scholarly journals Multisystemic Infarctions in COVID-19: Focus on the Spleen

2020 ◽  
Author(s):  
Mariana Santos Leite Pessoa ◽  
Carla Franco Costa Lima ◽  
Ana Carla Farias Pimentel ◽  
José Carlos Godeiro Costa Júnior ◽  
Jorge Luis Bezerra Holanda
Keyword(s):  
Early Diagnosis ◽  
Splenic Infarction ◽  
Thrombotic Disease ◽  
Coronavirus Infection

The literature suggests that COVID-19 provokes arterial and venous thrombotic events, although the mechanism is still unknown. In this study, we describe patients with confirmed coronavirus infection associated with multisystemic infarction, focusing on splenic infarction. More data are required to elucidate how COVID-19 and thrombotic disease interact and so that preventive and early diagnosis strategies can be developed.

scholarly journals Early diagnosis of SARS Coronavirus infection by real time RT-PCR

2003 ◽  
Vol 28 (3) ◽  
pp. 233-238 ◽  
Author(s):  
Leo L.M. Poon ◽  
Kwok Hung Chan ◽  
On Kei Wong ◽  
Wing Cheong Yam ◽  
Kwok Yung Yuen ◽  
...  
Keyword(s):  
Early Diagnosis ◽  
Real Time ◽  
Sars Coronavirus ◽  
Rt Pcr ◽  
Coronavirus Infection

CHANGE IN THE LEVEL OF IGG ANTIBODIES TO THE SARS-COV-2 (COVID-19) CORONAVIRUS IN THE POPULATION OF THE REGIONS OF THE RUSSIAN FEDERATION AND IN DYNAMICS IN CONVALESCENTS

2020 ◽  
Author(s):  
Ershov A.V. ◽  
Manasova Z.Sh. ◽  
Surova V.D.
Keyword(s):  
Early Diagnosis ◽  
Russian Federation ◽  
Laboratory Tests ◽  
Dynamic Monitoring ◽  
Control Group ◽  
Igg Antibodies ◽  
Coronavirus Infection ◽  
The Russian Federation ◽  
Immunological Changes ◽  
The Moment

The article presents the results of research in the field of early diagnosis and dynamic monitoring of immunological changes in the human body in the course of COVID-19 coronavirus infection and after the disease. The article presents the results of laboratory tests for the presence of IgG antibodies to the SARS-CoV-2 coronavirus in 2112 patients living in 5 regions of the Russian Federation. The aim of this study was to evaluate the dynamics of IgG class antibodies to SARS-CoV-2 coronavirus (COVID-19) in the blood of patients who had a new coronavirus infection. We found that there were no significant changes in the level of IgG antibodies to the SARS-CoV-2 coronavirus from the 14th day of illness to the 3rd month of observation from the moment of the first symptoms of the disease. Starting from the 4th month of observation, the level of antibodies decreased in both groups by multiples in relation to the maximum values, decreasing by the 6th month of observation to the values of the control group. The results of the study can be used to develop an optimal diagnostic, therapeutic and preventive algorithm for reducing infection in the population and the number of severe cases of the disease.

Red Flags: Barriers to Listening and Spoken Language in Children with Hearing Loss

2014 ◽  
Vol 24 (1) ◽  
pp. 11-18
Author(s):  
Andrea Bell ◽  
K. Todd Houston
Keyword(s):  
Hearing Loss ◽  
Early Diagnosis ◽  
Skill Acquisition ◽  
Dynamic Process ◽  
Spoken Language ◽  
Red Flags ◽  
Careful Monitoring ◽  
Auditory Development ◽  
Children With Hearing Loss ◽  
Family Centered

To ensure optimal auditory development for the acquisition of spoken language, children with hearing loss require early diagnosis, effective ongoing audiological management, well fit and maintained hearing technology, and appropriate family-centered early intervention. When these elements are in place, children with hearing loss can achieve developmental and communicative outcomes that are comparable to their hearing peers. However, for these outcomes to occur, clinicians—early interventionists, speech-language pathologists, and pediatric audiologists—must participate in a dynamic process that requires careful monitoring of countless variables that could impact the child's skill acquisition. This paper addresses some of these variables or “red flags,” which often are indicators of both minor and major issues that clinicians may encounter when delivering services to young children with hearing loss and their families.

Neonatal Serum Electrolyte and Proteinuria Screening on 46,XY Ambiguous Genitalia Patients May Allow Early Diagnosis of Denys-Drash Syndrome: A Case Report

Urology ◽  
2020 ◽  
Author(s):  
Angelena Edwards ◽  
Niccolo M. Passoni ◽  
Rebecca Collins ◽  
Smitha Vidi ◽  
Jyothsna Gattineni ◽  
...  
Keyword(s):  
Case Report ◽  
Early Diagnosis ◽  
Ambiguous Genitalia ◽  
Serum Electrolyte ◽  
Drash Syndrome

Serum Vitamin B12 Concentrations among Mothers and Newborns and Follow-up Study to Assess Implication on the Growth Velocity and the Urinary Methylmalonic Acid Excretion

2009 ◽  
Vol 79 (56) ◽  
pp. 297-307 ◽  
Author(s):  
Laila Hussein ◽  
Sahar Abdel Aziz ◽  
Salwa Tapouzada ◽  
Boehles
Keyword(s):  
Early Diagnosis ◽  
Growth Velocity ◽  
Methylmalonic Acid ◽  
Post Partum ◽  
Serum Vitamin ◽  
Vitamin B ◽  
Postnatal Life ◽  
Negative Consequences ◽  
Metabolic Marker ◽  
Biochemical Measurement

Objective:Cobalamin (B12) deficiency has been reported in infants born to mothers with low cobalamin intake. Early diagnosis of vitamin B12 deficiency in infants is critical for the prevention of neurobehavioral disorders. We investigated the relationship between serum vitamin B12 level in newborns and in their healthy mothers who consumed an omnivorous diet. Anthropometry was studied longitudinally to assess the growth velocity of the infants. Urinary methylmalonic acid (MMA) excretion of 6-month old infants was compared retrospectively as the biomarker correlated with the initial serum vitamin B12 concentrations. Methods: Serum cobalamin and blood hemoglobin were determined in 84 pairs of newborns and their mothers. Urinary MMA excretion was measured in the same subjects during the first 6 months of the post partum period. Results: At birth, median serum cobalamin levels were 152.0 pmol/L in the mothers and 296.6 pmol/L in the newborns. Maternal and neonatal serum cobalamin levels had no effect on growth velocity during the first six months of postnatal life. Serum maternal and neonatal cobalamin levels were inversely associated with urinary MMA excretion. Conclusion: Early diagnosis of vitamin B12 status in neonates and infants is crucial, particularly in nutritionally deprived areas. Biochemical measurement of plasma cobalamin or its metabolic marker MMA is highly recommended. Urinary MMA measurement in cobalamin diagnostics provides an advantage in that blood sampling is not required. A vitamin B12 taskforce should be created to alleviate vitamin deficiency and its negative consequences.

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