scholarly journals The Effects of Short-Term Blood Pressure Variability and Nighttime Blood Pressure Levels on Cognitive Function.

2001 ◽  
Vol 24 (1) ◽  
pp. 19-24 ◽  
Author(s):  
Akiko KANEMARU ◽  
Kazutomi KANEMARU ◽  
Iwao KUWAJIMA
Keyword(s):  
Blood Pressure ◽  
Cognitive Function ◽  
Blood Pressure Variability ◽  
Short Term ◽  
Nighttime Blood Pressure

Abstract 26: Long-term Blood Pressure Variability though Young Adulthood and Cognitive Function in Midlife; The Coronary Artery Risk Development in Young Adults (CARDIA)Study

Circulation ◽  
2014 ◽  
Vol 129 (suppl_1) ◽  
Author(s):  
Yuichiro Yano ◽  
Hongyan Ning ◽  
Norrina Allen ◽  
Jared P. Reis ◽  
Kiang Liu ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Cognitive Function ◽  
Young Adulthood ◽  
Verbal Memory ◽  
Blood Pressure Variability ◽  
Verbal Learning ◽  
Stroop Test ◽  
Psychomotor Speed ◽  
Short Term

Background: Blood pressure variability (BPV) consists of short-term BPV (e.g., diurnal BPV) and long-term BPV (e.g., visit-to-visit BPV). The prospective association of long-term BPV though young adulthood with cognition in midlife is unknown. Methods: CARDIA is a multicenter community-based study that included participants (ppts) aged 18 to 30 years at baseline (Year 0: Y 0 ) in 1985-86 with follow-up examinations at Y 2 , Y 5 , Y 7 , Y 10 , Y 15 , Y 20 , and Y 25 . BP was measured at each exam, and visit-to-visit BPV was assessed by standard deviation (SD), coefficient of variation (CV), maximum minus minimum BP difference (MMD), and average real variability (ARV) across 7 visits (Y 0-20 ). Cognitive function was assessed at Y 25 by the Digit Symbol Substitution Test (DSST, a measure of psychomotor speed; n=2,318), the Rey Auditory Verbal Learning Test (RAVLT, a measure of short-term verbal memory; n=2,321), and the modified Stroop test (executive function; n=2,307). We performed separate multivariable-adjusted linear regression models, and also adjusted for baseline BP (Y 0 ), change of BP (Y 20 -Y 0 ), or cumulative BP from Y 0 to Y 20 (mmHg х year) to determine whether BPV is associated with cognition independent of long-term BP level. Results: At the Y 25 examination, included ppts had a mean age of 50 years, 57% were women and 43% were black. BPV measured by higher SD and ARV in both systolic and diastolic BP was significantly associated with lower DSST and lower RAVLT. SD and ARV remained significant even after further adjustment for baseline BP, change of BP, or cumulative BP (Table). Measures of BPV were not associated with the Stroop test. Associations between the CV and MMD measures of BPV with cognitive function were similar to those of SD (not shown). Conclusions: Long-term BPV over 20-years through young adulthood is associated with worse psychomotor speed and verbal memory in midlife, independent of BP levels. These results may have implications for understanding the pathogenesis of cognitive dysfunction in older adults.

scholarly journals Antihypertensive drug classes have different effects on short-term blood pressure variability in essential hypertension

2014 ◽  
Vol 37 (6) ◽  
pp. 585-590 ◽  
Author(s):  
Natacha Levi-Marpillat ◽  
Isabelle Macquin-Mavier ◽  
Anne-Isabelle Tropeano ◽  
Gianfranco Parati ◽  
Patrick Maison
Keyword(s):  
Blood Pressure ◽  
Essential Hypertension ◽  
Antihypertensive Drug ◽  
Blood Pressure Variability ◽  
Short Term ◽  
Drug Classes

Short-term beat-to-beat but not ambulatory blood pressure variability is correlated to carotid intima-media thickness

2014 ◽  
Vol 19 (5) ◽  
pp. 288-293 ◽  
Author(s):  
Efstathios Manios ◽  
Fotios Michas ◽  
Kimon Stamatelopoulos ◽  
Gerasimos Barlas ◽  
Eleni Koroboki ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Ambulatory Blood Pressure ◽  
Blood Pressure Variability ◽  
Intima Media Thickness ◽  
Carotid Intima Media Thickness ◽  
Short Term ◽  
Media Thickness

Effects of 12 weeks of aerobic versus combined aerobic plus resistance exercise training on short-term blood pressure variability in patients with hypertension

2021 ◽  
Vol 130 (4) ◽  
pp. 1085-1092
Author(s):  
Giuseppe Caminiti ◽  
Ferdinando Iellamo ◽  
Annalisa Mancuso ◽  
Anna Cerrito ◽  
Matteo Montano ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Exercise Training ◽  
Resistance Exercise ◽  
Aerobic Exercise ◽  
Blood Pressure Variability ◽  
Short Term ◽  
Resistance Exercise Training ◽  
Hypertensive Patients ◽  
Combined Exercise ◽  
Resistance Exercises

Combined exercise training (CT) including aerobic plus resistance exercises could be more effective in comparison with aerobic exercise (AT) alone in reducing blood pressure variability (BPV) in hypertensive patients. We report that CT was indeed more effective than AT in reducing short-term BPV, and both exercise modalities reduced BP levels to the same extent. CT appears to be a more appropriate exercise modality if the objective is to reduce BPV in addition to BP levels.

