CORDBLOOD ACRYLAMIDE AND GLYCIDAMIDE HAEMOGLOBIN ADDUCTS, METABOLIC POLYMORPHISMS AND MICRONUCLEUS FREQUENCY

2011 ◽  
Vol 2011 (1) ◽  
Author(s):  
Vincenzo Fontana ◽  
Micheline Kirsch-Volders ◽  
Kim Vande Loock ◽  
Hans von Stedingk ◽  
Margareta Törnqvist ◽  
...  
Keyword(s):  
Haemoglobin Adducts ◽  
Micronucleus Frequency

Micronucleus frequency in erythrocytes of mice after long-term exposure to radiofrequency radiation

2007 ◽  
Vol 83 (4) ◽  
pp. 213-220 ◽  
Author(s):  
Jukka Juutilainen ◽  
Päivi Heikkinen ◽  
Harri Soikkeli ◽  
Jorma Mäki-Paakkanen
Keyword(s):  
Radiofrequency Radiation ◽  
Micronucleus Frequency

Assessment of long-term health risks after accidental exposure using haemoglobin adducts of epichlorohydrin

2014 ◽  
Vol 231 (3) ◽  
pp. 378-386 ◽  
Author(s):  
Klaus-Michael Wollin ◽  
Michael Bader ◽  
Michael Müller ◽  
Werner Lilienblum ◽  
Michael Csicsaky
Keyword(s):  
Health Risks ◽  
Accidental Exposure ◽  
Haemoglobin Adducts

Comparative evaluation of genotoxic effect in subjects with chronic periodontitis with and without type 2 diabetes mellitus

2019 ◽  
Vol 11 (1) ◽  
pp. 29-36
Author(s):  
Dr.Smruti Lulla ◽  
Dr.Amita Mali ◽  
Dr. AashwiinMiglani ◽  
Dr. VidyaDodwad ◽  
Dr. SachinMangalekar ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Dna Damage ◽  
Type 2 Diabetes Mellitus ◽  
Chronic Periodontitis ◽  
Periodontal Diseases ◽  
Genotoxic Effect ◽  
Micronucleus Frequency ◽  
Group A

Aims: The aim of the study was to compare the genotoxic effect by assessing the micronucleus frequency (MNF), as a biomarker for DNA damage, in subjects with chronic periodontitis with and without type 2 Diabetes Mellitus. Methods and Material: For the study, a total of 65 subjects were take and divided into three groups. Group A included 30 subjects with Generalised Chronic Periodontitis, Group Bincluded 30 Subjects with Chronic Periodontitis with type 2 diabetes mellitus and Group C included 5 systemically and periodontally healthy subjects. Periodontal clinical examination was carried out. A slide was prepared using the blood sample collected from the subjects which was fixed in 5% geimsa solution and was observed under the microscope. Later the scoring of micronuclei was done. Statistical analysis used: Descriptive and inferential statistical analyses were carried out in the present study. Analysis of Variance (ANOVA) was used to find the significance of study parameters and test the equality of three or more means of more than two groups. Tukey’s post hoc analysis was used to compare parameters of each and every group. Results: The mean score of the micronuclei observed in group A, B and C were 10.23, 14.87 and 1 respectively i.e. group B showed significantly greater damage than other two groups. Conclusions: It was concluded that the score of micronucleus frequency may be considered as an important biomarker of genotoxic damage that is DNA damage in subjects with chronic localised as well as systemic diseases like type 2 diabetes, as well as Periodontal diseases.

Increased micronucleus frequency in lymphocytes from smokers with lung cancer

1996 ◽  
Vol 349 (1) ◽  
pp. 43-50 ◽  
Author(s):  
Tsun-Jen Cheng ◽  
David C. Christiani ◽  
Xiping Xu ◽  
John C. Wain ◽  
John K. Wiencke ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Micronucleus Frequency

DNA repair gene XRCC1 and XPD polymorphisms and their association with coronary artery disease risks and micronucleus frequency

2007 ◽  
Vol 22 (6) ◽  
pp. 355-360 ◽  
Author(s):  
Mehmet Guven ◽  
Gulgun S. Guven ◽  
Erdinc Oz ◽  
Ahmet Ozaydin ◽  
Bahadir Batar ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Dna Repair ◽  
Coronary Artery ◽  
Repair Gene ◽  
Micronucleus Frequency ◽  
Dna Repair Gene ◽  
Disease Risks ◽  
Artery Disease

scholarly journals Increased micronucleus frequency in exfoliated cells of the buccal mucosa in hairdressers

2010 ◽  
Vol 9 (3) ◽  
pp. 1921-1928 ◽  
Author(s):  
L.N. Rickes ◽  
M.C. Alvarengo ◽  
T.M. Souza ◽  
G.L. Garcias ◽  
M.G. Martino-Roth
Keyword(s):  
Buccal Mucosa ◽  
Micronucleus Frequency ◽  
Exfoliated Cells
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