scholarly journals Atypical Presentation of Glioblastoma Multiforme

2018 ◽  
Author(s):  
Wissam Al-Janabi ◽  
Renee Krabs ◽  
Ximena Arcila-Londono ◽  
Iram Zaman ◽  
Bashiruddin K Hamad
Keyword(s):  
Case Report ◽  
Glioblastoma Multiforme ◽  
Intracranial Pressure ◽  
Brain Mri ◽  
Stage Iv ◽  
Signs And Symptoms ◽  
Careful Analysis ◽  
World Health ◽  
Atypical Presentation ◽  
Initial Symptoms

Background: Glioblastoma multiforme (GBM) is a highly malignant glial tumour classified by the World Health Organization (WHO) as a stage IV astrocytoma. It varies in shape and size and can be cystic, vascular and necrotic. It often appears as a ring-enhancing lesion on magnetic resonance imaging (MRI). The most common symptoms of GBM, such as headache, vomiting and seizures, are due to increased intracranial pressure. The objective of this case report is to describe an atypical presentation of GBM. Case Report: A 53-year-old woman of Italian origin presented with a 2-week history of lack of coordination in her hands and some difficulty in speech. Electromyography for assessment of her arms and cranial bulbar function was normal. However, 2 days later, the patient presented to the emergency department with progressive weakness in her left arm and leg as well as difficulty in speech. Mild left facial asymmetry was noted. A brain MRI revealed a right frontal mass. Stereotactic surgical resection was performed 2 days later, and biopsy confirmed the diagnosis of GBM. Although headache and other features of raised intracranial pressure are the most common initial symptoms of GBM, any atypical neurological or psychiatric presentation in an adult patient should raise suspicion for this tumour. Conclusion: Careful analysis of an adult with atypical signs and symptoms along with thorough review of radiological tests will facilitate early diagnosis of dangerous tumours such as GBM.

scholarly journals Phytophotodermatitis: A Case Report

2020 ◽  
Vol 11 (4) ◽  
pp. 5886-5888
Author(s):  
Asish Kumar Saha ◽  
Asem Veeves Singh ◽  
Anand Vijaya kumar ◽  
Shekhar Sanjayrao Deshpande
Keyword(s):  
Case Report ◽  
Inflammatory Reaction ◽  
Fruit Juice ◽  
Signs And Symptoms ◽  
Skin Inflammation ◽  
Burning Sensation ◽  
Initial Symptoms ◽  
Plant Chemicals ◽  
Affected Person ◽  
Initial Sign

A rare phototoxic dermatological reaction seen in Indian Sub-continent, known as Phytophotodermatitis, occurs with exposure to ultraviolet light after contact with certain plant chemicals. Phytophotodermatitis named from the terms ‘phyto’ means plant, ‘photo’ means light, and ‘dermatitis’ means skin inflammation. The signs and symptoms of Phytophotodermatitis typically initiated 24 hours after comes in contact with skin, and the peak is reached between 48 to 72 hours. The indications may be from mild or severe. The signs are redness, tenderness, burning sensation, pain, inflammation, itching, blistering, thickened layer of skin after blisters rupture. The area of blisters is usually asymmetrical in shape. These are seen in the areas of the skin, that were exposed to the chemical. For example, the drip form of blister seen in the skin if it is exposed to fruit juice. If the skin were brushed against a plant, it would show streaks like pattern. Though the early symptoms subside, within 7-14 days, signs of blackening of the skin may show hyperpigmentation. This stage of Phytophotodermatitis is known as post-inflammatory pigmentation and might last for many months. In some cases, the affected person will have a very mild inflammatory reaction, if they are exposed to sunlight, while some may not even know that they experienced a reaction. The hyperpigmentation is the initial sign to know that they have got Phytophotodermatitis. Initial symptoms get aggravated because of wet skin, sweat and heat. Darkening of skin-colour is observed in the persons while they are exposed to sunlight. In this case, we are reporting about a patient having this condition and the cause for the occurrence.

scholarly journals Atypical Presentation of Traumatic Neuroma: A case report

2017 ◽  
Vol 13 (3) ◽  
pp. 366-369
Author(s):  
Bela Agrawal ◽  
Ajit Kumar Yadav ◽  
Khushboo Goel ◽  
Sajeev Shrestha ◽  
Ashish Shrestha
Keyword(s):  
Case Report ◽  
Smooth Surface ◽  
Histopathological Examination ◽  
Neural Tissue ◽  
Signs And Symptoms ◽  
Mental Foramen ◽  
Atypical Presentation ◽  
Traumatic Neuroma ◽  
Reactive Proliferation