Abstract P199: Higher Circulating Triglycerides are Independently Associated With Greater Short-term Blood Pressure Variability in Middle-aged/older Adults With Obesity

Hypertension ◽  
2017 ◽  
Vol 70 (suppl_1) ◽  
Author(s):  
Rachel E Luehrs ◽  
Graziela Z Kalil ◽  
Seth W Holwerda ◽  
Nealy A Wooldridge ◽  
Jess G Fiedorowicz ◽  
...  
Keyword(s):  
Risk Factors ◽  
Blood Pressure ◽  
Blood Pressure Variability ◽  
Plasma Lipids ◽  
Target Organ Damage ◽  
Density Lipoprotein ◽  
Multiple Linear Regression Model ◽  
Middle Aged ◽  
Short Term ◽  
Cvd Risk

Elevated short-term (24 hour) blood pressure variability (BPV) is associated with subclinical target organ damage and cardiovascular disease (CVD) among middle-aged/older (MA/O) adults with hypertension and obesity. Circulating total cholesterol (TC), low-density cholesterol (LDL-C) and triglycerides (TGs) increase with human obesity and are independent risk factors for CVD. In addition, BPV is increased in mouse models of hyperlipidemia and is normalized with statins. However, whether higher circulating lipoproteins independently contribute to greater short-term BPV among adults with obesity remains unclear. We hypothesized that higher LDL-C, TGs and lower high-density lipoprotein (HDL-C) would be associated with greater short-term BPV among individuals with obesity. Fasting plasma lipids and 24 hour ambulatory BP monitoring were assessed in fifty-six MA/O adults with obesity defined as body mass index (BMI) ≥ 30 kg/m 2 (56% F; age 54±7 yrs; BMI, 38.2±5.6 kg/m 2 ) and at least one other CVD risk factor. There was a significant relation between 24 hour systolic BPV and TC (r=0.30, P=0.03), TGs (r=0.34, P=0.01) and LDL-C (r=0.25, P=0.059), but not HDL-C (r=-0.07, P=0.61). Interestingly, these findings remained significant after adjusting for age, sex, BMI and 24 hour systolic BP (TC: r=0.34, P=0.01; TGs: r=0.39, P<0.01; LDL-C: r=0.31, P=0.03) but HDL-C remained non-significant (r=-0.16, P=0.27). In contrast, other cardiometabolic risk factors such as fasting glucose, insulin, c-reactive protein concentrations, carotid-femoral pulse wave velocity and HOMA-IR were not associated with 24 hour systolic BPV. In a multiple linear regression model that included age, sex, BMI, 24 hour systolic BP, TGs and LDL-C, only fasting TGs (β=0.02 ± 0.01, P=0.02) were a significant correlate of 24 hour systolic BPV (Model R 2 =0.24, P=0.03). Results were the same if TC was substituted for LDL-C in the model. In conclusion, higher plasma TC, LDL-C and TGs are associated with greater 24 hour BPV among MA/O adults with obesity with only TGs being independently associated with BPV. These data suggest that greater variability in BP among MA/O adults with obesity is mediated in part through circulating TGs suggesting that TGs may be a therapeutic target to modify short-term BPV.

A Comparative Study of Short-Term Blood Pressure Variability in Hemodialysis Patients with and without Intradialytic Hypertension

2018 ◽  
Vol 48 (4) ◽  
pp. 295-305 ◽  
Author(s):  
Athanasios Bikos ◽  
Elena Angeloudi ◽  
Evangelos Memmos ◽  
Charalampos Loutradis ◽  
Antonios Karpetas ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Cardiovascular Risk ◽  
Blood Pressure Variability ◽  
Hemodialysis Patients ◽  
Adverse Outcomes ◽  
Short Term ◽  
Ambulatory Bp Monitoring ◽  
Average Real Variability ◽  
Regular Hemodialysis ◽  
Sustained Increase

Background: Short-term blood pressure (BP) variability (BPV) is associated with increased cardiovascular risk in hemodialysis. Patients with intradialytic hypertension have high risk of adverse outcomes. Whether BPV is increased in these patients is not clear. The purpose of this study was to compare short-term BPV in patients with and without intradialytic hypertension. Methods: Forty-one patients with and 82 patients without intradialytic hypertension (intradialytic SBP rise ≥10 mm Hg to > 150 mm Hg) matched in a 1: 2 ratio for age, sex, and hemodialysis vintage were included. All subjects underwent 48-h ambulatory BP monitoring during a regular hemodialysis and the subsequent interdialytic interval. Brachial and aortic BPV were calculated with validated formulas and compared between the 2 groups during the 48-h and the 44-h periods and during the 2 daytime and nighttime periods respectively. Results: During 48-h or 44-h periods and daytime or nighttime, brachial SBP/DBP and aortic SBP/DBP were significantly higher in cases than in controls. All brachial SBP/DBP BPV indexes [SD, weighted SD (wSD), coefficient-of-variation (CV) and average-real-variability (ARV)] were not significantly different between groups during the 48- or 44-h periods (48-h: SBP-ARV 11.59 ± 3.05 vs. 11.70 ± 2.68, p = 0.844, DBP-ARV: 8.60 ± 1.90 vs. 8.90 ± 1.63, p = 0.357). Analysis stratified by day or night between days 1 and 2 revealed, in general, similar results. No significant differences in dipping pattern were observed between groups. Analysis of aortic BPV had similar findings. Conclusions: BPV is similar between those with and without intradialytic hypertension. However, those with intradialytic hypertension have a sustained increase in systolic and diastolic BP during the entire interdialytic interval.

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