Disability weights for chronic metallic mercury vapor intoxication to improve estimates of the burden of disease resulting from mercury use in gold mining

2016 ◽  
Vol 2016 (1) ◽  
Author(s):  
Nadine Steckling* ◽  
Dietrich Plass ◽  
Julia Winkelnkemper ◽  
Florian Fischer ◽  
Brecht Devleesschauwer ◽  
...  
Keyword(s):  
Burden Of Disease ◽  
Gold Mining ◽  
Mercury Vapor ◽  
Metallic Mercury ◽  
Disability Weights

Neonatal Mercury Vapor Exposure in an Infant Incubator

PEDIATRICS ◽  
1980 ◽  
Vol 66 (6) ◽  
pp. 988-990
Author(s):  
John F. McLaughlin ◽  
Robert W. Telzrow ◽  
Celia Mae Scott
Keyword(s):  
Newborn Infant ◽  
Body Burden ◽  
Mercury Vapor ◽  
Metallic Mercury ◽  
Heating Unit ◽  
Substantial Body ◽  
Healthy Newborn ◽  
Infant Incubator ◽  
Infant Incubators

A healthy newborn infant acquired a substantial body burden of mercury by inhaling mercury vapor originating from a broken mercury expansion switch in the heating unit of an infant incubator. Highly toxic mercury vapor is produced in quantity by heating otherwise harmless metallic mercury. Switches and thermometers that contain mercury should be removed from infant incubators.

scholarly journals Developing and evaluating national severity distributions for use in Burden of Disease studies: a case study of cancers in Scotland

2019 ◽  
Vol 4 (3) ◽  
Author(s):  
Grant Wyper ◽  
Ian Grant ◽  
Eilidh Fletcher ◽  
Gerry McCartney ◽  
Diane Stockton
Keyword(s):  
Burden Of Disease ◽  
Weighted Average ◽  
Systematic Bias ◽  
Specific Data ◽  
Tract Cancer ◽  
Disability Weights ◽  
Cancer Types ◽  
Relative Differences ◽  
The Impact

BackgroundIncreasingly Burden of Disease (BOD) measures are being used to influence policy decisions because they summarise health loss in an equitable manner. An important part of producing non-fatal BOD estimates are severity distributions (SDs). The Global Burden of Disease (GBD) study use the same SDs across countries due to a lack of available data. Aim To develop and assess the impact of national SDs compared with GBD worldwide severity distributions for 21 cancer types. MethodsPatient-level records from the Scottish Cancer Registry for 21 cancers were obtained and linked to death registrations. We estimated prevalent cancer cases for 2016 and assigned each case to one of four phases (diagnosis and treatment; controlled; metastatic; and terminal) using GBD 2016 study definitions. SDs were calculated by considering relative proportions. The impact of choice of SDs was evaluated by comparing relative differences between weighted-average disability weights (DW) derived using GBD 2016 worldwide SDs with those derived from Scottish SDs. ResultsFor the majority of cancers the most prevalent phase was the controlled phase, which contributed a higher proportion than the combined proportion from the other three phases across all cancers except mesothelioma. Differences in the composition of severity meant that most point-estimates of Scottish severity proportions were out-with the 95% uncertainty intervals. These differences resulted in overestimates of weighted-average DWs based on GBD 2016 worldwide SDs (17 out of 21 cancer types). The largest relative overestimates were for gallbladder and biliary tract cancer, oesophageal cancer and pancreatic cancer (71%, 32% and 31% higher respectively). ConclusionThese findings illustrate a systematic bias introduced by using worldwide SDs. Current non-fatal BOD estimates should not be interpreted too precisely when comparing populations when they rely on data inputs from other countries. It is essential to ensure that any estimates are based upon country-specific data as far as possible.

scholarly journals Disease profile and health-related quality of life (HRQoL) using the EuroQol (EQ-5D + C) questionnaire for chronic metallic mercury vapor intoxication

2015 ◽  
Vol 13 (1) ◽  
Author(s):  
Nadine Steckling ◽  
Dietrich Plass ◽  
Stephan Bose-O’Reilly ◽  
Alfred Bogomir Kobal ◽  
Alexander Krämer ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Mercury Vapor ◽  
Health Related Quality ◽  
Metallic Mercury ◽  
Related Quality ◽  
Health Related