Congenital Traumatic neuroma is a rare disorder that represents a reactive proliferation of neural tissue followingdamage to an adjacent nerve. Rarely these lesions appear in the oral cavity with certain predilection for the mental foramen and the tongue area. However, its presentation on lip is more unusual with only few cases being reported in the literature. Typically diagnosed in middle-aged women, patient complains of pain as a frequent symptom. Clinically, the lip lesions appear as a normal or grayish white nodule with a smooth surface that typically resembles a mucocele. We report here a case of a 37-year old female who presented with similar signs and symptoms and was diagnosed clinically as a mucocele. However, histopathological examination revealed it as a traumatic neuroma that was surgically excised. The patient is under follow-up with no signs of recurrence for 18 months. 

scholarly journals COVID-19-Associated Acute Disseminated Encephalomyelitis – A Case Report

2020 ◽  
Author(s):  
Tianshu Zhang ◽  
Michael B. Rodricks ◽  
Ellen Hirsh
Keyword(s):  
Case Report ◽  
Young Patient ◽  
Clinical Features ◽  
Brain Mri ◽  
Acute Disseminated Encephalomyelitis ◽  
Atypical Presentation ◽  
The Novel ◽  
Head Ct ◽  
Novel Coronavirus ◽  
Mri Changes

AbstractWe present the first described case of acute disseminated encephalomyelitis (ADEM) in a COVID-19 patient. The clinical features with head CT and brain MRI changes were described. Our described case is an atypical presentation of the novel coronavirus in a young patient and is illustrative of the possible approaches to explore the treatable differential etiologies.

scholarly journals Case report: Pediatric patients with COVID-19 presented as multi-system inflammatory syndrome

2020 ◽  
Author(s):  
Amir Saeed ◽  
anahita sanaei ◽  
shabnam Hajiani Ghotbabadi ◽  
Eslam shorafa
Keyword(s):  
Case Report ◽  
Kawasaki Disease ◽  
World Health Organization ◽  
Pediatric Patients ◽  
World Health ◽  
Atypical Presentation ◽  
Case Presentation ◽  
Myocardial Involvement ◽  
Health Organization ◽  
Inflammatory Syndrome

Abstract Background COVID-19 in pediatric patients is typically associated with minimal manifestations and is less severe than adult patients. Recently, there are reports of children with COVID 19 and myocardial involvement from Europe and America that first were assumed to be Kawasaki disease or its atypical presentation. However world health organization has set a new designation for this state; “multi-system involvement syndrome” in children with COVID-19; (MIS-C). Case presentation: Here we report two COVID-19 pediatric patients (two girls aged 10 and 13 years old) with MIS-C. Conclusion Presence of Kawasaki like signs in COVID 19 patients should be an alarming point to consider multi-system inflammatory syndrome; a syndrome with extensive organ involvement and yet indistinct exact pathophysiology.

Atypical Presentation and Progression of Glioblastoma Multiforme in a 6-Year-Old Girl: Multidisciplinary Case Report

2003 ◽  
Vol 25 (3) ◽  
pp. 243-247 ◽  
Author(s):  
Christopher D. Jahraus ◽  
Megan K. Dishop ◽  
Sherry L. Bayliff ◽  
Charles Lee ◽  
William H. St. Clair
Keyword(s):  
Case Report ◽  
Glioblastoma Multiforme ◽  
Atypical Presentation

scholarly journals Burkitt lymphoma of the breast associated with hiv infection – a case report and literature review

Mastology ◽  
2020 ◽  
Vol 30 (Suppl 1) ◽  
Author(s):  
Talita Aparecida Riegas Mendes ◽  
Idam de Oliveira
Keyword(s):  
Case Report ◽  
Literature Review ◽  
Hiv Infection ◽  
Burkitt Lymphoma ◽  
Stage Iv ◽  
Left Breast ◽  
Lymph Node Biopsy ◽  
World Health ◽  
Lactation Period ◽  
Breast Lymphoma

