AIR POLLUTION EXPOSURE DURING PREGNANCY AND MATERNAL AND FETAL C-REACTIVE PROTEIN LEVELS. THE GENERATION R STUDY

2011 ◽  
Vol 2011 (1) ◽  
Author(s):  
Edith H van den Hooven ◽  
Vincent WV Jaddoe ◽  
Albert Hofman ◽  
Vincent WV Jaddoe ◽  
Edith H van den Hooven ◽  
...  
Keyword(s):  
Air Pollution ◽  
C Reactive Protein ◽  
Protein Levels ◽  
Reactive Protein ◽  
Air Pollution Exposure ◽  
Exposure During Pregnancy ◽  
Pollution Exposure

scholarly journals Chronic Air Pollution Exposure during Pregnancy and Maternal and Fetal C-Reactive Protein Levels: The Generation R Study

2012 ◽  
Vol 120 (5) ◽  
pp. 746-751 ◽  
Author(s):  
Edith H. van den Hooven ◽  
Yvonne de Kluizenaar ◽  
Frank H. Pierik ◽  
Albert Hofman ◽  
Sjoerd W. van Ratingen ◽  
...  
Keyword(s):  
Air Pollution ◽  
C Reactive Protein ◽  
Protein Levels ◽  
Reactive Protein ◽  
Air Pollution Exposure ◽  
Exposure During Pregnancy ◽  
Pollution Exposure

PARTICULATE AIR POLLUTION EXPOSURE AND C-REACTIVE PROTEIN DURING EARLY PREGNANCY

2011 ◽  
Vol 2011 (1) ◽  
Author(s):  
Pei-Chen Lee ◽  
Evelyn O. Talbott ◽  
James M. Roberts ◽  
Janet M. Catov ◽  
Ravi K. Sharma ◽  
...  
Keyword(s):  
Air Pollution ◽  
Early Pregnancy ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Particulate Air Pollution ◽  
Air Pollution Exposure ◽  
Pollution Exposure

scholarly journals Particulate Air Pollution Exposure and C-reactive Protein During Early Pregnancy

Epidemiology ◽  
2011 ◽  
Vol 22 (4) ◽  
pp. 524-531 ◽  
Author(s):  
Pei-Chen Lee ◽  
Evelyn O. Talbott ◽  
James M. Roberts ◽  
Janet M. Catov ◽  
Ravi K. Sharma ◽  
...  
Keyword(s):  
Air Pollution ◽  
Early Pregnancy ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Particulate Air Pollution ◽  
Air Pollution Exposure ◽  
Pollution Exposure

scholarly journals Ambient air pollution exposure during pregnancy and cardio-metabolic markers in cord blood: The Healthy Start study

2021 ◽  
Vol 2021 (1) ◽  
Author(s):  
Chloe Friedman ◽  
Dana Dabelea ◽  
Lizan D. Bloemsma ◽  
Deborah SK Thomas ◽  
Jennifer L. Peel ◽  
...  
Keyword(s):  
Air Pollution ◽  
Cord Blood ◽  
Ambient Air ◽  
Healthy Start ◽  
Ambient Air Pollution ◽  
Metabolic Markers ◽  
Air Pollution Exposure ◽  
Exposure During Pregnancy ◽  
Pollution Exposure

scholarly journals Air pollution-induced placental alterations: an interplay of oxidative stress, epigenetics, and the aging phenotype?

2019 ◽  
Vol 11 (1) ◽  
Author(s):  
N. D. Saenen ◽  
D. S. Martens ◽  
K. Y. Neven ◽  
R. Alfano ◽  
H. Bové ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Air Pollution ◽  
Energy Metabolism ◽  
Early Life ◽  
Nitrosative Stress ◽  
Later Life ◽  
Modes Of Action ◽  
Air Pollution Exposure ◽  
Exposure During Pregnancy ◽  
Pollution Exposure

Abstract According to the “Developmental Origins of Health and Disease” (DOHaD) concept, the early-life environment is a critical period for fetal programming. Given the epidemiological evidence that air pollution exposure during pregnancy adversely affects newborn outcomes such as birth weight and preterm birth, there is a need to pay attention to underlying modes of action to better understand not only these air pollution-induced early health effects but also its later-life consequences. In this review, we give an overview of air pollution-induced placental molecular alterations observed in the ENVIRONAGE birth cohort and evaluate the existing evidence. In general, we showed that prenatal exposure to air pollution is associated with nitrosative stress and epigenetic alterations in the placenta. Adversely affected CpG targets were involved in cellular processes including DNA repair, circadian rhythm, and energy metabolism. For miRNA expression, specific air pollution exposure windows were associated with altered miR-20a, miR-21, miR-146a, and miR-222 expression. Early-life aging markers including telomere length and mitochondrial DNA content are associated with air pollution exposure during pregnancy. Previously, we proposed the air pollution-induced telomere-mitochondrial aging hypothesis with a direct link between telomeres and mitochondria. Here, we extend this view with a potential co-interaction of different biological mechanisms on the level of placental oxidative stress, epigenetics, aging, and energy metabolism. Investigating the placenta is an opportunity for future research as it may help to understand the fundamental biology underpinning the DOHaD concept through the interactions between the underlying modes of action, prenatal environment, and disease risk in later life. To prevent lasting consequences from early-life exposures of air pollution, policy makers should get a basic understanding of biomolecular consequences and transgenerational risks.

A hybrid model using temporal and spatial regression to estimate air pollution exposure during pregnancy

2013 ◽  
Vol 2013 (1) ◽  
pp. 5038
Author(s):  
Elena Proietti ◽  
Edgar Delgado-Eckert ◽  
Georgette Stern ◽  
Danielle Vienneau ◽  
Ming-Yi Tsai ◽  
...  
Keyword(s):  
Air Pollution ◽  
Hybrid Model ◽  
Spatial Regression ◽  
Air Pollution Exposure ◽  
Exposure During Pregnancy ◽  
Temporal And Spatial ◽  
Pollution Exposure

Air Pollution Exposure During Pregnancy And Fetal Markers Of Metabolic Function: The Mirec Study

2015 ◽  
Vol 2015 (1) ◽  
pp. 3397
Author(s):  
Eric Lavigne ◽  
Jillian Ashley-Martin ◽  
Linda Dodds ◽  
Tye E. Arbuckle ◽  
Perry Hystad ◽  
...  
Keyword(s):  
Air Pollution ◽  
Metabolic Function ◽  
Air Pollution Exposure ◽  
Exposure During Pregnancy ◽  
Pollution Exposure
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