LONG TERM EXPOSURE TO ORGANOCHLORINE PESTICIDES AND THYROID HORMONE LEVELS IN CHILDREN FROM CIDADE DOS MENINOS, RJ, BRAZIL

2011 ◽  
Vol 2011 (1) ◽  
Author(s):  
Carmen Freire ◽  
Rosalina Koifman ◽  
Paula Sarcinelli ◽  
Ana Cristina Rosa ◽  
Ruth Clapauch ◽  
...  
Author(s):  
J H Parr

Serum concentration of free T3 and, in female patients, FT4, were found to be lower in 20 asymptomatic, moderately-poor or well controlled, diabetics treated with insulin than in a group of non-diabetic subjects. Over a mean 3-month period of the study a significant fall occurred in HbA1 concentration in both groups of diabetics without change in free thyroid hormone levels. The mean capillary blood glucose, fasting free insulin and fasting lipid concentrations, other than high density lipoprotein (HDL) cholesterol, did not change. No correlations were found between the changes in HbA1 and free thyroid hormone concentrations. Improvement in long term metabolic control did not influence free thyroid hormone levels in well controlled and moderately-poor controlled diabetics, taking insulin.


2020 ◽  
Vol 33 (1) ◽  
pp. 21-33 ◽  
Author(s):  
Mahshid Gheidarloo ◽  
Roya Kelishadi ◽  
Silva Hovsepian ◽  
Mojtaba Keikha ◽  
Mahin Hashemipour

AbstractIn this systematic review, the association between prenatal exposure to organochlorine pesticides (OCPs) and neonatal thyroid hormone levels was studied. A systematic search of scientific literature was performed from the PubMed, SCOPUS and ISI web of science electronic bibliographic databases. The search strategy for the review was [(organochlorine OR “organochlorine pesticides” OR “organochlorine pollutants” OR “organochlorine pollutant”) AND (“thyroid hormone” OR triiodothyronine OR Thyroxine OR “fetal thyroid function” OR “thyroid function” OR “Thyroid Stimulating Hormone” AND “prenatal” AND “maternal exposure”)] in English sources. In this review, 305 papers (PubMed: 30; Scopus: 29; ISI: 246) were identified through an electronic database search. Twenty-seven articles were assessed for eligibility, from which 16 qualified articles were selected for the final evaluation. The most common OCP metabolites which were evaluated in order were hexachlorobenzene (HCB) (13 studies), pp-dichlorodiphenyldichloroethylene (pp-DDE) (13 studies), hexachlorocyclohexane (HCH) (10 studies) and dichlorodiphenyltrichlorethane (DDT) (eight studies). A review of the documents related to the association of prenatal exposure of OCPs with fetal or neonatal thyroid function tests provides us with heterogeneous data in this field. Factors such as differences in the studied populations and their area, ethnic and genetic background, time and rate of exposure, possible interaction of other thyroid-disrupting environmental factors and dietary intake of micronutrients such as iodine and/or selenium are considered the main limitations for making an accurate conclusion. For some OCPs including DDT, DDE, HCH and HCB, there are supporting evidences, and it is suggested that their exposure could potentially alter the fetal thyroid function and consequently impair the neurodevelopment process of the infants.


1995 ◽  
Vol 27 (07) ◽  
pp. 318-321 ◽  
Author(s):  
M. Cokelare ◽  
P. Daenens ◽  
M. Van Boven ◽  
E. Kühn ◽  
E. Decuypere ◽  
...  

1985 ◽  
Vol 78 (3) ◽  
pp. 443-450 ◽  
Author(s):  
Gregory D. Borowski ◽  
Catherine D. Garofano ◽  
Leslie I. Rose ◽  
Scott R. Spielman ◽  
Heschi R. Rotmensch ◽  
...  

2013 ◽  
Vol 79 (1) ◽  
pp. 71-78 ◽  
Author(s):  
Cecilia Follin ◽  
Katarina Link ◽  
Thomas Wiebe ◽  
Christian Moëll ◽  
Jonas Björk ◽  
...  

2014 ◽  
Vol 129 ◽  
pp. 47-51 ◽  
Author(s):  
Chengcheng Li ◽  
Yibin Cheng ◽  
Quan Tang ◽  
Shaobin Lin ◽  
Yonghong Li ◽  
...  

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