00005344-200101000-00013 ◽

2001 ◽

Vol 37 (1) ◽

pp. 108-118 ◽

Cited By ~ 36

Author(s):

Chikara Satoh ◽

Noboru Fukuda ◽

Wen-Yang Hu ◽

Mari Nakayama ◽

Hirobumi Kishioka ◽

...

Keyword(s):

Smooth Muscle ◽

Growth Factors ◽

Angiotensin Ii ◽

Vascular Smooth Muscle ◽

Smooth Muscle Cells ◽

Vascular Smooth Muscle Cells ◽

Spontaneously Hypertensive Rats ◽

Hypertensive Rats ◽

Spontaneously Hypertensive

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Differential Effects of Angiotensin II Type-1 Receptor Antisense Oligonucleotides on Renal Function in Spontaneously Hypertensive Rats

Hypertension ◽

10.1161/01.hyp.0000171587.44736.ba ◽

2005 ◽

Vol 46 (1) ◽

pp. 58-65 ◽

Cited By ~ 25

Author(s):

Minoru Yoneda ◽

Hironobu Sanada ◽

Junichi Yatabe ◽

Sanae Midorikawa ◽

Shigeatsu Hashimoto ◽

...

Keyword(s):

Renal Function ◽

Angiotensin Ii ◽

Antisense Oligonucleotides ◽

Spontaneously Hypertensive Rats ◽

Hypertensive Rats ◽

Spontaneously Hypertensive ◽

Differential Effects

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Continuous inhibition of the renin–angiotensin system and protection from hypertensive end-organ damage by brief treatment with angiotensin II type 1 receptor blocker in stroke-prone spontaneously hypertensive rats

Life Sciences ◽

10.1016/j.lfs.2004.12.048 ◽

2005 ◽

Vol 77 (18) ◽

pp. 2233-2245 ◽

Cited By ~ 14

Author(s):

Kumiko Takemori ◽

Hiroyuki Ishida ◽

Hiroyuki Ito

Keyword(s):

Angiotensin Ii ◽

Spontaneously Hypertensive Rats ◽

Renin Angiotensin System ◽

Organ Damage ◽

Receptor Blocker ◽

Brief Treatment ◽

Hypertensive Rats ◽

Angiotensin System ◽

Spontaneously Hypertensive

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AT1 receptor‐ independent oxidative stress in angiotensin II (Ang II) infused Male Spontaneously Hypertensive Rats (SHR)

The FASEB Journal ◽

10.1096/fasebj.24.1_supplement.605.14 ◽

2010 ◽

Vol 24 (S1) ◽

Author(s):

Kanchan Bhatia ◽

Jennifer C Sullivan

Keyword(s):

Oxidative Stress ◽

Angiotensin Ii ◽

Spontaneously Hypertensive Rats ◽

At1 Receptor ◽

Ang Ii ◽

Hypertensive Rats ◽

Spontaneously Hypertensive

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Effects of Angiotensin II type I receptor shRNA on blood pressure and left ventricular remodeling in spontaneously hypertensive rats

Experimental Animals ◽

10.1538/expanim.20-0152 ◽

2021 ◽

Author(s):

Jinlian ZHANG ◽

Ying ZHANG ◽

ChuanShi XIAO ◽

YuJie LIU

Keyword(s):

Blood Pressure ◽

Angiotensin Ii ◽

Spontaneously Hypertensive Rats ◽

Ventricular Remodeling ◽

Left Ventricular Remodeling ◽

Left Ventricular ◽

Type I ◽

Hypertensive Rats ◽

Spontaneously Hypertensive

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β-Pro7Ang III is a novel highly selective angiotensin II type 2 receptor (AT2R) agonist, which acts as a vasodepressor agent via the AT2R in conscious spontaneously hypertensive rats

Clinical Science ◽

10.1042/cs20150077 ◽

2015 ◽

Vol 129 (6) ◽

pp. 505-513 ◽

Cited By ~ 15

Author(s):

Mark Del Borgo ◽

Yan Wang ◽

Sanja Bosnyak ◽

Morimer Khan ◽

Pia Walters ◽

...

Keyword(s):

Cardiovascular Disease ◽

Angiotensin Ii ◽

Protein Binding ◽

Binding Site ◽

Spontaneously Hypertensive Rats ◽

Protective Effects ◽

Ang Ii ◽

Hypertensive Rats ◽

Spontaneously Hypertensive

We have synthesized a highly selective compound that is able to target a protein-binding site [called angiotensin (Ang) II type 2 receptor, AT2R] in the cardiovascular system. This research tool will enhance our ability to stimulate AT2R to produce protective effects against cardiovascular disease.

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