scholarly journals Left Ventricular Hypertrophy Is More Prominent in Patients with Primary Aldosteronism than in Patients with Other Types of Secondary Hypertension.

1997 ◽  
Vol 20 (2) ◽  
pp. 85-90 ◽  
Author(s):  
Akiyo Tanabe ◽  
Mitsuhide Naruse ◽  
Kiyoko Naruse ◽  
Mitsuyasu Hase ◽  
Takanobu Yoshimoto ◽  
...  
Keyword(s):  
Left Ventricular Hypertrophy ◽  
Primary Aldosteronism ◽  
Ventricular Hypertrophy ◽  
Secondary Hypertension ◽  
Left Ventricular

Mean platelet volume in patients with primary aldosteronism and its relation to left ventricular hypertrophy

2013 ◽  
Vol 168 (3) ◽  
pp. 3143-3144 ◽  
Author(s):  
Satoshi Kurisu ◽  
Takashi Shimonaga ◽  
Toshitaka Iwasaki ◽  
Naoya Mitsuba ◽  
Ken Ishibashi ◽  
...  
Keyword(s):  
Left Ventricular Hypertrophy ◽  
Primary Aldosteronism ◽  
Mean Platelet Volume ◽  
Ventricular Hypertrophy ◽  
Left Ventricular ◽  
Platelet Volume

Renin a marker for left ventricular hypertrophy in primary aldosteronism: a cohort study.

2021 ◽  
Author(s):  
Anton Köhler ◽  
Anna-Lina Sarkis ◽  
Daniel Alexander Heinrich ◽  
Lisa Müller ◽  
Laura Handgriff ◽  
...  
Keyword(s):  
Left Ventricular Hypertrophy ◽  
Primary Aldosteronism ◽  
Ventricular Hypertrophy ◽  
Specific Treatment ◽  
Plasma Renin ◽  
Left Ventricular ◽  
Treatment Groups ◽  
One Year ◽  
Cardiovascular Benefit

Context: Primary aldosteronism (PA) causes left ventricular hypertrophy (LVH) via hemodynamic factors and directly by aldosterone effects. Specific treatment by mineralocorticoid receptor antagonists (MRA) or adrenalectomy (ADX) has been reported to improve LVH. However, cardiovascular benefit could depend on plasma renin concentration (PRC) in patients on MRA. Patients and Objective: We analyzed data from 184 patients from the Munich center of the German Conn’s Registry, who underwent echocardiography at time of diagnosis and one year after treatment. To assess the effect of PRC on cardiac recovery we stratified patients on MRA according to suppression (n=46) or non-suppression of PRC (n=59) at follow-up and compared them to PA patients after ADX (n=79). Results: At baseline, patients treated by ADX or MRA had comparable left ventricular mass index (LVMI, 61.7 vs 58.9 g/m2.7, p= 0.591). Likewise, patients on MRA had similar LVMI at baseline, when stratified into treatment groups with suppressed and unsuppressed PRC during follow-up (60.0 vs 58.1 g/m2.7, p= 0.576). In all three groups we observed a significant reduction in LVMI following treatment (p<0.001). However, patients with suppressed PRC had no decrease in pro-BNP levels and the reduction of LVMI was less intense than in patients with unsuppressed PRC (4.1 vs 8.2 g/m2.7, p= 0.033) or after ADX (9.3 g/m2.7, p= 0.019). Similarly, in multivariate analysis, higher PRC was correlated with the regression of LVH. Conclusion: PA patients with suppressed PRC on MRA show impaired regression of LVH. Therefore, dosing of MRA according to PRC, could improve their cardiovascular benefit.

scholarly journals Long-Term Control of Arterial Hypertension and Regression of Left Ventricular Hypertrophy With Treatment of Primary Aldosteronism

Hypertension ◽  
2013 ◽  
Vol 62 (1) ◽  
pp. 62-69 ◽  
Author(s):  
Gian Paolo Rossi ◽  
Maurizio Cesari ◽  
Cesare Cuspidi ◽  
Giuseppe Maiolino ◽  
Maria Verena Cicala ◽  
...  
Keyword(s):  
Left Ventricular Hypertrophy ◽  
Arterial Hypertension ◽  
Primary Aldosteronism ◽  
Ventricular Hypertrophy ◽  
Left Ventricular

scholarly journals Effects of hypokalemia and left ventricular hypertrophy on QT interval in patients with primary aldosteronism

2011 ◽  
Vol 152 (3) ◽  
pp. 380-381 ◽  
Author(s):  
Yasuko Kato ◽  
Satoshi Kurisu ◽  
Naoya Mitsuba ◽  
Ken Ishibashi ◽  
Yoshihiro Dohi ◽  
...  
Keyword(s):  
Left Ventricular Hypertrophy ◽  
Primary Aldosteronism ◽  
Qt Interval ◽  
Ventricular Hypertrophy ◽  
Left Ventricular

Regression of left ventricular hypertrophy in primary aldosteronism after adrenalectomy

2020 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Cesare Cuspidi ◽  
Marijana Tadic ◽  
Carla Sala ◽  
Fosca Quarti-Trevano ◽  
Elisa Gherbesi ◽  
...  
Keyword(s):  
Left Ventricular Hypertrophy ◽  
Primary Aldosteronism ◽  
Ventricular Hypertrophy ◽  
Left Ventricular
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