scholarly journals PCB-Related Alteration of Thyroid Hormones and Thyroid Hormone ReceptorGene Expression in Free-Ranging Harbor Seals (Phoca vitulina)

2006 ◽  
Vol 114 (7) ◽  
pp. 1024-1031 ◽  
Author(s):  
Maki Tabuchi ◽  
Nik Veldhoen ◽  
Neil Dangerfield ◽  
Steven Jeffries ◽  
Caren C. Helbing ◽  
...  
2004 ◽  
Vol 103 (3-4) ◽  
pp. 131-141 ◽  
Author(s):  
Tracey Goldstein ◽  
Jonna A.K. Mazet ◽  
Frances M.D. Gulland ◽  
Teri Rowles ◽  
James T. Harvey ◽  
...  

1998 ◽  
Vol 76 (1) ◽  
pp. 48-55 ◽  
Author(s):  
Martin Haulena ◽  
David J Aubin ◽  
Padraig J Duignan

The postnatal period in phocid seals is metabolically demanding, requiring mobilization of maternal energy stores, which are then transferred via the milk for subsequent deposition in the pup. Thyroid hormones may be important modulators of these processes, and so we monitored circulating levels of free and total thyroxine (T4), triiodothyronine (T3), and reverse T3 (rT3) in 13 free-ranging female harbour seals (Phoca vitulina) and their pups for up to 25 days post partum. Early total and free T4 levels, percentage of free T4, total and free T3 levels, rT3 levels, and rT3:T3 ratios were significantly higher in pups than in mothers. Total and free T4 levels, percentage of free T4, free T3 and rT3, levels, and rT3:T3 ratios in pups decreased significantly over the lactation period, while maternal total and free T4 levels increased significantly. Our findings highlight the dynamic nature of thyroid hormones and their involvement in regulating metabolism throughout this important period. This is the first report examining free T3 and rT3 levels in phocid seals.


2008 ◽  
Vol 34 (2) ◽  
pp. 149-156 ◽  
Author(s):  
Ilka Hasselmeier ◽  
Sonja Fonfara ◽  
Jörg Driver ◽  
Ursula Siebert

2019 ◽  
Vol 45 (3) ◽  
pp. 349-355
Author(s):  
Ronald A. Kastelein ◽  
Robin Gransier ◽  
Marloe Brouwers ◽  
Lean Helder-Hoek

2020 ◽  
Vol 46 (2) ◽  
pp. 119-123
Author(s):  
Anders Galatius ◽  
Jonas Teilmann ◽  
Jakob Tougaard ◽  
Rune Dietz

2021 ◽  
Vol 53 (04) ◽  
pp. 272-279
Author(s):  
Chaochao Ma ◽  
Xiaoqi Li ◽  
Lixin Liu ◽  
Xinqi Cheng ◽  
Fang Xue ◽  
...  

AbstractThyroid hormone reference intervals are crucial for diagnosing and monitoring thyroid dysfunction during early pregnancy, and the dynamic change trend of thyroid hormones during pregnancy can assist clinicians to assess the thyroid function of pregnant women. This study aims to establish early pregnancy related thyroid hormones models and reference intervals for pregnant women. We established two derived databases: derived database* and derived database#. Reference individuals in database* were used to establish gestational age-specific reference intervals for thyroid hormones and early pregnancy related thyroid hormones models for pregnant women. Individuals in database# were apparently healthy non-pregnant women. The thyroid hormones levels of individuals in database# were compared with that of individuals in database* using nonparametric methods and the comparative confidence interval method. The differences in thyroid stimulating hormone and free thyroxine between early pregnant and non-pregnant women were statistically significant (p<0.0001). The reference intervals of thyroid stimulating hormone, free thyroxine and free triiodothyronine for early pregnant women were 0.052–3.393 μIU/ml, 1.01–1.54 ng/dl, and 2.51–3.66 pg/ml, respectively. Results concerning thyroid stimulating hormone and free thyroxine reference intervals of early pregnancy are comparable with those from other studies using the same detection platform. Early pregnancy related thyroid hormones models showed various change patterns with gestational age for thyroid hormones. Early pregnancy related thyroid hormones models and reference intervals for pregnant women were established, so as to provide accurate and reliable reference basis for the diagnosing and monitoring of maternal thyroid disfunction in early pregnancy.


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