Human health risk assessment of mercury vapor around artisanal small-scale gold mining area, Palu city, Central Sulawesi, Indonesia

2016 ◽  
Vol 124 ◽  
pp. 155-162 ◽  
Author(s):  
Koyomi Nakazawa ◽  
Osamu Nagafuchi ◽  
Tomonori Kawakami ◽  
Takanobu Inoue ◽  
Kuriko Yokota ◽  
...  
Keyword(s):  
Risk Assessment ◽  
Health Risk ◽  
Human Health ◽  
Health Risk Assessment ◽  
Gold Mining ◽  
Human Health Risk ◽  
Mercury Vapor ◽  
Mining Area ◽  
Small Scale ◽  
Central Sulawesi

scholarly journals Disability weights from a household survey in a low socio-economic setting: how does it compare to the global burden of disease 2010 study?

2016 ◽  
Vol 9 (1) ◽  
pp. 31754 ◽  
Author(s):  
Ian Neethling ◽  
Jennifer Jelsma ◽  
Lebogang Ramma ◽  
Helen Schneider ◽  
Debbie Bradshaw
Keyword(s):  
Burden Of Disease ◽  
Household Survey ◽  
Global Burden Of Disease ◽  
Global Burden ◽  
Disability Weights

scholarly journals Global Burden of Disease of Mercury Used in Artisanal Small-Scale Gold Mining

2017 ◽  
Vol 83 (2) ◽  
pp. 234 ◽  
Author(s):  
Nadine Steckling ◽  
Myriam Tobollik ◽  
Dietrich Plass ◽  
Claudia Hornberg ◽  
Bret Ericson ◽  
...  
Keyword(s):  
Burden Of Disease ◽  
Gold Mining ◽  
Global Burden Of Disease ◽  
Small Scale ◽  
Global Burden

scholarly journals Revised estimates of leprosy disability weights for assessing the global burden of disease: A systematic review and individual patient data meta-analysis

2021 ◽  
Vol 15 (3) ◽  
pp. e0009209
Author(s):  
Shri Lak Nanjan Chandran ◽  
Anuj Tiwari ◽  
Anselmo Alves Lustosa ◽  
Betul Demir ◽  
Bob Bowers ◽  
...  
Keyword(s):  
Burden Of Disease ◽  
Disease Burden ◽  
Individual Patient Data ◽  
Meta Analysis ◽  
Disability Weight ◽  
Global Burden Of Disease ◽  
Global Burden ◽  
Individual Level ◽  
Disability Weights ◽  
Level Data

Background Leprosy is a chronic bacterial infection caused by Mycobacterium leprae, which may lead to physical disability, stigma, and discrimination. The chronicity of the disease and disabilities are the prime contributors to the disease burden of leprosy. The current figures of the disease burden in the 2017 global burden of disease study, however, are considered to be under-estimated. In this study, we aimed to systematically review the literature and perform individual patient data meta-analysis to estimate new disability weights for leprosy, using Health-Related Quality of Life (HRQOL) data. Methodology/principal findings The search strategy included all major databases with no restriction on language, setting, study design, or year of publication. Studies on human populations that have been affected by leprosy and recorded the HRQOL with the Short form tool, were included. A consortium was formed with authors who could share the anonymous individual-level data of their study. Mean disability weight estimates, sorted by the grade of leprosy disability as defined by WHO, were estimated for individual participant data and pooled using multivariate random-effects meta-analysis. Eight out of 14 studies from the review were included in the meta-analysis due to the availability of individual-level data (667 individuals). The overall estimated disability weight for grade 2 disability was 0.26 (95%CI: 0.18–0.34). For grade 1 disability the estimated weight was 0.19 (95%CI: 0.13–0.26) and for grade 0 disability it was 0.13 (95%CI: 0.06–0.19). The revised disability weight for grade 2 leprosy disability is four times higher than the published GBD 2017 weights for leprosy and the grade 1 disability weight is nearly twenty times higher. Conclusions/significance The global burden of leprosy is grossly underestimated. Revision of the current disability weights and inclusion of disability caused in individuals with grade 0 leprosy disability will contribute towards a more precise estimation of the global burden of leprosy.

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