Introduction: Breast lymphoma is a rare variety of this class of tumor in extra-nodal sites, accounting for less than 0.5% of malignant breast neoplasms and less than 3% of extra-nodal lymphomas. The most prevalent type of breast lymphoma is non-Hodgkin lymphoma (NHL) of large B cells. Burkitt lymphoma (BL) occurs in less than 6% of cases and is considered an even rarer subtype of the disease. According to the World Health Organization (WHO), BL can be classified into three clinical forms: endemic (associated with the Epstein-Baar virus), sporadic, and immunodeficiency-related. The clinical presentation of breast lymphoma is similar to that of carcinoma, and imaging tests cannot differentiate them. Objective: This case report aims at providing better knowledge about BL of the breast and conducting a literature review. Case report: A 52-year-old woman with a history of left breast carcinoma (2009) was surgically treated with quadrantectomy, sentinel lymph node biopsy in the left axilla, and adjuvant radiotherapy and hormone therapy. In 2019, she was diagnosed with Human Immunodeficiency Virus (HIV) infection and started antiretroviral therapy (ART). Four months later, she noted nodules in her left breast and underwent imaging and histopathological investigation of the lesions. Immunohistochemical results revealed NHL, with characteristics suggestive of BL of the breast. Positron emission tomography-computed tomography (PET-CT) for disease staging indicated lymphoma in stage IV-A (Ann Arbor Classification, 1988). The patient was admitted by the hematology team of the Hospital de Câncer de Barretos to start chemotherapy. Discussion: BL of the breast affects mainly young women, and its association with the pregnancy/lactation period is not unusual, which suggests a hormonal influence on its development. Secondary breast disease is more common, and differentiating primary and secondary lymphoma can be difficult. When associated with immunodeficiency, it is more frequent in patients infected by HIV, and less in individuals with other immunodeficiency causes. The breast lesion can be characterized by a painless nodule and possible systemic symptoms (sweating, fever, or weight loss). The main management of these cases consists of polychemotherapy, and the benefit of radiotherapy is unclear. Surgical treatments, such as mastectomy, are not indicated and are associated with worse survival. Conclusion: BL of the breast associated with immunodeficiency, concomitant with HIV infection, is an uncommon neoplasm that can progress to a poor prognosis. The appropriate and prompt diagnosis allows starting the best form of treatment and avoids unnecessary surgical procedures.

Severe persistent placoid maculopathy: Atypical presentation in a young male

2020 ◽  
pp. 112067212097782
Author(s):  
Maria Luisa Gois da Fonsêca ◽  
Vivian Afonso ◽  
Arnaldo Furman Bordon ◽  
Raul Nunes Galvarro Vianna
Keyword(s):  
Visual Acuity ◽  
Case Report ◽  
Anterior Segment ◽  
Young Male ◽  
Young Age ◽  
Unusual Presentation ◽  
Atypical Presentation ◽  
Rare Entity ◽  
Initial Symptoms ◽  
Age Range

Introduction: Persistent placoid maculopathy (PPM) is a rare entity that preferably affects males in the age range between 50 and 60 years, but cases at a young age have already been reported. In the latter, the initial symptoms are usually unilateral, without severely decreased visual acuity and anterior segment inflammation. Case report: We report a case of PPM with anterior segment inflammation in a young male. Discussion: Considering the rarity of this illness, the report of an unusual presentation in a young male can aid in the recognition of future cases of PPM.

scholarly journals Abducens Nerve Paralysis Caused due to Increased Intracranial Pressure: A Case Report and Review of Literatures

2017 ◽  
Vol 6 (1) ◽  
pp. 66-69
Author(s):  
Khadijeh Haji Naghi Tehrani ◽  
Zahra Morshedian
Keyword(s):  
Case Report ◽  
Intracranial Pressure ◽  
Nerve Palsy ◽  
Complete Blood Count ◽  
Abducens Nerve ◽  
Signs And Symptoms ◽  
Pseudotumor Cerebri ◽  
Sudden Increase ◽  
Double Vision ◽  
Nerve Paralysis

Background: Double vision due to abducens nerve palsy in patients with Pseudotumor cerebri is a very rare finding and usually occurs by increasing in intracranial pressure (ICP) and therefore by the effect of pressure on abducens nerve. Case Report: A 21-year-old woman has referred to our clinic with symptoms of the headaches, double vision along with nausea and vomiting lasting for three months, with no history of the disease, drug consumption, and the only clinical findings was weighing about 20 Kg for a recent year. In examination VI nerve palsy of the left eye, papilledema of both eyes was reported. The computed tomography (CT) and magnetic resonance imaging (MRI) as a diagnostic test for a patient’s brain lesions shown normal report. Also, other hormone testing and complete blood count were normal. For the next step patient underwent for lumbar puncture (LP), the patient’s cerebrospinal fluid (CSF) pressure was measured more than 120 CmH2O. According to the findings of the examination, patient diagnosed with pseudotumor cerebri and underwent for frequent LP, which during that the headaches and double vision symptoms of patient decreased, which indicates that all signs and symptoms of patients caused by pseudotumor cerebri were due to sudden increase in body weight over the past year. Patient prescribed for Acetazolamide and recommended to lose weight with proper diet. For three months of follow-up, symptoms of increased ICP and papilledema have been cleared. Conclusion: The pseudotumor cerebri is manageable by proper diet, and there is no need for bariatric surgery. [GMJ.2017;6(1):66-69]

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