Air pollution and associated serial lung function and respiratory symptoms among a panel of schoolchildren

2016 ◽  
Vol 2016 (1) ◽  
Author(s):  
Rajen N. Naidoo* ◽  
Shumani Phaswana
Thorax ◽  
2008 ◽  
Vol 64 (7) ◽  
pp. 573-580 ◽  
Author(s):  
M Rosenlund ◽  
F Forastiere ◽  
D Porta ◽  
M De Sario ◽  
C Badaloni ◽  
...  

1990 ◽  
Vol 6 (5) ◽  
pp. 189-197 ◽  
Author(s):  
Gerard Hoek ◽  
Bert Brunekreef ◽  
Peter Hofschreuder ◽  
Mieke Lumens

In January 1985, a decline of primary school children's pulmonary function was observed during an air pollution episode. Ambient 24 hour average levels of SO2, TSP and RSP were in the range of 200–250 μg/m3. The response persisted for at least two weeks. In January 1987, again a decline of school children's pulmonary function was observed associated with an air pollution episode. Levels of TSP were about as elevated as in the 1985 episode. Two weeks after the episode, lung function levels were even lower than during the episode. In June 1987 a long term study was started to investigate potential effects of winter and summer air pollution episodes on pulmonary function and occurrence of acute respiratory symptoms of primary school children. An important issue for this study is the characterization of short term variation of lung function in absence of air pollution. Exposure is characterized by ambient levels of several gases (SO2, NO2, O3, HNP3), PM10, TSP and components of particulate matter (SO2−4, NO-3, H+, NH+4). Sampling is being conducted on a daily basis to obtain a continuous exposure estimate. In the winter of 1987/1988, no air pollution episodes were observed. The study will continue through the winters of 1988/1989, and 1989/1990.


Epidemiology ◽  
2007 ◽  
Vol 18 (Suppl) ◽  
pp. S65
Author(s):  
M Rosenlund ◽  
F Forastiere ◽  
D Porta ◽  
M De Sario ◽  
C Perucci

2019 ◽  
Vol 26 (5) ◽  
Author(s):  
M J Ruzmyn Vilcassim ◽  
George D Thurston ◽  
Lung-Chi Chen ◽  
Chris C Lim ◽  
Eric Saunders ◽  
...  

Abstract Background With the number of annual global travellers reaching 1.2 billion, many individuals encounter greater levels of air pollution when they travel abroad to megacities around the world. This study’s objective was to determine if visits to cities abroad with greater levels of air pollution adversely impact cardiopulmonary health. Methods A total of 34 non-smoking healthy adult participants who travelled abroad to selected cities from the New York City (NYC) metropolitan area were pre-trained to measure lung function, blood pressure and heart rate (HR)/HR variability (HRV) and record symptoms before, during and after travelling abroad. Outdoor particulate matter (PM)2.5 concentrations were obtained from central monitors in each city. Associations between PM exposure concentrations and cardiopulmonary health endpoints were analysed using a mixed effects statistical design. Results East and South Asian cities had significantly higher PM2.5 concentrations compared with pre-travel NYC PM2.5 levels, with maximum concentrations reaching 503 μg/m3. PM exposure–related associations for lung function were statistically significant and strongest between evening Forced Expiratory Volume in the first second (FEV1) and same-day morning PM2.5 concentrations; a 10-μg/m3 increase in outdoor PM2.5 was associated with a mean decrease of 7 mL. Travel to a highly polluted city (PM2.5 > 100 μg/m3) was associated with a 209-ml reduction in evening FEV1 compared with a low polluted city (PM2.5 < 35 μg/m3). In general, participants who travelled to East and South Asian cities experienced increased respiratory symptoms/scores and changes in HR and HRV. Conclusions Exposure to increased levels of PM2.5 in cities abroad caused small but statistically significant acute changes in cardiopulmonary function and respiratory symptoms in healthy young adults. These data suggest that travel-related exposure to increased PM2.5 adversely impacts cardiopulmonary health, which may be particularly important for travellers with pre-existing respiratory or cardiac disease.


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